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2012 1
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The novel miR-7515 decreases the proliferation and migration of human lung cancer cells by targeting c-Met.
Lee JM, Yoo JK, Yoo H, Jung HY, Lee DR, Jeong HC, Oh SH, Chung HM, Kim JK. Lee JM, et al. Mol Cancer Res. 2013 Jan;11(1):43-53. doi: 10.1158/1541-7786.MCR-12-0355. Epub 2012 Oct 18. Mol Cancer Res. 2013. PMID: 23087254
In this study, we report the identification of a novel miRNA, miR-7515, from lung cancer cells. The novel miR-7515 was characterized using various predictive programs and experimental methods. miR-7515 was able to forming a stem-loop stru …
In this study, we report the identification of a novel miRNA, miR-7515, from lung cancer cells. The novel miR-7515 …
Long noncoding RNA FTX promotes epithelial-mesenchymal transition of epithelial ovarian cancer through modulating miR-7515/TPD52 and activating Met/Akt/mTOR.
Li Y, Zhu X, Zhang C, Yin Y, Chen L, Liu Y, He A, Xia F. Li Y, et al. Histol Histopathol. 2023 Dec;38(12):1487-1498. doi: 10.14670/HH-18-620. Epub 2023 Jan 9. Histol Histopathol. 2023. PMID: 37140169
Western blot was conducted to measure the expressions of E-cadherin, N-cadherin, Met, phosphorylated (p)-Met, Akt, p-Akt, mTOR and p-mTOR. LncBase and TargetScan predicted the binding of miR-7515 with FTX, and the binding of TPD52 with miR-7515, respec …
Western blot was conducted to measure the expressions of E-cadherin, N-cadherin, Met, phosphorylated (p)-Met, Akt, p-Akt, mTOR and p-mTOR. L …
FAM201A knockdown inhibits proliferation and invasion of lung adenocarcinoma cells by regulating miR-7515/GLO1 axis.
Huang J, Yu Q, Zhou Y, Chu Y, Jiang F, Wang Q. Huang J, et al. J Cell Physiol. 2021 Aug;236(8):5620-5632. doi: 10.1002/jcp.30250. Epub 2021 Mar 9. J Cell Physiol. 2021. PMID: 33687075
Moreover, we demonstrated that FAM201A affected LUAD progression via targeting miR-7515 to promote GLO1 expression. FAM201A downregulation also suppressed LUAD development in vivo experiment. ...
Moreover, we demonstrated that FAM201A affected LUAD progression via targeting miR-7515 to promote GLO1 expression. FAM201A do …
miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.
Lei S, Zeng Z, He Z, Cao W. Lei S, et al. Oncol Rep. 2021 Sep;46(3):200. doi: 10.3892/or.2021.8151. Epub 2021 Jul 23. Oncol Rep. 2021. PMID: 34296285 Free PMC article.
The results revealed that the expression levels of miR-7515 were downregulated in PC, which predicted a poor clinical outcome. The overexpression of miR-7515 significantly decreased the proliferation, invasive and migratory abilities of PC cells in vit …
The results revealed that the expression levels of miR-7515 were downregulated in PC, which predicted a poor clinical outcome. …
microRNA-1321 and microRNA-7515 contribute to the progression of non-small cell lung cancer by targeting CDC20.
Hu H, Tou FF, Mao WM, Xu YL, Jin H, Kuang YK, Han CB, Guo CY. Hu H, et al. Kaohsiung J Med Sci. 2022 May;38(5):425-436. doi: 10.1002/kjm2.12500. Epub 2022 Jan 20. Kaohsiung J Med Sci. 2022. PMID: 35050556 Free article.
After CDC20 inhibition, the malignant phenotype of NSCLC cells was reverted. miR-1321 and miR-7515 targeted CDC20 and exhibited the same anti-tumor effects as CDC20 silencing. Functional rescue experiments showed that CDC20 overexpression averted the anti-tumor effe …
After CDC20 inhibition, the malignant phenotype of NSCLC cells was reverted. miR-1321 and miR-7515 targeted CDC20 and exhibite …
MicroRNAs differential expression profile in metastatic colorectal cancer: A pilot study with literature review.
Francone E, Gentilli S, Santori G, Stabilini C, Fornaro R, Frascio M. Francone E, et al. Surg Oncol. 2021 Jun;37:101524. doi: 10.1016/j.suronc.2021.101524. Epub 2021 Jan 31. Surg Oncol. 2021. PMID: 33556883 Review.
Bioinformatic analysis of solid biopsies revealed 16 miRNAs (11 upregulated and 5 downregulated) differently expressed between metastatic and non-metastatic groups, with three miRNAs (miR-7515, miR-7109-5p and miR-6831-5p) never linked to colorectal cancer before. . …
Bioinformatic analysis of solid biopsies revealed 16 miRNAs (11 upregulated and 5 downregulated) differently expressed between metastatic an …
A Study on microRNAs Targeting the Genes Overexpressed in Lung Cancer and their Codon Usage Patterns.
Chakraborty S, Nath D. Chakraborty S, et al. Mol Biotechnol. 2022 Oct;64(10):1095-1119. doi: 10.1007/s12033-022-00491-3. Epub 2022 Apr 18. Mol Biotechnol. 2022. PMID: 35435592
., MUC5B (miR-4479, miR-1227-5p, miR-3940-5p, miR-604, miR-4455, miR-4267, miR-6750-3p, miR-4530, miR-5587-5p, miR-4508, miR-4534, miR-4443, miR-4253, miR-1321, miR-4655-5p, miR-4297, miR-4296, miR-1268a, miR-3178, miR-4750-3p, miR-1306-3p, miR-1268b, miR-3656, miR-1233-3p, miR-6 …
., MUC5B (miR-4479, miR-1227-5p, miR-3940-5p, miR-604, miR-4455, miR-4267, miR-6750-3p, miR-4530, miR-5587-5p, miR-4508, miR-4534, miR-4443, …
The effects of exosomes derived from trabecular meshwork cells on Schlemm's canal endothelial cells.
Takahashi E, Saruwatari J, Fujimoto T, Tanoue Y, Fukuda T, Inoue T. Takahashi E, et al. Sci Rep. 2021 Nov 9;11(1):21942. doi: 10.1038/s41598-021-01450-9. Sci Rep. 2021. PMID: 34754027 Free PMC article.
Isolated exosomes were rich in miRNAs, with downregulated miR-23a-5p and upregulated miR-3942-5p and miR-7515 levels following Col-1 or TGF-beta2 stimulation. Next, a miRNA-mRNA network under TGF-beta2 stimulation was constructed. ...Our data showed that TM cells ma …
Isolated exosomes were rich in miRNAs, with downregulated miR-23a-5p and upregulated miR-3942-5p and miR-7515 levels following …
Differential MicroRNA Expression Profiles in Primary and Recurrent Epithelial Ovarian Cancer.
Chong GO, Jeon HS, Han HS, Son JW, Lee YH, Hong DG, Lee YS, Cho YL. Chong GO, et al. Anticancer Res. 2015 May;35(5):2611-7. Anticancer Res. 2015. PMID: 25964536
Moreover, 4 specific microRNAs were the most significantly down-expressed in recurrent EOC: miR-8084, miR-3201, miR-3613 and miR-7515. CONCLUSION: Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. ...
Moreover, 4 specific microRNAs were the most significantly down-expressed in recurrent EOC: miR-8084, miR-3201, miR-3613 and miR-7 …