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    MTF1 metal regulatory transcription factor 1 [ Equus caballus (horse) ]

    Gene ID: 100054605, updated on 8-Mar-2024

    Summary

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    Official Symbol
    MTF1provided by VGNC
    Official Full Name
    metal regulatory transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:20408
    See related
    Ensembl:ENSECAG00000017235
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 2 NC_009145.3 (19881396..19921463)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 2 NC_009145.2 (19833698..19873458)

    Chromosome 2 - NC_009145.3Genomic Context describing neighboring genes Neighboring gene splicing factor 3a subunit 3 Neighboring gene inositol polyphosphate-5-phosphatase B Neighboring gene chromosome 2 C1orf122 homolog Neighboring gene yrdC N6-threonylcarbamoyltransferase domain containing Neighboring gene mannosidase endo-alpha like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metal regulatory transcription factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009145.3 Reference EquCab3.0 Primary Assembly

      Range
      19881396..19921463
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023633176.1 → XP_023488944.1  metal regulatory transcription factor 1 isoform X1

      UniProtKB/TrEMBL
      F6PL56
      Related
      ENSECAP00000015036.2, ENSECAT00000018428.4
      Conserved Domains (4) summary
      COG5048
      Location:93 → 291
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:285 → 328
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:236 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26464
      Location:405 → 542
      Atrophin-1; Atrophin-1 family

    2. XM_023633180.1 → XP_023488948.1  metal regulatory transcription factor 1 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:93 → 291
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:285 → 328
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:236 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26464
      Location:405 → 542
      Atrophin-1; Atrophin-1 family

    3. XM_014737342.2 → XP_014592828.1  metal regulatory transcription factor 1 isoform X3

      Conserved Domains (4) summary
      COG5048
      Location:5 → 203
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:148 → 165
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:157 → 183
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:143 → 231
      zf-C2H2_8; C2H2-type zinc ribbon
    Nucleotide Protein
    Heading Accession and Version

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