U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CAMK2D calcium/calmodulin dependent protein kinase II delta [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100101557, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    CAMK2D
    Gene description
    calcium/calmodulin dependent protein kinase II delta
    See related
    Ensembl:ENSOCUG00000023650
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 15
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 15 NC_067388.1 (32596237..32911172)

    Chromosome 15 - NC_067388.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2 Neighboring gene arylsulfatase family member J Neighboring gene uncharacterized LOC127483156 Neighboring gene uncharacterized LOC127483155 Neighboring gene uncharacterized LOC127483157 Neighboring gene ankyrin 2 Neighboring gene ribosomal protein S20 pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_067388.1 Chromosome 15 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes. Simon M, et al. J Mol Cell Cardiol, 2021 Dec. PMID 34371035, Free PMC Article
    2. Effects of calmodulin-dependent protein kinase II inhibitor, KN-93, on electrophysiological features of rabbit hypertrophic cardiac myocytes. Ke J, et al. J Huazhong Univ Sci Technolog Med Sci, 2012 Aug. PMID 22886958
    3. New alternatively spliced variants of calmodulin-dependent protein kinase II from rabbit liver. Takeuchi M, et al. Gene, 1998 Oct 9. PMID 9852955

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CaMKIIdelta post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes.
      Title: CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes.
    2. A specific inhibitor of CaMKII can effectively inhibit the occurrence of EADs.
      Title: Effects of calmodulin-dependent protein kinase II inhibitor, KN-93, on electrophysiological features of rabbit hypertrophic cardiac myocytes.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    calcium/calmodulin-dependent protein kinase type II subunit delta
    Names
    CaM kinase II subunit delta
    CaMK-II subunit delta
    calmodulin-dependent protein kinase II-delta dash
    NP_001093424.1
    XP_051675245.1
    XP_051675246.1
    XP_051675247.1
    XP_051675248.1
    XP_051675249.1
    XP_051675250.1
    XP_051675251.1
    XP_051675252.1
    XP_051675253.1
    XP_051675255.1
    XP_051675256.1
    XP_051675257.1
    XP_051675258.1
    XP_051675259.1
    XP_051675260.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099954.1 → NP_001093424.1  calcium/calmodulin-dependent protein kinase type II subunit delta

      See identical proteins and their annotated locations for NP_001093424.1

      Status: PROVISIONAL

      Source sequence(s)
      D14906
      UniProtKB/TrEMBL
      G1TVE5
      Related
      ENSOCUP00000021029.3, ENSOCUT00000029366.3
      Conserved Domains (3) summary
      smart00220
      Location:14 → 272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:346 → 473
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067388.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      32596237..32911172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051819285.1 → XP_051675245.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1

    2. XM_051819292.1 → XP_051675252.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X8

    3. XM_051819289.1 → XP_051675249.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X5

      UniProtKB/Swiss-Prot
      O77708

    4. XM_051819293.1 → XP_051675253.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X9

    5. XM_051819287.1 → XP_051675247.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3

    6. XM_051819291.1 → XP_051675251.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X7

    7. XM_051819296.1 → XP_051675256.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X11

    8. XM_051819300.1 → XP_051675260.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X15

    9. XM_051819286.1 → XP_051675246.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2

    10. XM_051819290.1 → XP_051675250.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6

    11. XM_051819295.1 → XP_051675255.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X10

    12. XM_051819299.1 → XP_051675259.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X14

    13. XM_051819288.1 → XP_051675248.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4

    14. XM_051819297.1 → XP_051675257.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X12

    15. XM_051819298.1 → XP_051675258.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X13

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O77708.2 GenPept UniProtKB/Swiss-Prot:O77708

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.