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miR-1245a promotes the proliferation and invasion of colon adenocarcinoma by targeting BRCA2.
Pan Z, Gan W, Liang C, Xiao Y, Zhang Y, Yang W, Hou Z, Chen S, Zeng B, Li Y. Pan Z, et al. Ann Transl Med. 2019 Dec;7(23):777. doi: 10.21037/atm.2019.11.29. Ann Transl Med. 2019. PMID: 32042793 Free PMC article.
RESULTS: miR-1245a is upregulated in CA cells and tissues. Additionally, the high expression of miR-1245a was related to poor survival. ...The rescue experiment further showed that miR-1245a could restore the effect of BRCA2 on CA. CONCLU …
RESULTS: miR-1245a is upregulated in CA cells and tissues. Additionally, the high expression of miR-1245a was re …
Hsa_circ_0006677 regulates special AT-rich binding protein-2-mediated tumor-suppressive effect via functioning as a miR-1245a sponge in non-small cell lung cancer.
Sui X, Liu Z, Niu L, Yin B, Huo C. Sui X, et al. Bioengineered. 2022 Feb;13(2):3760-3774. doi: 10.1080/21655979.2022.2031400. Bioengineered. 2022. PMID: 35081869 Free PMC article.
Molecular mechanism experiments exhibited that circ_0006677 functioned as a miR-1245a sponge and mediated SATB2 expression through adsorbing miR-1245a. Either miR-1245a overexpression or SATB2 knockdown weakened circ_0006677 overexpressio …
Molecular mechanism experiments exhibited that circ_0006677 functioned as a miR-1245a sponge and mediated SATB2 expression thr …
MicroRNAs as Quality Assessment Tool in Stored Packed Red Blood Cell in Blood Banks.
Mulatie Z, Aynalem M, Getawa S. Mulatie Z, et al. J Blood Med. 2023 Feb 8;14:99-106. doi: 10.2147/JBM.S397139. eCollection 2023. J Blood Med. 2023. PMID: 36789373 Free PMC article. Review.
During long storage of RBCs, miR-16-2-3p, miR-1260a, miR-1260b, miR-4443, miR-4695-3p, miR-5100, let-7b, miR-16, miRNA-1246, MiR-31-5p, miR-203a, miR-654-3p, miR-769-3p, miR-4454, miR-451a and miR-125b- 5p are up regulated. However, miR-96, miR-150, miR-196a, miR-197, miR-381 and …
During long storage of RBCs, miR-16-2-3p, miR-1260a, miR-1260b, miR-4443, miR-4695-3p, miR-5100, let-7b, miR-16, miRNA-1246, MiR-31-5p, miR- …
Validation of a Novel Cuproptosis-Related Prognostic Gene Marker and Differential Expression Associated with Lung Adenocarcinoma.
Liu T, Wei J. Liu T, et al. Curr Issues Mol Biol. 2023 Oct 22;45(10):8502-8518. doi: 10.3390/cimb45100536. Curr Issues Mol Biol. 2023. PMID: 37886979 Free PMC article.
Patients with DbetaH up-expression have a longer survival time and patients with UBE2D3, SOD1, UBE2D1 and LOXL2 down-expression also have a longer survival time. hsa-miR-29c-3p, hsa-miR-29a-3p, hsa-miR-181c-5p, hsa-miR-1245a, etc., play an important role in the miRN …
Patients with DbetaH up-expression have a longer survival time and patients with UBE2D3, SOD1, UBE2D1 and LOXL2 down-expression also have a …
Expression and Bioinformatics Analysis of Key miRNAs in Stored Red Blood Cells.
Jian F, Peng Y, Bian M. Jian F, et al. Transfus Med Hemother. 2022 Mar 28;49(5):298-305. doi: 10.1159/000522102. eCollection 2022 Sep. Transfus Med Hemother. 2022. PMID: 37969864 Free PMC article.
Furthermore, the PPI network of target genes was constructed by the STRING database, and the module analysis was carried out. RESULTS: We found two differential miRNAs, which were hsa-miR-1245a and hsa-miR-381. Enrichment analysis of GO and KEGG pathways confirmed t …
Furthermore, the PPI network of target genes was constructed by the STRING database, and the module analysis was carried out. RESULTS: We fo …
Development of a Novel Six-miRNA-Based Model to Predict Overall Survival Among Colon Adenocarcinoma Patients.
Rong Z, Rong Y, Li Y, Zhang L, Peng J, Zou B, Zhou N, Pan Z. Rong Z, et al. Front Oncol. 2020 Feb 21;10:26. doi: 10.3389/fonc.2020.00026. eCollection 2020. Front Oncol. 2020. PMID: 32154160 Free PMC article.
Finally, we found that the five miRNAs except miR-152 were upregulated in tumor tissues and CA cells. The functional experiments revealed that miR-1245a, miR-3682, miR-33b, and miR-5683 promoted the migratory abilities and proliferation of CA cell, whereas miR-152 s …
Finally, we found that the five miRNAs except miR-152 were upregulated in tumor tissues and CA cells. The functional experiments revealed th …