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The following term was not found in PubMed: ENSG00000124140
Page 1
Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain.
Li J, Tian M, Hua T, Wang H, Yang M, Li W, Zhang X, Yuan H. Li J, et al. Autophagy. 2021 Dec;17(12):4062-4082. doi: 10.1080/15548627.2021.1900498. Epub 2021 Apr 9. Autophagy. 2021. PMID: 33834930 Free PMC article.
Our study provides an underlying mechanism by which autophagy participates in the regulation of neuropathic pain, and a combination of autophagy and NFE2L2 activation may be a new treatment approach for neuropathic pain.Abbreviation: 3-MA: 3-methyladenine; 8-OHdG: 8-hydroxydeoxy- …
Our study provides an underlying mechanism by which autophagy participates in the regulation of neuropathic pain, and a combination of autop …
SLC12A5-Related Epilepsy of Infancy with Migrating Focal Seizures.
McTague A, Kurian MA. McTague A, et al. 2019 Feb 14. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2019 Feb 14. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 30763027 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: SLC12A5-related epilepsy of infancy with migrating focal seizures (SLC12A5-EIMFS), reported to date in nine children, is characterized by onset of seizures before age six months and either developmental delay or developmental regression wit …
CLINICAL CHARACTERISTICS: SLC12A5-related epilepsy of infancy with migrating focal seizures (SLC12A5-EIMFS), reported to date …
SLC12A5 promotes hepatocellular carcinoma growth and ferroptosis resistance by inducing ER stress and cystine transport changes.
Tong Q, Qin W, Li ZH, Liu C, Wang ZC, Chu Y, Xu XD. Tong Q, et al. Cancer Med. 2023 Apr;12(7):8526-8541. doi: 10.1002/cam4.5605. Epub 2023 Jan 16. Cancer Med. 2023. PMID: 36645171 Free PMC article.
However, the effects of SLC12A5 in HCC have not been determined. METHODS: SLC12A5 expression was assessed by immunostaining and western blotting. ...Subcutaneous tumor formation experiments were used to validate the tumorigenic effect of SLC12A5 in vivo. RNA- …
However, the effects of SLC12A5 in HCC have not been determined. METHODS: SLC12A5 expression was assessed by immunostaining an …
A potassium-chloride co-transporter promotes tumor progression and castration resistance of prostate cancer through m6A reader YTHDC1.
Yuan S, He SH, Li LY, Xi S, Weng H, Zhang JH, Wang DQ, Guo MM, Zhang H, Wang SY, Ming DJ, Liu MY, Hu H, Zeng XT. Yuan S, et al. Cell Death Dis. 2023 Jan 6;14(1):7. doi: 10.1038/s41419-022-05544-8. Cell Death Dis. 2023. PMID: 36609444 Free PMC article.
SLC12A5, a neuron-specific potassium-chloride co-transporter, has been reported to promote tumor progression, however, the underlying mechanism remains unclear. ...Therefore, our findings reveal a mechanism that how the potassium-chloride cotransporter SLC12A5 promo …
SLC12A5, a neuron-specific potassium-chloride co-transporter, has been reported to promote tumor progression, however, the underlying …
A Pan-Cancer Analysis of SLC12A5 Reveals Its Correlations with Tumor Immunity.
Jiang Y, Liao HL, Chen LY. Jiang Y, et al. Dis Markers. 2021 Sep 29;2021:3062606. doi: 10.1155/2021/3062606. eCollection 2021. Dis Markers. 2021. PMID: 34630736 Free PMC article.
BACKGROUND: Solute carrier family 12 member 5 (SLC12A5) has been reported to play an oncogenic role in certain malignancies. ...RESULTS: Herein, we observed that SLC12A5 was significantly overexpressed in various malignancies, and SLC12A5 levels correlated wi …
BACKGROUND: Solute carrier family 12 member 5 (SLC12A5) has been reported to play an oncogenic role in certain malignancies. ...RESUL …
Pathogenic potential of human SLC12A5 variants causing KCC2 dysfunction.
Fukuda A, Watanabe M. Fukuda A, et al. Brain Res. 2019 May 1;1710:1-7. doi: 10.1016/j.brainres.2018.12.025. Epub 2018 Dec 18. Brain Res. 2019. PMID: 30576625 Free article. Review.
SLC12A5 encodes K(+)-Cl(-) cotransporter 2 (KCC2), which is the main Cl(-) extruder of neurons, and renders the proper inhibitory function of the neurotransmitters gamma-aminobutyric acid (GABA) and glycine. ...Thus, it is clear that the loss-of-function variants of human …
SLC12A5 encodes K(+)-Cl(-) cotransporter 2 (KCC2), which is the main Cl(-) extruder of neurons, and renders the proper inhibitory fun …
Overexpression of SLC12A5 is associated with tumor progression and poor survival in ovarian carcinoma.
Yang GP, He WP, Tan JF, Yang ZX, Fan RR, Ma NF, Wang FW, Chen L, Li Y, Shen HW, You ZS, Xie D, Yang GF. Yang GP, et al. Int J Gynecol Cancer. 2019 Oct;29(8):1280-1284. doi: 10.1136/ijgc-2019-000229. Int J Gynecol Cancer. 2019. PMID: 31570543
INTRODUCTION: The solute carrier family 12 member 5 (SLC12A5) gene is playing a putative oncogenic role in colorectal carcinoma. ...A subsequent univariate survival analysis of our ovarian carcinoma cohorts resulted in a significant association between SLC12A5 prote …
INTRODUCTION: The solute carrier family 12 member 5 (SLC12A5) gene is playing a putative oncogenic role in colorectal carcinoma. ...A …
SLC12A5 interacts and enhances SOX18 activity to promote bladder urothelial carcinoma progression via upregulating MMP7.
Wang L, Zhang Q, Wu P, Xiang W, Xie D, Wang N, Deng M, Cao K, Zeng H, Xu Z, Xiaoming Liu, He L, Long Z, Tan J, Wang J, Liu B, Liu J. Wang L, et al. Cancer Sci. 2020 Jul;111(7):2349-2360. doi: 10.1111/cas.14502. Epub 2020 Jun 13. Cancer Sci. 2020. PMID: 32449280 Free PMC article.
Solute carrier family 12 member 5 (SLC12A5) has an oncogenic role in bladder urothelial carcinoma. The present study aimed to characterize the molecular mechanisms of SLC12A5 in bladder urothelial carcinoma pathogenesis. ...Furthermore, SLC12A5 expression was …
Solute carrier family 12 member 5 (SLC12A5) has an oncogenic role in bladder urothelial carcinoma. The present study aimed to charact …
157 results