Abstract
Uterine endocervix adenocarcinoma (UEA) is shown to have a structure typical for glandular carcinomas. It differs from endometrial carcinoma by cytokeratin (CK) N 17 expression, that of carcinoembryonic antigen and negative reaction to vimentin. CK N 17 found in UEA is not observed in colon and ovarian adenocarcinoma. The latter gives a positive response to vimentin. These results allow differential diagnosis of endocervix adenocarcinoma and those of colon and ovary.
MeSH terms
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Adenocarcinoma / chemistry
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Adenocarcinoma / pathology*
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Adenocarcinoma / ultrastructure
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Biomarkers, Tumor / chemistry
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Carcinoembryonic Antigen / analysis
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Diagnosis, Differential
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Endometrial Neoplasms / pathology
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Female
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Humans
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Immunohistochemistry
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Intestinal Neoplasms / pathology
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Intestine, Large / pathology
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Keratins / analysis
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Neoplasm Invasiveness
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Neoplasm Proteins / analysis
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Ovarian Neoplasms / pathology
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Uterine Cervical Neoplasms / chemistry
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Uterine Cervical Neoplasms / pathology*
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Uterine Cervical Neoplasms / ultrastructure
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Vimentin / analysis
Substances
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Biomarkers, Tumor
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Carcinoembryonic Antigen
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Neoplasm Proteins
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Vimentin
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Keratins