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    MARCHF8 membrane associated ring-CH-type finger 8 [ Equus caballus (horse) ]

    Gene ID: 100062110, updated on 8-Mar-2024

    Summary

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    Official Symbol
    MARCHF8provided by VGNC
    Official Full Name
    membrane associated ring-CH-type finger 8provided by VGNC
    Primary source
    VGNC:VGNC:51572
    See related
    Ensembl:ENSECAG00000002745
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    MARCH8
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (81300009..81413449, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 1 NC_009144.2 (80444232..80556874, complement)

    Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 13 subfamily A member 1 Neighboring gene arachidonate 5-lipoxygenase Neighboring gene uncharacterized LOC102147419 Neighboring gene zinc finger AN1-type containing 4 Neighboring gene WASH complex subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables MHC protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of peptide antigen via MHC class II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in early endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MARCH8
    Names
    membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009144.3 Reference EquCab3.0 Primary Assembly

      Range
      81300009..81413449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023647915.1 → XP_023503683.1  E3 ubiquitin-protein ligase MARCH8 isoform X2

      Conserved Domains (1) summary
      cd16698
      Location:380 → 431
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    2. XM_023647864.1 → XP_023503632.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    3. XM_023647929.1 → XP_023503697.1  E3 ubiquitin-protein ligase MARCH8 isoform X4

      UniProtKB/TrEMBL
      A0A3Q2GXC1
      Related
      ENSECAP00000025164.3, ENSECAT00000046276.3
      Conserved Domains (1) summary
      cd16698
      Location:342 → 393
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    4. XM_023647922.1 → XP_023503690.1  E3 ubiquitin-protein ligase MARCH8 isoform X3

      Conserved Domains (1) summary
      cd16698
      Location:359 → 410
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    5. XM_023647940.1 → XP_023503708.1  E3 ubiquitin-protein ligase MARCH8 isoform X6

      UniProtKB/TrEMBL
      A0A3Q2KTU8
      Related
      ENSECAP00000002075.2, ENSECAT00000002899.3
      Conserved Domains (1) summary
      cd16698
      Location:77 → 128
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    6. XM_023647896.1 → XP_023503664.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    7. XM_023647876.1 → XP_023503644.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    8. XM_023647880.1 → XP_023503648.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    9. XM_023647902.1 → XP_023503670.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    10. XM_023647908.1 → XP_023503676.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    11. XM_023647886.1 → XP_023503654.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    12. XM_023647867.1 → XP_023503635.1  E3 ubiquitin-protein ligase MARCH8 isoform X1

      Conserved Domains (1) summary
      cd16698
      Location:397 → 448
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    13. XM_023647936.1 → XP_023503704.1  E3 ubiquitin-protein ligase MARCH8 isoform X5

      Conserved Domains (1) summary
      cd16698
      Location:314 → 365
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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