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The following term was not found in PubMed: ENSG00000138668
Page 1
Did you mean ENSG00000138668 OR hnrnp (8,296 results)?
METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes.
Song H, Feng X, Zhang H, Luo Y, Huang J, Lin M, Jin J, Ding X, Wu S, Huang H, Yu T, Zhang M, Hong H, Yao S, Zhao Y, Zhang Z. Song H, et al. Autophagy. 2019 Aug;15(8):1419-1437. doi: 10.1080/15548627.2019.1586246. Epub 2019 Mar 17. Autophagy. 2019. PMID: 30870073 Free PMC article.
Mechanistically, METTL3 methylates TFEB, a master regulator of lysosomal biogenesis and autophagy genes, at two m(6)A residues in the 3'-UTR, which promotes the association of the RNA-binding protein HNRNPD with TFEB pre-mRNA and subsequently decreases the expression level …
Mechanistically, METTL3 methylates TFEB, a master regulator of lysosomal biogenesis and autophagy genes, at two m(6)A residues in the 3'-UTR …
The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.
Hu H, Zhang H, Xing Y, Zhou Y, Chen J, Li C, Xu J, Guo Y, Wang J, He Q, Liu X, Sheng J, Song E, Wu Y, Huang H. Hu H, et al. Oncogene. 2022 Dec;41(49):5298-5314. doi: 10.1038/s41388-022-02495-4. Epub 2022 Nov 3. Oncogene. 2022. PMID: 36329124
Functionally, THOR knockdown impaired cell proliferation, migration and invasion in BRCA cells in vitro and inhibited tumorigenesis and metastasis in a tumor xenograft model and THOR-deficient MMTV-PyMT model in vivo. Mechanistically, THOR bound to the hnRNPD protein and i …
Functionally, THOR knockdown impaired cell proliferation, migration and invasion in BRCA cells in vitro and inhibited tumorigenesis and meta …
NFkappaB (RelA) mediates transactivation of hnRNPD in oral cancer cells.
Kumar V, Kumar A, Kumar M, Lone MR, Mishra D, Chauhan SS. Kumar V, et al. Sci Rep. 2022 Apr 8;12(1):5944. doi: 10.1038/s41598-022-09963-7. Sci Rep. 2022. PMID: 35396527 Free PMC article.
We previously demonstrated a strong association of hnRNPD over expression with poor outcome in Oral Squamous Cell Carcinoma (OSCC). ...Therefore, in an attempt to elucidate the transcriptional regulation of hnRNPD expression, we cloned 1406 bp of 5' flanking region …
We previously demonstrated a strong association of hnRNPD over expression with poor outcome in Oral Squamous Cell Carcinoma (OSCC). . …
A Mammalian Conserved Circular RNA CircLARP1B Regulates Hepatocellular Carcinoma Metastasis and Lipid Metabolism.
Li J, Wang X, Shi L, Liu B, Sheng Z, Chang S, Cai X, Shan G. Li J, et al. Adv Sci (Weinh). 2024 Jan;11(2):e2305902. doi: 10.1002/advs.202305902. Epub 2023 Nov 12. Adv Sci (Weinh). 2024. PMID: 37953462 Free PMC article.
Multiple lines of evidence demonstrate that circLARP1B binds to heterogeneous nuclear ribonucleoprotein D (HNRNPD) in the cytoplasm, and thus affects the binding of HNRNPD to sensitive transcripts including liver kinase B1 (LKB1) mRNA. ...Antisense oligodeoxynucleot …
Multiple lines of evidence demonstrate that circLARP1B binds to heterogeneous nuclear ribonucleoprotein D (HNRNPD) in the cytoplasm, …
Sodium salicylate reduced mRNA abundance of hypoxia-associated genes in MAC-T cells.
Ylioja CM, Swartz TH, Mamedova LK, Bradford BJ. Ylioja CM, et al. JDS Commun. 2021 Mar 26;2(3):159-164. doi: 10.3168/jdsc.2020-0037. eCollection 2021 May. JDS Commun. 2021. PMID: 36339495 Free PMC article.
Additionally, cells were transfected with either HIF1A small interfering RNA (siRNA) or a scrambled siRNA negative control 48 h before hypoxia treatments. HIF1A, GLUT1, VEGFA, and HNRNPD were quantified relative to the internal control gene NENF. ...Hypoxia increased GLUT1 …
Additionally, cells were transfected with either HIF1A small interfering RNA (siRNA) or a scrambled siRNA negative control 48 h before hypox …
Evaluation of Heterogeneous Nuclear Ribonucleoprotein D Expression as a Diagnostic Marker for Oral Squamous Cell Carcinoma.
