Dynamic classification of fetal heart rates by hierarchical Dirichlet process mixture models

PLoS One. 2017 Sep 27;12(9):e0185417. doi: 10.1371/journal.pone.0185417. eCollection 2017.

Abstract

In this paper, we propose an application of non-parametric Bayesian (NPB) models for classification of fetal heart rate (FHR) recordings. More specifically, we propose models that are used to differentiate between FHR recordings that are from fetuses with or without adverse outcomes. In our work, we rely on models based on hierarchical Dirichlet processes (HDP) and the Chinese restaurant process with finite capacity (CRFC). Two mixture models were inferred from real recordings, one that represents healthy and another, non-healthy fetuses. The models were then used to classify new recordings and provide the probability of the fetus being healthy. First, we compared the classification performance of the HDP models with that of support vector machines on real data and concluded that the HDP models achieved better performance. Then we demonstrated the use of mixture models based on CRFC for dynamic classification of the performance of (FHR) recordings in a real-time setting.

MeSH terms

  • Bayes Theorem
  • Heart Rate, Fetal*
  • Humans
  • Models, Biological