[Hemostasis using vasopressin analogs during conization of the uterine cervix and minor vaginal operations]

Ceska Gynekol. 1997 Jun;62(3):142-4.
[Article in Czech]

Abstract

Peroperative haemorrhage is a frequent complication of conization of the portio uteri by surgery-by a "cold knife" scalpel or another method (LEEP, laser, etc.). In a clinical study comprising 41 patients with the diagnosis CIN I-III or laceration of the portio uteri classical conization by means of a scalpel was made with concurrent haemostasis with terlipressin (TLP) by paracervical administration (400 micrograms-REMESTYP 2 amp.). Concurrently the blood loss in ml was followed, the Hb level and other effects of the preparation. From the results ensues that side-effects after local administration of TLP were observed only in 12.2%. Peroperative blood losses were on average under 15 ml. Local paracervical TLP administration appears effective from the clinical aspect with regard to the low frequency of side-effects and the favourable haemostatic effect.

MeSH terms

  • Blood Loss, Surgical / prevention & control*
  • Cervix Uteri / surgery*
  • Conization*
  • Female
  • Hemostasis, Surgical
  • Humans
  • Lypressin / administration & dosage
  • Lypressin / analogs & derivatives*
  • Terlipressin
  • Uterine Cervical Dysplasia / surgery
  • Uterine Cervical Neoplasms / surgery
  • Vagina / surgery*

Substances

  • Lypressin
  • Terlipressin