Low T-cell receptor excision circles (TREC) in children and adolescents with immune thrombocytopenia

Br J Haematol. 2021 Feb;192(4):e99-e102. doi: 10.1111/bjh.17289. Epub 2020 Dec 21.

Authors

Denis Santana-Santos¹, Bernadete L Liphaus¹, Julia M Beatrice², Jorge D A Carneiro², Magda M S Carneiro-Sampaio¹, Andreia Rangel-Santos¹

Affiliations

¹ Laboratory of Medical Investigation (LIM36) of Department of Pediatrics, Universidade de São Paulo, São Paulo, Brazil.
² Pediatric Hematology Unit, Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

PMID: 33348432
DOI: 10.1111/bjh.17289

No abstract available

Keywords: T-cell receptor excision circles (TREC); chronic disease; immune thrombocytopenia (ITP); immunodeficiency; pathogenesis.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Child
Child, Preschool
DNA, Circular / genetics*
DNA, Circular / immunology
Female
Humans
Male
Purpura, Thrombocytopenic, Idiopathic / genetics*
Purpura, Thrombocytopenic, Idiopathic / immunology
Receptors, Antigen, T-Cell / genetics*
Receptors, Antigen, T-Cell / immunology
T-Lymphocytes / immunology
T-Lymphocytes / metabolism
Thymus Gland / immunology
Thymus Gland / metabolism

Substances

DNA, Circular
Receptors, Antigen, T-Cell

Grants and funding