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Page 1
The effects of metformin on autophagy.
Lu G, Wu Z, Shang J, Xie Z, Chen C, Zhang C. Lu G, et al. Biomed Pharmacother. 2021 May;137:111286. doi: 10.1016/j.biopha.2021.111286. Epub 2021 Jan 30. Biomed Pharmacother. 2021. PMID: 33524789 Free article. Review.
Secondly, some signaling pathways were involved in the process of metformin inhibiting autophagy, such as AMPK-related signaling pathways (AMPK/NF-kappaB and other undetermined AMPK-related signaling pathways), Hedgehog, miR-570-3p, miR-142-3p, and MiR-3127-5p …
Secondly, some signaling pathways were involved in the process of metformin inhibiting autophagy, such as AMPK-related signaling pathways (A …
Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway.
Sun Y, Chen C, Zhang P, Xie H, Hou L, Hui Z, Xu Y, Du Q, Zhou X, Su B, Gao W. Sun Y, et al. Sci Rep. 2014 Oct 6;4:6527. doi: 10.1038/srep06527. Sci Rep. 2014. PMID: 25284075 Free PMC article.
The oncogene ABL1 was a direct miR-3127-5p target, and miR-3127-5p regulated the activation of the Abl/Ras/ERK pathway and transactivated downstream proliferation/metastasis-associated molecules. Overexpression of miR-3127- …
The oncogene ABL1 was a direct miR-3127-5p target, and miR-3127-5p regulated the activation of the …
LINC00174 Facilitates Proliferation and Migration of Colorectal Cancer Cells via MiR-3127-5p/ E2F7 Axis.
Ma Y, Li Y, Tang Y, Tang N, Wang D, Li X. Ma Y, et al. J Microbiol Biotechnol. 2021 Aug 28;31(8):1098-1108. doi: 10.4014/jmb.2103.03001. J Microbiol Biotechnol. 2021. PMID: 34226413 Free PMC article.
In addition, miR-3127-5p mimic partially reversed the malignant phenotype of CRC cells induced by LINC00174. Besides, E2F7 was a target gene of miR-3127-5p, and LINC00174 repressed miR-3127-5p to regulate E2F7. ...
In addition, miR-3127-5p mimic partially reversed the malignant phenotype of CRC cells induced by LINC00174. Besides, E …
Downregulation of miR-3127-5p promotes epithelial-mesenchymal transition via FZD4 regulation of Wnt/beta-catenin signaling in non-small-cell lung cancer.
Yang Y, Sun Y, Wu Y, Tang D, Ding X, Xu W, Su B, Gao W. Yang Y, et al. Mol Carcinog. 2018 Jul;57(7):842-853. doi: 10.1002/mc.22805. Epub 2018 Apr 14. Mol Carcinog. 2018. PMID: 29566281
We found that metastatic NSCLC tissues showed markedly downregulated miR-3127-5p expression. Transforming growth factor-beta1 (TGF-beta1) treatment induced EMT in A549 and H1299 cells, and downregulation of miR-3127-5p could result in the …
We found that metastatic NSCLC tissues showed markedly downregulated miR-3127-5p expression. Transforming growth factor …
Long non-coding RNAs LINC00689 inhibits the apoptosis of human nucleus pulposus cells via miR-3127-5p/ATG7 axis-mediated autophagy.
Wang C, Chen R, Zhu X, Zhang X. Wang C, et al. Open Med (Wars). 2022 Nov 22;17(1):1821-1832. doi: 10.1515/med-2022-0544. eCollection 2022. Open Med (Wars). 2022. PMID: 36475062 Free PMC article.
Interrelations of LINC00689, miR-3127-5p, and ATG7 were analyzed. LINC00689 was down-regulated yet miR-3127-5p was up-regulated in NPCs. LINC00689 could competitively bind with miR-3127-5p, and ATG7 was targeted by …
Interrelations of LINC00689, miR-3127-5p, and ATG7 were analyzed. LINC00689 was down-regulated yet miR-3127 …
Metformin Affects Paclitaxel Sensitivity of Ovarian Cancer Cells Through Autophagy Mediated by Long Noncoding RNASNHG7/miR-3127-5p Axis.
Yu Z, Wang Y, Wang B, Zhai J. Yu Z, et al. Cancer Biother Radiopharm. 2022 Nov;37(9):792-801. doi: 10.1089/cbr.2019.3390. Epub 2020 Jun 9. Cancer Biother Radiopharm. 2022. PMID: 32522016
RNA immunoprecipitation assay detected the relationship between SNHG7 and miR-3127-5p. Then, the binding correlation between SNHG7 and miR-3127-5p was predicted by starBase and verified by the dual-luciferase reporter. ...Conclusion: The …
RNA immunoprecipitation assay detected the relationship between SNHG7 and miR-3127-5p. Then, the binding correlation be …
CircPAPPA Regulates the Proliferation, Migration, Invasion, Apoptosis, and Cell Cycle of Trophoblast Cells Through the miR-3127-5p/HOXA7 Axis.
Li J, Han J, Zhao A, Zhang G. Li J, et al. Reprod Sci. 2022 Apr;29(4):1215-1225. doi: 10.1007/s43032-021-00802-0. Epub 2022 Jan 3. Reprod Sci. 2022. PMID: 34978042
However, the role of circRNA pregnancy-associated plasma protein A (circPAPPA) in PE is less studied. The expression levels of circPAPPA, miR-3127-5p, and homeobox A7 (HOXA7) were determined by quantitative real-time PCR. ...Moreover, HOXA7 was a target of …
However, the role of circRNA pregnancy-associated plasma protein A (circPAPPA) in PE is less studied. The expression levels of circPAPPA, …
LINC00319 promotes migration, invasion and epithelial-mesenchymal transition process in cervical cancer by regulating miR-3127-5p/RPP25 axis.
Yang J, Hou S, Liang B. Yang J, et al. In Vitro Cell Dev Biol Anim. 2020 Feb;56(2):145-153. doi: 10.1007/s11626-019-00425-5. Epub 2020 Jan 15. In Vitro Cell Dev Biol Anim. 2020. PMID: 31942724
Further, overexpression of LINC00319 accelerates cell migration, invasion and EMT in cervical cancer. Moreover, LINC00319 could bind with miR-3127-5p and negatively regulated its expression. Besides, RPP25 was targeted by miR-3127-5p, and …
Further, overexpression of LINC00319 accelerates cell migration, invasion and EMT in cervical cancer. Moreover, LINC00319 could bind with …
Long non-coding RNA PVT1/microRNA miR-3127-5p/NCK-associated protein 1-like axis participates in the pathogenesis of abdominal aortic aneurysm by regulating vascular smooth muscle cells.
Huang Y, Ren L, Li J, Zou H. Huang Y, et al. Bioengineered. 2021 Dec;12(2):12583-12596. doi: 10.1080/21655979.2021.2010384. Bioengineered. 2021. PMID: 34898354 Free PMC article.
Luciferase reporter assays addressed the possible interaction between miR-3127-5p and PVT1 or NCKAP1L, which was predicted by starBase analysis. ...In conclusion, PVT1 participates in AAA progression through the miR-3127-5p/NCKAP1L axis a …
Luciferase reporter assays addressed the possible interaction between miR-3127-5p and PVT1 or NCKAP1L, which was predic …
21 results