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    HIC2 HIC ZBTB transcriptional repressor 2 [ Equus caballus (horse) ]

    Gene ID: 100051007, updated on 8-Mar-2024

    Summary

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    Official Symbol
    HIC2provided by VGNC
    Official Full Name
    HIC ZBTB transcriptional repressor 2provided by VGNC
    Primary source
    VGNC:VGNC:18780
    See related
    Ensembl:ENSECAG00000017997
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See HIC2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 8 NC_009151.3 (5247051..5276146, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 8 NC_009151.2 (3246101..3254621, complement)

    Chromosome 8 - NC_009151.3Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serpin family D member 1 Neighboring gene transmembrane protein 191C Neighboring gene RIMS-binding protein 3A Neighboring gene ubiquitin conjugating enzyme E2 L3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hypermethylated in cancer 2 protein
    Names
    hypermethylated in cancer 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009151.3 Reference EquCab3.0 Primary Assembly

      Range
      5247051..5276146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023646788.1 → XP_023502556.1  hypermethylated in cancer 2 protein isoform X2

      Conserved Domains (4) summary
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:447 → 469
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:40 → 140
      BTB; BTB/POZ domain
      pfam13465
      Location:489 → 514
      zf-H2C2_2; Zinc-finger double domain

    2. XM_023646787.1 → XP_023502555.1  hypermethylated in cancer 2 protein isoform X1

      UniProtKB/TrEMBL
      F6PW69
      Related
      ENSECAP00000015515.2, ENSECAT00000018982.3
      Conserved Domains (4) summary
      sd00017
      Location:536 → 556
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:534 → 556
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:40 → 140
      BTB; BTB/POZ domain
      pfam13465
      Location:576 → 601
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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