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A genetic variant conferred high expression of CAV2 promotes pancreatic cancer progression and associates with poor prognosis.
Zhu Y, Tian J, Peng X, Wang X, Yang N, Ying P, Wang H, Li B, Li Y, Zhang M, Cai Y, Lu Z, Niu S, Li Y, Zhong R, Chang J, Miao X. Zhu Y, et al. Eur J Cancer. 2021 Jul;151:94-105. doi: 10.1016/j.ejca.2021.04.008. Epub 2021 May 8. Eur J Cancer. 2021. PMID: 33975060
RESULTS: We identified the CAV1-CAV2 locus tagged by rs8940 was significantly associated with PDAC prognosis, and rs10249656 in the 3'untranslated region of CAV2 was the real functional variant, which upregulated CAV2 expression through abolishing miR-548s binding. …
RESULTS: We identified the CAV1-CAV2 locus tagged by rs8940 was significantly associated with PDAC prognosis, and rs10249656 in the 3'untran …
A Novel lncRNA Regulates the Toll-Like Receptor Signaling Pathway and Related Immune Function by Stabilizing FOS mRNA as a Competitive Endogenous RNA.
Fan H, Lv Z, Gan L, Ning C, Li Z, Yang M, Zhang B, Song B, Li G, Tang D, Gao J, Yan S, Wang Y, Liu J, Guo Y. Fan H, et al. Front Immunol. 2019 Apr 17;10:838. doi: 10.3389/fimmu.2019.00838. eCollection 2019. Front Immunol. 2019. PMID: 31057556 Free PMC article.
Furthermore, DA treatment also reduced B lymphocyte apoptosis and promoted the differentiation of B lymphocytes into plasma cells, which in turn resulted in the production of more immunoglobulins and the promotion of antigen presentation. In vitro, using HEK293FT cells, we demons …
Furthermore, DA treatment also reduced B lymphocyte apoptosis and promoted the differentiation of B lymphocytes into plasma cells, which in …