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Year Number of Results
2013 4
2014 10
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2017 38
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2023 91
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583 results

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miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
Wu L, Tian X, Zuo H, Zheng W, Li X, Yuan M, Tian X, Song H. Wu L, et al. J Nanobiotechnology. 2022 Apr 22;20(1):196. doi: 10.1186/s12951-022-01407-8. J Nanobiotechnology. 2022. PMID: 35459211 Free PMC article.
In vitro, inhibition of ferroptosis by HM-exos reduced hepatocyte injury. HM-exos contained more abundant miR-124-3p, which reduced ferroptosis of H/R-treated cells by inhibiting prostate six transmembrane epithelial antigen 3 (STEAP3), while overexpression o …
In vitro, inhibition of ferroptosis by HM-exos reduced hepatocyte injury. HM-exos contained more abundant miR-124-3p, w …
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
Liang L, Wo C, Yuan Y, Cao H, Tan W, Zhou X, Wang D, Chen R, Shi M, Zhang F, Xiao Y, Liu L, Zhou Y, Zhang T, Wang Y, Guo B. Liang L, et al. FASEB J. 2023 Mar;37(3):e22794. doi: 10.1096/fj.202201202RR. FASEB J. 2023. PMID: 36753399
Decreased expression of miR-124-3p was found in db/db mice compared to db/m mice. Moreover, miR-124-3p down-regulated FOXQ1 by targeting FOXQ1 mRNA 3'-UTR in NRK-52E cells. ...Conversely, the knockdown of the FOXQ1 gene induced Sirt4 expr …
Decreased expression of miR-124-3p was found in db/db mice compared to db/m mice. Moreover, miR-124-3p …
miR-23b-3p, miR-124-3p and miR-218-5p Synergistic or Additive Effects on Cellular Processes That Modulate Cervical Cancer Progression? A Molecular Balance That Needs Attention.
Romero-López MJ, Jiménez-Wences H, Cruz-De la Rosa MI, Román-Fernández IV, Fernández-Tilapa G. Romero-López MJ, et al. Int J Mol Sci. 2022 Nov 4;23(21):13551. doi: 10.3390/ijms232113551. Int J Mol Sci. 2022. PMID: 36362337 Free PMC article. Review.
In cervical cancer (CC), miR-23b-3p, miR-124-3p, and miR-218-5p have been found to act as tumor suppressors by regulating cellular processes related to progression and metastasis. The objective of the present review is to provide an update on the experimental …
In cervical cancer (CC), miR-23b-3p, miR-124-3p, and miR-218-5p have been found to act as tumor suppressors by regulati …
The potential role of miR-124-3p in tumorigenesis and other related diseases.
Li Q, Liu S, Yan J, Sun MZ, Greenaway FT. Li Q, et al. Mol Biol Rep. 2021 Apr;48(4):3579-3591. doi: 10.1007/s11033-021-06347-4. Epub 2021 Apr 20. Mol Biol Rep. 2021. PMID: 33877528 Review.
To lay the groundwork for future therapeutic strategies, in this review we mainly focus on the most recent years of literature on the functions of miR-124-3p in related major cancers, as well as its downstream target genes. Although current work as yet provid …
To lay the groundwork for future therapeutic strategies, in this review we mainly focus on the most recent years of literature on the functi …
MiR-124-3p inhibits tumor progression in prostate cancer by targeting EZH2.
Song BF, Xu LZ, Jiang K, Cheng F. Song BF, et al. Funct Integr Genomics. 2023 Mar 8;23(2):80. doi: 10.1007/s10142-023-00991-8. Funct Integr Genomics. 2023. PMID: 36884182 Free PMC article.
EZH2 and miR-124-3p expression levels were measured in PCa tissues. PCa cell lines DU145 and PC3 were transfected with miR-124-3p inhibitors or analogs. ...Overexpression of miR-124-3p decreased the phosphorylation le …
EZH2 and miR-124-3p expression levels were measured in PCa tissues. PCa cell lines DU145 and PC3 were transfected with …
MiR-124-3p targeting PDE4B attenuates LPS-induced ALI through the TLR4/NF-kappaB signaling pathway.
