Abstract
A chronic mucocutaneous disease was diagnosed in 3 dogs. Clinically, the disease was characterized by erosions and ulcerations of the oral mucosa, various mucocutaneous junctions, and the skin. Histologically, there was acantholysis or a separation of the epithelial cells from one another, resulting in the formation of clefts and bullae. Based on clinical and laboratory findings, the disease seemed to be the canine equivalent of pemphigus vulgaris (PV) in man.
MeSH terms
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Acantholysis / pathology
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Acantholysis / veterinary
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Anal Canal / pathology
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Animals
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Blood Urea Nitrogen
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Chloramphenicol / therapeutic use
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Desmosomes / ultrastructure
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Dog Diseases* / drug therapy
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Dog Diseases* / pathology
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Dogs
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Eyelids / pathology
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Female
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Gingiva / pathology
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Male
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Mediastinal Neoplasms / pathology
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Mediastinal Neoplasms / veterinary
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Mouth Mucosa / ultrastructure
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Pemphigus / drug therapy
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Pemphigus / pathology
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Pemphigus / veterinary*
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Prednisolone / therapeutic use
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Skin / pathology
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Thymoma / pathology
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Thymoma / veterinary
Substances
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Chloramphenicol
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Prednisolone