Long-Term Opioid Agonist Treatment Participation after First Treatment Entry is Similar across 4 European Regions but Lower in Non-Nationals

Eur Addict Res. 2018;24(4):173-183. doi: 10.1159/000490529. Epub 2018 Jul 17.

Abstract

Heroin users in opioid agonist treatment (OAT) show markedly reduced heroin consumption, less crime and a lower mortality rate. However, the extent of long-term OAT participation over subsequent treatment episodes remains unclear. We analysed the annual proportion of patients in treatment (at least 1 day) since the start of first OAT in 4 European regions: Barcelona (BA) 1996-2012: 8,602 patients; Czech -Republic (CZ) 2000-2014: 4,377 patients; Netherlands (NL) 1994-2014: 33,235 patients, Zurich (ZU) 1992-2015: 11,795. We estimated the long-term decline of treatment need due to mortality or abstinence and also a "nuisance" short-term decline until the equilibrium level of cycling in and out of OAT is reached to obtain the adjusted treatment participation value. The adjusted treatment participation was around 50% (BA: 47.4-51.4%; CZ: 49.8-53.9%; NL: 52.3-54.0%; ZU: 46.4-49.3%), and the annual decline of treatment need was close to 4%. Non-nationals (NL patients with a migrant background) showed substantial lower adjusted treatment participation (rate ratio BA: 0.059-0.343; NL: 0.710-0.751; ZU: 0.681-0.797; CZ: n.a.). Our method may provide a policy-relevant indicator of long-term provision, quality and access to OAT following first treatment.

Keywords: Buprenorphine; Drug policy; Heroin; Methadone; Opioids; Public health; Treatment monitoring.

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage*
  • Czech Republic / epidemiology
  • Databases, Factual / trends
  • Drug Administration Schedule
  • Emigrants and Immigrants*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Opiate Substitution Treatment / methods
  • Opiate Substitution Treatment / trends*
  • Opioid-Related Disorders / diagnosis
  • Opioid-Related Disorders / epidemiology*
  • Opioid-Related Disorders / therapy*
  • Patient Participation / methods
  • Patient Participation / trends*
  • Spain / epidemiology
  • Switzerland / epidemiology
  • Treatment Outcome

Substances

  • Analgesics, Opioid