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    SFTPC surfactant protein C [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009162, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SFTPC
    Gene description
    surfactant protein C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    SFTP2
    Orthologs
    human mouse all
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    Genomic context

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    See SFTPC in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259237.1 (566385..569243)

    NW_026259237.1Genomic Context describing neighboring genes Neighboring gene receptor accessory protein 4 Neighboring gene leucine rich repeat LGI family member 3 Neighboring gene bone morphogenetic protein 1 Neighboring gene phytanoyl-CoA 2-hydroxylase interacting protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_026259237 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Canine hydrophobic surfactant polypeptide SP-C. A lipopeptide with one thioester-linked palmitoyl group. Johansson J, et al. FEBS Lett, 1991 Apr 9. PMID 2015882
    2. cDNA sequence and alternative mRNA splicing of surfactant-associated protein C (SP-C) in rabbit lung. Connelly I, et al. Biochim Biophys Acta, 1992 Jul 29. PMID 1643107
    3. Developmental regulation of surfactant-associated proteins in rabbit fetal lung in vivo. Durham PL, et al. Exp Lung Res, 1992 Nov-Dec. PMID 1468410
    4. Rabbit surfactant protein C: cDNA cloning and regulation of alternatively spliced surfactant protein C mRNAs. Boggaram V, et al. Am J Physiol, 1992 Dec. PMID 1335697

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in respiratory gaseous exchange by respiratory system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in alveolar lamellar body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pulmonary surfactant-associated protein C
    Names
    SP-C
    pulmonary surfactant-associated proteolipid SPL(Val)
    type I SP-C
    type II SP-C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082322.1 → NP_001075791.1  pulmonary surfactant-associated protein C

      See identical proteins and their annotated locations for NP_001075791.1

      Status: PROVISIONAL

      Source sequence(s)
      S51597
      UniProtKB/Swiss-Prot
      P22398
      Conserved Domains (3) summary
      smart00019
      Location:1 → 189
      SF_P; Pulmonary surfactant proteins
      smart01039
      Location:94 → 189
      BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer
      pfam08999
      Location:1 → 93
      SP_C-Propep; Surfactant protein C, N terminal propeptide

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NW_026259237.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      566385..569243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008249865.3 → XP_008248087.2  pulmonary surfactant-associated protein C isoform X1

      UniProtKB/Swiss-Prot
      P22398
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P22398.3 GenPept UniProtKB/Swiss-Prot:P22398

    Gene LinkOut

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