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    ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100008624, updated on 3-Apr-2024

    Summary

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    Gene symbol
    ITIH3
    Gene description
    inter-alpha-trypsin inhibitor heavy chain 3
    See related
    Ensembl:ENSOCUG00000011077
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    ITI-HC3
    Orthologs
    human mouse all
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    Genomic context

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    See ITIH3 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 9 NC_067382.1 (96255384..96267645, complement)

    Chromosome 9 - NC_067382.1Genomic Context describing neighboring genes Neighboring gene musculoskeletal, embryonic nuclear protein 1 Neighboring gene inter-alpha-trypsin inhibitor heavy chain 4 Neighboring gene inter-alpha-trypsin inhibitor heavy chain 1 Neighboring gene NIMA related kinase 4 Neighboring gene signal peptidase complex subunit 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067382.1 Chromosome 9 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hyaluronan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inter-alpha-trypsin inhibitor heavy chain H3
    Names
    ITI heavy chain H3
    inter-alpha-inhibitor heavy chain 3
    inter-alpha-trypsin inhibitor heavy chain3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082008.1 → NP_001075477.1  inter-alpha-trypsin inhibitor heavy chain H3 precursor

      See identical proteins and their annotated locations for NP_001075477.1

      Status: PROVISIONAL

      Source sequence(s)
      AB050593
      UniProtKB/Swiss-Prot
      Q9GLY5
      UniProtKB/TrEMBL
      A0A5F9DMU6
      Related
      ENSOCUP00000046804.1, ENSOCUT00000041385.1
      Conserved Domains (4) summary
      smart00609
      Location:29 → 158
      VIT; Vault protein Inter-alpha-Trypsin domain
      cd01461
      Location:281 → 462
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      TIGR03788
      Location:47 → 602
      marine_srt_targ; marine proteobacterial sortase target protein
      pfam06668
      Location:697 → 884
      ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067382.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      96255384..96267645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051851036.1 → XP_051706996.1  inter-alpha-trypsin inhibitor heavy chain H3 isoform X4

    2. XM_051851034.1 → XP_051706994.1  inter-alpha-trypsin inhibitor heavy chain H3 isoform X3

    3. XM_051851033.1 → XP_051706993.1  inter-alpha-trypsin inhibitor heavy chain H3 isoform X2

    4. XM_051851032.1 → XP_051706992.1  inter-alpha-trypsin inhibitor heavy chain H3 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9GLY5.1 GenPept UniProtKB/Swiss-Prot:Q9GLY5

    Gene LinkOut

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