Advanced Glycation End Products in Chinese Medicine Mediated Aging Diseases: A Review

Curr Vasc Pharmacol. 2020;18(4):322-333. doi: 10.2174/1570161117666190507112157.

Abstract

Aging has become a worldwide problem. During this process, the incidence of related diseases such as diabetes and atherosclerosis increases dramatically. Studies within the most recent two decades suggest a pivotal role of Advanced Glycation End Products (AGEs) in the aging process. This review aims to systemically summarize the effects and potential mechanism of Chinese Medicines on inhibiting AGEs-related aging diseases.

Keywords: Aging; Alzheimer's disease; Chinese medicines; advanced glycation end products; diabetes; vascular diseases..

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Age Factors
  • Aging / drug effects*
  • Aging / metabolism
  • Aging / pathology
  • Animals
  • Apoptosis / drug effects
  • Drugs, Chinese Herbal / adverse effects
  • Drugs, Chinese Herbal / therapeutic use*
  • Energy Metabolism / drug effects
  • Glycation End Products, Advanced / antagonists & inhibitors*
  • Glycation End Products, Advanced / metabolism
  • Humans
  • Inflammation Mediators / metabolism
  • Medicine, Chinese Traditional* / adverse effects
  • Noncommunicable Diseases / drug therapy*
  • Noncommunicable Diseases / epidemiology
  • Oxidative Stress / drug effects
  • Risk Factors
  • Signal Transduction

Substances

  • Drugs, Chinese Herbal
  • Glycation End Products, Advanced
  • Inflammation Mediators