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    LOC100008771 calcitonin gene-related peptide 2 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100008771, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC100008771
    Gene description
    calcitonin gene-related peptide 2
    See related
    Ensembl:ENSOCUG00000002452
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
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    Genomic context

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    See LOC100008771 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 1 NC_067374.1 (170527499..170532821, complement)

    Chromosome 1 - NC_067374.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 3B Neighboring gene vitamin D 25-hydroxylase Neighboring gene 60S ribosomal protein L32 Neighboring gene calcitonin gene-related peptide 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067374.1 Chromosome 1 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Study on the sense neuropeptides of nasal mucosa in the allergic rhinitis animal model]. Shi S, et al. Lin Chuang Er Bi Yan Hou Ke Za Zhi, 2006 Jun. PMID 16929833
    2. Variation of plasma levels of endothelin, calcitonin gene-related peptide, nitric oxide, and malondialdehyde in acute myocardial ischemia reperfusion injury in a rabbit model. Zhao YB, et al. Genet Mol Res, 2015 May 25. PMID 26125755
    3. H. pylori acutely inhibits gastric secretion by activating CGRP sensory neurons coupled to stimulation of somatostatin and inhibition of histamine secretion. Zaki M, et al. Am J Physiol Gastrointest Liver Physiol, 2013 Apr 15. PMID 23392237

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Dynamic monitoring and comparison of plasma levels of ET, CGRP, NO, and MDA as well as SOD activity revealed that appropriate intervention of these factors may reduce reperfusion injury
      Title: Variation of plasma levels of endothelin, calcitonin gene-related peptide, nitric oxide, and malondialdehyde in acute myocardial ischemia reperfusion injury in a rabbit model.
    2. The reciprocal changes in SST and histamine secretion in gastric Helicobacter infection were due to release of CGRP from sensory neurons.
      Title: H. pylori acutely inhibits gastric secretion by activating CGRP sensory neurons coupled to stimulation of somatostatin and inhibition of histamine secretion.
    3. Substance P and CGRP correlate with the occurrence and development of allergic rhinitis.
      Title: [Study on the sense neuropeptides of nasal mucosa in the allergic rhinitis animal model].
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcitonin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calcitonin gene-related peptide 2; calcitonin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067374.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      170527499..170532821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008266541.3 → XP_008264763.3  calcitonin gene-related peptide 2 isoform X3

    2. XM_002708829.3 → XP_002708875.1  calcitonin gene-related peptide 2 isoform X5

      UniProtKB/TrEMBL
      A0A5F9C784
      Related
      ENSOCUP00000029641.1
      Conserved Domains (2) summary
      smart00113
      Location:80 → 122
      CALCITONIN; calcitonin
      pfam00214
      Location:1 → 123
      Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family

    3. XM_017349435.2 → XP_017204924.2  calcitonin isoform X2

    4. XM_017349434.2 → XP_017204923.2  calcitonin isoform X1

    5. XM_017349438.2 → XP_017204927.1  calcitonin isoform X4

      UniProtKB/TrEMBL
      G1U9R2, Q7M2Z4
      Related
      ENSOCUP00000002117.3

    6. XM_017349445.2 → XP_017204934.1  calcitonin isoform X4

      UniProtKB/TrEMBL
      G1U9R2, Q7M2Z4
    Nucleotide Protein
    Heading Accession and Version

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