LOC100049001 tryptase [Canis lupus familiaris (dog)] - Gene

Summary

Gene symbol: LOC100049001
Gene description: tryptase
See related: Ensembl:ENSCAFG00845022862
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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Genomic context

Location:: chromosome: 6

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	6	NC_051810.1 (39850138..39852120)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	6	NC_006588.4 (40772274..40773700)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	6	NC_049227.1 (39978489..39979916)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	6	NC_049266.1 (39527216..39528642)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	6	NC_049747.1 (39499857..39501283)

Chromosome 6 - NC_051810.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tryptase

NP_001091024.1

EC 3.4.21.59

XP_038523470.1

EC 3.4.21.59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001097555.2 → NP_001091024.1 tryptase precursor

See identical proteins and their annotated locations for NP_001091024.1

Status: VALIDATED

Source sequence(s)

DN431247, M24664

UniProtKB/Swiss-Prot

P15944

UniProtKB/TrEMBL

A0A8C0JM32, A0A8C0PYV7, A0A8I3PGM2

Related

ENSCAFP00845031769.1, ENSCAFT00845040586.1

Conserved Domains (1) summary

cd00190
Location:31 → 269

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051810.1 Reference ROS_Cfam_1.0

Range

39850138..39852120

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038667542.1 → XP_038523470.1 tryptase isoform X1

Conserved Domains (1) summary

smart00020
Location:31 → 222

Tryp_SPc; Trypsin-like serine protease