U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ITGB1 integrin subunit beta 1 [ Equus caballus (horse) ]

    Gene ID: 100055024, updated on 8-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ITGB1provided by VGNC
    Official Full Name
    integrin subunit beta 1provided by VGNC
    Primary source
    VGNC:VGNC:19175
    See related
    Ensembl:ENSECAG00000022498
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    CD29
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 29
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 29 NC_009172.3 (6049658..6095732)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 29 NC_009172.2 (5036908..5077786)

    Chromosome 29 - NC_009172.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102149425 Neighboring gene uncharacterized LOC102149498 Neighboring gene coiled-coil domain containing 7 Neighboring gene enhancer of polycomb homolog 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables C-X3-C chemokine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables collagen binding involved in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fibronectin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables laminin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    integrin beta-1
    Names
    integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301217.1 → NP_001288146.1  integrin beta-1 precursor

      Status: INFERRED

      Source sequence(s)
      DN508960, JL640389, PJAA01000030
      UniProtKB/TrEMBL
      A0A3Q2IDL5, A0A9L0SCX1
      Related
      ENSECAP00000046507.1, ENSECAT00000034042.3
      Conserved Domains (3) summary
      pfam00362
      Location:41 → 471
      Integrin_beta; Integrin, beta chain
      pfam07965
      Location:647 → 734
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:764 → 803
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009172.3 Reference EquCab3.0 Primary Assembly

      Range
      6049658..6095732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023631884.1 → XP_023487652.1  integrin beta-1 isoform X1

      UniProtKB/TrEMBL
      A0A9L0SKP9
      Conserved Domains (4) summary
      smart00187
      Location:34 → 464
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07974
      Location:602 → 630
      EGF_2; EGF-like domain
      pfam07965
      Location:640 → 727
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:757 → 796
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    2. XM_003364340.4 → XP_003364388.3  integrin beta-1 isoform X1

      UniProtKB/TrEMBL
      A0A9L0SKP9
      Conserved Domains (4) summary
      smart00187
      Location:34 → 464
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07974
      Location:602 → 630
      EGF_2; EGF-like domain
      pfam07965
      Location:640 → 727
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:757 → 796
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    3. XM_005606848.3 → XP_005606905.2  integrin beta-1 isoform X2

      UniProtKB/TrEMBL
      A0A9L0SKP9
      Related
      ENSECAP00000086162.1, ENSECAT00000079787.1
      Conserved Domains (4) summary
      smart00187
      Location:34 → 464
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07974
      Location:602 → 630
      EGF_2; EGF-like domain
      pfam07965
      Location:640 → 727
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:757 → 795
      Integrin_b_cyt; Integrin beta cytoplasmic domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.