Photoreceptor inner and outer segment defects in myopic foveoschisis

Am J Ophthalmol. 2008 May;145(5):902-8. doi: 10.1016/j.ajo.2008.01.011. Epub 2008 Mar 14.

Abstract

Purpose: To evaluate pathologic features of the photoreceptors in myopic foveoschisis with the Fourier-domain optical coherence tomography (FD-OCT).

Design: Observational case series.

Methods: Seventeen eyes of 15 patients with myopic foveoschisis (foveal detachment type, six eyes; foveoschisis type, 11 eyes) were included. We observed the photoreceptor inner and outer segments (IS/OS) and evaluated the morphologic status using FD-OCT. Fundus photographs and time-domain OCT (TD-OCT) images also were obtained.

Results: IS/OS defects, which are uncommon in retinal detachments in eyes with myopia, were seen clearly in five eyes (three eyes [50%] with the foveal detachment type; two eyes [18%] with the foveal schisis type). Fundus photographs showed myopic chorioretinal atrophy in eight study eyes (47%), including diffuse atrophy in four eyes (24%) and patchy atrophy in four eyes (24%). The IS/OS defects on FD-OCT were accompanied by myopic chorioretinal atrophy in three (60%) of five eyes.

Conclusions: FD-OCT enables observation of more detailed retinal structures in these myopic eyes. The IS/OS defects may be specific to, but are not rare, in myopic foveoschisis and may predict the postoperative visual recovery.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Female
  • Fourier Analysis
  • Humans
  • Male
  • Middle Aged
  • Myopia / complications*
  • Photoreceptor Cells, Vertebrate / pathology*
  • Retinoschisis / diagnosis*
  • Retinoschisis / etiology
  • Tomography, Optical Coherence / methods*
  • Visual Acuity