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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1957 2
1968 1
1971 1
1974 1
1975 1
1976 5
1977 2
1978 3
1979 3
1980 2
1981 12
1982 9
1983 27
1984 26
1985 19
1986 18
1987 9
1988 5
1989 14
1990 9
1991 7
1992 2
1993 20
1994 19
1995 16
1996 17
1997 15
1998 13
1999 36
2000 36
2001 50
2002 59
2003 68
2004 67
2005 91
2006 106
2007 105
2008 101
2009 122
2010 160
2011 179
2012 176
2013 201
2014 178
2015 183
2016 158
2017 177
2018 176
2019 190
2020 205
2021 246
2022 264
2023 240
2024 97

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3,484 results

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The following term was not found in PubMed: ENSG00000182752
Page 1
Pregnancy-associated plasma protein-A (PAPPA) promotes breast cancer progression.
Zhang J, Zhang Y, Li L, Nian Y, Chen Y, Shen R, Ma X. Zhang J, et al. Bioengineered. 2022 Jan;13(1):291-307. doi: 10.1080/21655979.2021.2000724. Bioengineered. 2022. PMID: 34974815 Free PMC article.
Next, the functional role of PAPPA in breast cancer cells was validated by overexpression and knockdown experiments. ...Our study revealed that PAPPA was upregulated in PABC tissues and breast cancer cells. Overexpression of PAPPA promoted cell proliferation, …
Next, the functional role of PAPPA in breast cancer cells was validated by overexpression and knockdown experiments. ...Our study rev …
PAPP-A and the IGF system.
Monget P, Oxvig C. Monget P, et al. Ann Endocrinol (Paris). 2016 Jun;77(2):90-6. doi: 10.1016/j.ando.2016.04.015. Epub 2016 May 5. Ann Endocrinol (Paris). 2016. PMID: 27155776 Review.
Brain-specific PAPP-A knock-out mice?
Bale LK, West SA, Conover CA. Bale LK, et al. Exp Gerontol. 2021 Oct 15;154:111548. doi: 10.1016/j.exger.2021.111548. Epub 2021 Sep 9. Exp Gerontol. 2021. PMID: 34509589 Free PMC article.
PAPPA Expression in Indeterminate Thyroid Nodules as Screening Test to Select Patients for Molecular Testing.
Marzocchi C, Cantara S, Sagnella A, Castagna MG. Marzocchi C, et al. Int J Mol Sci. 2022 Apr 22;23(9):4648. doi: 10.3390/ijms23094648. Int J Mol Sci. 2022. PMID: 35563038 Free PMC article.
Pregnancy-associated plasma protein A (PAPPA) acts as an oncogene, and its expression is increased in multiple malignancies, including thyroid cancer. ...We found that the PAPPA expression increased and showed an elevated sensitivity (97.14%) and negative predictive …
Pregnancy-associated plasma protein A (PAPPA) acts as an oncogene, and its expression is increased in multiple malignancies, includin …
Circ-CHFR modulates the proliferation, migration, and invasion of ox-LDL-induced human aorta vascular smooth muscle cells through the miR-214-3p/PAPPA axis.
Lu Q, Li Y, Lou J, Li P, Gu Y, Wang X. Lu Q, et al. Clin Hemorheol Microcirc. 2022;80(4):399-412. doi: 10.3233/CH-211288. Clin Hemorheol Microcirc. 2022. PMID: 34842180
Mechanistically, circ-CHFR acted as a miR-214-3p sponge, and miR-214-3p was a molecular mediator of circ-CHFR regulation in ox-LDL-stimulated HA-VSMCs. PAPPA was a miR-214-3p target, and circ-CHFR regulated the expression of PAPPA by sponging miR-214-3p. Moreover, o …
Mechanistically, circ-CHFR acted as a miR-214-3p sponge, and miR-214-3p was a molecular mediator of circ-CHFR regulation in ox-LDL-stimulate …
PAPP-A in cardiac and non-cardiac conditions.
Li Y, Zhou C, Zhou X, Song L, Hui R. Li Y, et al. Clin Chim Acta. 2013 Feb 18;417:67-72. doi: 10.1016/j.cca.2012.12.006. Epub 2012 Dec 20. Clin Chim Acta. 2013. PMID: 23262366 Review.
m(6)A mRNA methylation regulates the ERK/NF-kappaB/AKT signaling pathway through the PAPPA/IGFBP4 axis to promote proliferation and tumor formation in endometrial cancer.
Ruan P, Wang S, Yang C, Huang X, Sun P, Tan A. Ruan P, et al. Cell Biol Toxicol. 2023 Aug;39(4):1611-1626. doi: 10.1007/s10565-022-09751-z. Epub 2022 Aug 15. Cell Biol Toxicol. 2023. PMID: 35971034
Knockdown of PAPPA or overexpression of IGFBP4 in endometrial cancer cells partially reduced disease progression caused by reduced m(6)A methylation. ...METTL3 expressed modestly and m(6)A methylation of IGFBP4 and PAPPA mRNAs decreased in endometrial cancer; 2. YTH …
Knockdown of PAPPA or overexpression of IGFBP4 in endometrial cancer cells partially reduced disease progression caused by reduced m( …
Pregnancy-associated plasma protein a in cancer: expression, oncogenic functions and regulation.
Guo Y, Bao Y, Guo D, Yang W. Guo Y, et al. Am J Cancer Res. 2018 Jun 1;8(6):955-963. eCollection 2018. Am J Cancer Res. 2018. PMID: 30034934 Free PMC article. Review.
Pregnancy-associated plasma protein A (PAPPA) is a protease that plays important roles in pregnancy, but interestingly acts as an oncogene outside of pregnancy. ...Therefore, PAPPA could be used as a biomarker for monitoring cancer development and progression as wel …
Pregnancy-associated plasma protein A (PAPPA) is a protease that plays important roles in pregnancy, but interestingly acts as an onc …
3,484 results