Kumar V, Lone MR, Kumar A, Vincent V, Thakkar H, Mishra D, Chauhan SS. Kumar V, et al. Diagnostics (Basel). 2022 May 27;12(6):1332. doi: 10.3390/diagnostics12061332. Diagnostics (Basel). 2022. PMID: 35741145 Free PMC article.
The poorly differentiated squamous cell carcinoma displayed 100% (eight cases) immunoreactivity for hnRNPD as compared to 87.5% (seven cases) for p40. Nuclear staining of p40 and hnRNPD was observed in all OSCC specimens. p40 staining was restricted to basal cells, …
The poorly differentiated squamous cell carcinoma displayed 100% (eight cases) immunoreactivity for hnRNPD as compared to 87.5% (seve …
RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts.
Kattan FG, Koukouraki P, Anagnostopoulos AK, Tsangaris GT, Doxakis E. Kattan FG, et al. Open Biol. 2023 Nov;13(11):230158. doi: 10.1098/rsob.230158. Epub 2023 Nov 22. Open Biol. 2023. PMID: 37989221 Free PMC article.
Mass spectrometry of proteins pulled down from murine brain lysates using a biotinylated SNCA 3'UTR revealed multiple RNA-binding proteins, of which HNRNPD/AUF1 was chosen for further analysis. AUF1 bound both proximal and distal regions of the SNCA 3'UTR, but not the 5'UT …
Mass spectrometry of proteins pulled down from murine brain lysates using a biotinylated SNCA 3'UTR revealed multiple RNA-binding proteins, …
HNRNPD is a prognostic biomarker in non-small cell lung cancer and affects tumor growth and metastasis via the PI3K-AKT pathway.
Fan G, Li D, Liu J, Tao N, Meng C, Cui J, Cai J, Sun T. Fan G, et al. Biotechnol Genet Eng Rev. 2023 Mar 27:1-20. doi: 10.1080/02648725.2023.2196155. Online ahead of print. Biotechnol Genet Eng Rev. 2023. PMID: 36971333
Heterogeneous nuclear ribonucleoprotein D (HNRNPD) can regulate expression of key proteins in various cancers. However, the prognostic predictive value and biology function of HNRNPD in non-small cell lung cancer (NSCLC) is unknown. First, we used the TCGA and GEO d …
Heterogeneous nuclear ribonucleoprotein D (HNRNPD) can regulate expression of key proteins in various cancers. However, the prognosti …
The expression and biological effect of NR2F6 in non-small cell lung cancer.
Yang SL, Guan HQ, Yang HB, Chen Y, Huang XY, Chen L, Shen ZF, Wang LX. Yang SL, et al. Front Oncol. 2022 Sep 2;12:940234. doi: 10.3389/fonc.2022.940234. eCollection 2022. Front Oncol. 2022. PMID: 36119482 Free PMC article.
The impact of HNRNPD knockdown on the proliferation capacity of lung cancer cells was verified at cell level, and the relationship between NR2F6 and HNRNPD was verified by co-immunoprecipitation. ...Knockdown of HNRNPD also inhibited the proliferation of lung …
The impact of HNRNPD knockdown on the proliferation capacity of lung cancer cells was verified at cell level, and the relationship be …
LncRNA MRF drives the regulatory function on monocyte recruitment and polarization through HNRNPD-MCP1 axis in mesenchymal stem cells.
Lin J, Xie Z, Zhang Z, Li M, Ye G, Yu W, Li J, Ye F, Su Z, Che Y, Xu P, Zeng C, Wang P, Wu Y, Shen H. Lin J, et al. J Biomed Sci. 2022 Sep 21;29(1):73. doi: 10.1186/s12929-022-00858-3. J Biomed Sci. 2022. PMID: 36127734 Free PMC article.
Mechanistically, MRF bound to the downstream protein heterogeneous nuclear ribonucleoprotein D (HNRNPD) to upregulate MCP1 expression, and the transcription factor interferon regulatory factor 1 (IRF1) activated MRF transcription early during coculture. ...MRF regulates th …
Mechanistically, MRF bound to the downstream protein heterogeneous nuclear ribonucleoprotein D (HNRNPD) to upregulate MCP1 expression …
332 results