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CAV2 is preferentially expressed in basal-like cancers and is associated with poor prognosis |
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Caveolin-2 was expressed in the sinusoidal endothelial cells and the smooth muscle cells of the unparied arteries of hepatpcellular carcinoma specimens. |
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Observational study of gene-disease association. (HuGE Navigator) |
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Data suggests a possible involvement of serine 36-phosphorylated caveolin-2 in modulating mitosis. |
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Positive staining resulted in shorter survival in patients with esophageal squamous cell carcinoma. |
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Overexpression of caveolin-2 is associated with inflammatory breast cancer |
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caveolin-2 may play a role in lamellar granule assembly, trafficking, and/or function. |
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Heterologously and endogenously expressed D1 dopamine receptors in renal cells are associated with and regulated by caveolin-2. |
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Actin cytoskeleton is involved as part of a caveolar complex in the regulation of myometrial maxi-K channel function. |
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caveolae and caveolins are integral membrane components in basal and ciliated epithelial cellsin rats, mice, and humans, indicating a crucial role in these cell types; in addition to their physiological role, they may be involved in airway infection |
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11. |
increased expression of caveolins in proliferating bile ductules in primary biliary cirrhosis may be related to the homeostasis of cholesterol transport in regenerating bile ductules in liver |
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CAV2 identified and immunolocalized in the caveola-vesicle complexes (CVC )present in erythrocytes infected with P. vivax |
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13. |
The presence of different caveolin isoforms in many cell types of the human retina, is reported. |
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Data show that ER alpha and not ER beta silences caveolin-1/-2 expression in an epigenetic fashion in neuronal cells. |
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New evidence demonstrating that Cav-2 undergoes phosphorylation at both tyrosines 19 and 27 also reveals that tyrosine phosphorylation of Cav-2 has no effect on its targeting to lipid rafts, but clearly disrupts hetero-oligomerization of Cav-2 with Cav-1. |
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16. |
PPARgamma ligands increased the levels of caveolin-2 2-5-fold in a concentration-dependent manner within 24 h. Nonthiazolidinedione PPARgamma ligands elevated caveolin-2 protein 3-4-fold. |
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17. |
In Caco-2 cells, a polarized cell line derived from human colon cancer that does not express caveolin 1 (Cav-1), there was no detectable expression of caveolin 2 (Cav-2). |