The Biofilms Structural Database

Rita P Magalhães; Tatiana F Vieira; Henrique S Fernandes; André Melo; Manuel Simões; Sérgio F Sousa

doi:10.1016/j.tibtech.2020.04.002

The Biofilms Structural Database

Trends Biotechnol. 2020 Sep;38(9):937-940. doi: 10.1016/j.tibtech.2020.04.002. Epub 2020 May 5.

Authors

Rita P Magalhães¹, Tatiana F Vieira¹, Henrique S Fernandes¹, André Melo², Manuel Simões³, Sérgio F Sousa⁴

Affiliations

¹ UCIBIO/REQUIMTE, BioSIM, Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
² LAQV/REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal.
³ LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Porto, Portugal.
⁴ UCIBIO/REQUIMTE, BioSIM, Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal. Electronic address: sergiofsousa@med.up.pt.

PMID: 32386874
DOI: 10.1016/j.tibtech.2020.04.002

Abstract

The Biofilms Structural Database (BSD) is a collection of structural, mutagenesis, kinetics, and inhibition data to understand the processes involved in biofilm formation. Presently, it includes curated information on 425 structures of proteins and enzymes involved in biofilm formation and development for 42 different bacteria. It is available at www.biofilms.biosim.pt.

Keywords: antimicrobials; bacteria; inhibition; quorum sensing; resistance.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Anti-Bacterial Agents / chemistry*
Anti-Bacterial Agents / therapeutic use
Biofilms / drug effects*
Biofilms / growth & development
Databases, Factual*
Kinetics
Mutagenesis / drug effects*
Mutagenesis / genetics
Quorum Sensing / drug effects
Quorum Sensing / genetics

Substances

Anti-Bacterial Agents