Unresponsive or non-compliant steatorrhea in cystic fibrosis?

Aleksandra Lisowska; Barbara Kaminska; Marian Grzymislawski; Karl-Heinz Herzig; Jaroslaw Walkowiak

doi:10.1016/j.jcf.2006.05.006

Unresponsive or non-compliant steatorrhea in cystic fibrosis?

J Cyst Fibros. 2006 Dec;5(4):253-5. doi: 10.1016/j.jcf.2006.05.006. Epub 2006 Jun 9.

Authors

Aleksandra Lisowska¹, Barbara Kaminska, Marian Grzymislawski, Karl-Heinz Herzig, Jaroslaw Walkowiak

Affiliation

¹ Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Szpitalna 27/33, 60-572 Poznan, Poland.

PMID: 16765107
DOI: 10.1016/j.jcf.2006.05.006

Abstract

In 105 pancreatic insufficient CF patients (steatorrhea and low fecal elastase-1 concentrations), the effectiveness of pancreatic enzyme therapy (PET) has been assessed (fecal fat losses and coefficient of fat reabsorption). Eight unresponsive subjects were checked for PET compliance with fecal chymotrypsin assay. Three patients were documented to be non-compliant. Unresponsive patients should undergo evaluation for PET compliance.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Child
Child, Preschool
Chymotrypsin / analysis
Cystic Fibrosis / complications*
Cystic Fibrosis / drug therapy*
Cystic Fibrosis / metabolism
Dietary Supplements*
Feces / chemistry
Female
Humans
Hydrolases / therapeutic use*
Male
Pancreatic Elastase / analysis
Pancreatic Function Tests
Patient Compliance
Steatorrhea / drug therapy*
Steatorrhea / etiology*
Steatorrhea / metabolism
Treatment Outcome

Substances

Hydrolases
Chymotrypsin
Pancreatic Elastase