Objective: to study the clinical and functional changes in the biliary tract in patents with psoriasis concurrent with chronic opisthorchiasis (CO).
Subjects and methods: 60 patients with psoriasis concurrent with CO, 45 patients with psoriasis without helminthism, 30 with CO, and 15 healthy individuals were examined. Chromatic fractional duodenal intubation, dynamic hepatobiliscintigraphy, and ultrasound study of the liver and gallbladder were used. The concentrations of cholesterol, bile acids, bilirubin, total lipids and phospholipids in bile were measured. A number of relative indices, such as cholate-cholesterol coefficient (CCC), Thomas-Hofmann index, and Rubens index were calculated.
Results and discussion: The patients with psoriasis with CO were found to have signs of mainly hypermotor dyskinesia of the biliary tract, as well as increased bile lithogenicity (lower CCC, and increases in the Rubens index and Thomas-Hofmann index).
Conclusions: The clinical and functional changes found in the biliary tract of the patients with psoriasis concurrent with CO show it necessary to perform antihelminthic therapy in this group of patients.