Presence of foveal bulge in optical coherence tomographic images in eyes with macular edema associated with branch retinal vein occlusion

Am J Ophthalmol. 2014 Feb;157(2):390-396.e1. doi: 10.1016/j.ajo.2013.10.007. Epub 2013 Oct 19.

Abstract

Purpose: To determine whether a significant correlation exists between the presence of a bulge in the photoreceptor inner segment/outer segment (IS/OS) line and the best-corrected visual acuity (BCVA) in eyes with resolved macular edema associated with branch retinal vein occlusion (BRVO).

Design: Retrospective, observational case series.

Methods: We retrospectively reviewed the medical records of patients who had a complete resolution of macular edema and had an intact IS/OS line in the central fovea in the spectral-domain optical coherence tomographic (SDOCT) images. Thirty-one eyes with macular edema associated with BRVO (BRVO group) and 31 unaffected fellow eyes (control group) of 31 patients were evaluated. In normal eyes, the intact IS/OS line determined by SDOCT has a bulge at the central fovea, called the foveal bulge. The eyes in the BRVO group were classified by the presence or absence of foveal bulge, and the characteristics of the 2 groups were compared.

Results: A foveal bulge was present in 7 of 31 eyes in the BRVO group. The incidence of a foveal bulge was significantly lower in the BRVO group (22.6%) than in the control group (100%; P < .0001). All 7 eyes with foveal bulge had a decimal BCVA of ≥1.0 at the final visit. The incidence of a foveal bulge was significantly higher in eyes with BCVA of ≥1.0 (77.8%) than in the eyes with BCVA of <1.0 (0%; P < .0001).

Conclusions: The foveal bulge is a good marker of the functional properties of the fovea in eyes with resolved macular edema associated with BRVO.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Fovea Centralis / pathology*
  • Humans
  • Macular Edema / etiology
  • Macular Edema / physiopathology*
  • Male
  • Middle Aged
  • Retinal Photoreceptor Cell Inner Segment / pathology*
  • Retinal Photoreceptor Cell Outer Segment / pathology*
  • Retinal Vein Occlusion / complications*
  • Retrospective Studies
  • Tomography, Optical Coherence*
  • Visual Acuity / physiology