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    IREB2 iron responsive element binding protein 2 [ Equus caballus (horse) ]

    Gene ID: 100050493, updated on 8-Mar-2024

    Summary

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    Official Symbol
    IREB2provided by VGNC
    Official Full Name
    iron responsive element binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:19129
    See related
    Ensembl:ENSECAG00000016731
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (117181973..117239297)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 1 NC_009144.2 (116044039..116101296)

    Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene SKI8 subunit of superkiller complex Neighboring gene uncharacterized LOC111775655 Neighboring gene cellular retinoic acid binding protein 1 Neighboring gene hydroxylysine kinase Neighboring gene proteasome 20S subunit alpha 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aconitate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron-responsive element binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in citrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    iron-responsive element-binding protein 2
    Names
    Iron-responsive element-binding protein 2-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009144.3 Reference EquCab3.0 Primary Assembly

      Range
      117181973..117239297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001488966.5 → XP_001489016.1  iron-responsive element-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2KSD3
      Related
      ENSECAP00000014872.3, ENSECAT00000018244.3
      Conserved Domains (3) summary
      cd01586
      Location:85 → 642
      AcnA_IRP; Aconitase A catalytic domain
      cd01580
      Location:746 → 913
      AcnA_IRP_Swivel; Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group ...
      PTZ00092
      Location:3 → 962
      PTZ00092; aconitate hydratase-like protein; Provisional

    2. XM_023652652.1 → XP_023508420.1  iron-responsive element-binding protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A9L0RUB3
      Conserved Domains (1) summary
      cl28376
      Location:2 → 866
      AcnA; Aconitase A [Energy production and conversion]

    3. XM_023652643.1 → XP_023508411.1  iron-responsive element-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A9L0RUB3, A0A9L0SPP7
      Related
      ENSECAP00000075973.1, ENSECAT00000109137.1
      Conserved Domains (1) summary
      cl28376
      Location:20 → 943
      AcnA; Aconitase A [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version

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