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    SETX senataxin [ Equus caballus (horse) ]

    Gene ID: 100066679, updated on 8-Mar-2024

    Summary

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    Official Symbol
    SETXprovided by VGNC
    Official Full Name
    senataxinprovided by VGNC
    Primary source
    VGNC:VGNC:22881
    See related
    Ensembl:ENSECAG00000012019
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See SETX in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 25 NC_009168.3 (35311028..35390363, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 25 NC_009168.2 (34677122..34754755, complement)

    Chromosome 25 - NC_009168.3Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 27 Neighboring gene U2 spliceosomal RNA Neighboring gene netrin G2 Neighboring gene uncharacterized LOC106782578 Neighboring gene transcription termination factor 1 Neighboring gene cilia and flagella associated protein 77

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription termination site sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in termination of RNA polymerase II transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable helicase senataxin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009168.3 Reference EquCab3.0 Primary Assembly

      Range
      35311028..35390363 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023629201.1 → XP_023484969.1  probable helicase senataxin isoform X2

      UniProtKB/TrEMBL
      A0A3Q2GZN2, F6QHG0
      Related
      ENSECAP00000026543.2, ENSECAT00000038847.3
      Conserved Domains (3) summary
      pfam12726
      Location:37 → 334
      SEN1_N; SEN1 N terminal
      pfam13086
      Location:1959 → 2244
      AAA_11; AAA domain
      pfam13087
      Location:2251 → 2450
      AAA_12; AAA domain

    2. XM_023629204.1 → XP_023484972.1  probable helicase senataxin isoform X3

      UniProtKB/TrEMBL
      A0A3Q2GXH9
      Conserved Domains (3) summary
      pfam12726
      Location:75 → 372
      SEN1_N; SEN1 N terminal
      pfam13086
      Location:1997 → 2282
      AAA_11; AAA domain
      cl22977
      Location:2289 → 2433
      UvrD_C_2; UvrD-like helicase C-terminal domain

    3. XM_023629203.1 → XP_023484971.1  probable helicase senataxin isoform X2

      UniProtKB/TrEMBL
      A0A3Q2GZN2, F6QHG0
      Conserved Domains (3) summary
      pfam12726
      Location:37 → 334
      SEN1_N; SEN1 N terminal
      pfam13086
      Location:1959 → 2244
      AAA_11; AAA domain
      pfam13087
      Location:2251 → 2450
      AAA_12; AAA domain

    4. XM_023629200.1 → XP_023484968.1  probable helicase senataxin isoform X1

      UniProtKB/TrEMBL
      F6QHG0
      Related
      ENSECAP00000085978.1, ENSECAT00000088565.1
      Conserved Domains (3) summary
      pfam12726
      Location:37 → 334
      SEN1_N; SEN1 N terminal
      pfam13086
      Location:1941 → 2226
      AAA_11; AAA domain
      pfam13087
      Location:2233 → 2432
      AAA_12; AAA domain
    Nucleotide Protein
    Heading Accession and Version

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