Zhou Q, He DX, Deng YL, Wang CL, Zhang LL, Jiang FM, Irakoze L, Liang ZA. Zhou Q, et al. Int Immunopharmacol. 2022 Apr;105:108540. doi: 10.1016/j.intimp.2022.108540. Epub 2022 Jan 18. Int Immunopharmacol. 2022. PMID: 35063752
RESULTS: We found that miR-124-3p was downregulated in LPS-induced ALI. Overexpression of miR-124-3p alleviated lung injury by inhibiting the Toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-kappaB) signaling pathway. Furthermore, w …
RESULTS: We found that miR-124-3p was downregulated in LPS-induced ALI. Overexpression of miR-124-3p …
MiR-124-3p reduces angiotensin II-dependent hypertension by down-regulating EGR1.
Lv L, Shen J, Xu J, Wu X, Zeng C, Lin L, Mao W, Wei T. Lv L, et al. J Hum Hypertens. 2021 Aug;35(8):696-708. doi: 10.1038/s41371-020-0381-x. Epub 2020 Jul 24. J Hum Hypertens. 2021. PMID: 32709884
Finally, the rescue experiments were conducted to explore the mechanism of miR-124-3p to reduce hypertension. MiR-124-3p was underexpressed in the cell model. ...MiR-124-3p inhibits Ang II-induced apoptosis and ROS pr …
Finally, the rescue experiments were conducted to explore the mechanism of miR-124-3p to reduce hypertension. MiR …
MiR-124-3p attenuates brain microvascular endothelial cell injury in vitro by promoting autophagy.
Zhao J, Wang Y, Wang D, Yan W, Zhang S, Li D, Han Z, Chen F, Lei P. Zhao J, et al. Histol Histopathol. 2022 Feb;37(2):159-168. doi: 10.14670/HH-18-406. Epub 2021 Dec 13. Histol Histopathol. 2022. PMID: 34897628
Based upon these results, the present study was formulated to examine the impact of miR-124-3p on BMVEC function and to evaluatethe mechanistic basis for its activity by overexpressing miR-124-3p in these endothelial cells. ...Lipofectami …
Based upon these results, the present study was formulated to examine the impact of miR-124-3p on BMVEC function and to …
miR-124-3p relieves allergic rhinitis by inhibiting dipeptidyl peptidase-4.
Zhang S, Dong D, Zhang Y, Wang J, Liu L, Zhao Y. Zhang S, et al. Int Immunopharmacol. 2021 Dec;101(Pt B):108279. doi: 10.1016/j.intimp.2021.108279. Epub 2021 Oct 26. Int Immunopharmacol. 2021. PMID: 34715574
MicroRNA-124-3p (miR-124-3p) and dipeptidyl peptidase-4 (DPP4) are closely related to the development of inflammation. ...Downregulation of miR-124-3p has the opposite effect. Therefore, the miR-124-3p /DPP4 axis may …
MicroRNA-124-3p (miR-124-3p) and dipeptidyl peptidase-4 (DPP4) are closely related to the development of inflammation. …
MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson's disease.
Esteves M, Abreu R, Fernandes H, Serra-Almeida C, Martins PAT, Barão M, Cristóvão AC, Saraiva C, Ferreira R, Ferreira L, Bernardino L. Esteves M, et al. Mol Ther. 2022 Oct 5;30(10):3176-3192. doi: 10.1016/j.ymthe.2022.06.003. Epub 2022 Jun 9. Mol Ther. 2022. PMID: 35689381 Free PMC article.
Here, we used umbilical cord blood mononuclear cell-derived extracellular vesicles as a biological vehicle to deliver microRNA (miR)-124-3p and evaluate its therapeutic effects in a mouse model of Parkinson's disease. ...Our findings reveal a novel promising …
Here, we used umbilical cord blood mononuclear cell-derived extracellular vesicles as a biological vehicle to deliver microRNA (miR)- …
583 results