When Is It Appropriate to Put a Live Donor at Risk to Help Another Patient?

AMA J Ethics. 2018 Jun 1;20(1):537-545. doi: 10.1001/journalofethics.2018.20.6.cscm2-1806.

Abstract

This article considers the nature and scope of ethical decision making in monozygotic sibling (MZS) skin grafting. Although rare, identical twin-to-twin skin grafting has been reported with excellent survival rates in burn patients. Of 16 cases published to date, only a few address the ethical decision making process that is involved with monozygotic sibling skin grafting; this article discusses clinical indications and ethical challenges.

MeSH terms

  • Burns / surgery
  • Decision Making / ethics*
  • Donor Selection / ethics*
  • Ethics, Medical*
  • Helping Behavior
  • Humans
  • Living Donors / ethics*
  • Risk
  • Siblings*
  • Skin Transplantation / ethics*
  • Twins, Monozygotic*