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2006 1
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I have most of my asthma under control and I know how my asthma acts: Users' perceptions of asthma self-management mobile app tailored for adolescents.
Schneider T, Baum L, Amy A, Marisa C. Schneider T, et al. Health Informatics J. 2020 Mar;26(1):342-353. doi: 10.1177/1460458218824734. Epub 2019 Feb 8. Health Informatics J. 2020. PMID: 30732520 Free article.
In all, 20 adolescents participated in a 3-month trial to test an asthma app tailored to their age. Qualitative data on adolescents' experience with the app were inquired. ...They indicated external factors that limited app use and suggested improvements to m …
In all, 20 adolescents participated in a 3-month trial to test an asthma app tailored to their age. Qualitative data on adolescents' …
Phosphorylation Signaling in APP Processing in Alzheimer's Disease.
Zhang T, Chen D, Lee TH. Zhang T, et al. Int J Mol Sci. 2019 Dec 27;21(1):209. doi: 10.3390/ijms21010209. Int J Mol Sci. 2019. PMID: 31892243 Free PMC article. Review.
The phosphorylation of APP and key enzymes involved in the proteolytic processing of APP has been demonstrated to be critical for modulating the generation of Abeta by either altering the subcellular localization of APP or changing the enzymatic activities of …
The phosphorylation of APP and key enzymes involved in the proteolytic processing of APP has been demonstrated to be critical …
Amyloid, APP, and Electrical Activity of the Brain.
Hefter D, Ludewig S, Draguhn A, Korte M. Hefter D, et al. Neuroscientist. 2020 Jun;26(3):231-251. doi: 10.1177/1073858419882619. Epub 2019 Nov 29. Neuroscientist. 2020. PMID: 31779518 Free PMC article. Review.
Much research on APP focusses on potential contributions to neurodegeneration, mostly based on mouse models with altered expression or mutated forms of APP. However, cumulative evidence from recent years indicates the indispensability of APP and its metabolit …
Much research on APP focusses on potential contributions to neurodegeneration, mostly based on mouse models with altered expression o …
A device and an app for the diagnosis and self-management of tinnitus.
Vittorini P, Chamoso P, De la Prieta F. Vittorini P, et al. J Integr Bioinform. 2022 Aug 30;19(3):20220004. doi: 10.1515/jib-2022-0004. eCollection 2022 Sep 1. J Integr Bioinform. 2022. PMID: 36039680 Free PMC article. Review.
The results show that automated reporting is comparable with that of physicians and that user experience was improved by re-designing and re-developing the acufenometry of the app. As for the user experience, two experts in Human-Computer Interaction evaluated the first ve …
The results show that automated reporting is comparable with that of physicians and that user experience was improved by re-designing and re …
O-GalNAc glycosylation determines intracellular trafficking of APP and Abeta production.
Tachida Y, Iijima J, Takahashi K, Suzuki H, Kizuka Y, Yamaguchi Y, Tanaka K, Nakano M, Takakura D, Kawasaki N, Saito Y, Manya H, Endo T, Kitazume S. Tachida Y, et al. J Biol Chem. 2023 Jul;299(7):104905. doi: 10.1016/j.jbc.2023.104905. Epub 2023 Jun 9. J Biol Chem. 2023. PMID: 37302553 Free PMC article.
Parenchymal amyloid plaques presumably originate from neuronal Abeta precursor protein (APP). Although vascular amyloid deposits' origins remain unclear, endothelial APP expression in APP knock-in mice was recently shown to expand CAA pathology, highlighting …
Parenchymal amyloid plaques presumably originate from neuronal Abeta precursor protein (APP). Although vascular amyloid deposits' ori …
Amyloid-Beta Mediates Homeostatic Synaptic Plasticity.
Galanis C, Fellenz M, Becker D, Bold C, Lichtenthaler SF, Müller UC, Deller T, Vlachos A. Galanis C, et al. J Neurosci. 2021 Jun 16;41(24):5157-5172. doi: 10.1523/JNEUROSCI.1820-20.2021. Epub 2021 Apr 29. J Neurosci. 2021. PMID: 33926999 Free PMC article.
The physiological role of the amyloid-precursor protein (APP) is insufficiently understood. Recent work has implicated APP in the regulation of synaptic plasticity. ...Here, we addressed the relevance of APP in homeostatic synaptic plasticity using organotypi …
The physiological role of the amyloid-precursor protein (APP) is insufficiently understood. Recent work has implicated APP in …
Polypharmacy Management of Antipsychotics in Patients with Schizophrenia.
Kamei H. Kamei H. Medicina (Kaunas). 2022 Nov 3;58(11):1584. doi: 10.3390/medicina58111584. Medicina (Kaunas). 2022. PMID: 36363541 Free PMC article. Review.
However, the risk of APP-related adverse events is high. The application of APP needs to be carefully reviewed, whilst taking into consideration patient backgrounds. ...This review discusses the merits of APP, matters that need to be considered, and a switch …
However, the risk of APP-related adverse events is high. The application of APP needs to be carefully reviewed, whilst taking …
Knockdown of Amyloid Precursor Protein: Biological Consequences and Clinical Opportunities.
Gabriele RMC, Abel E, Fox NC, Wray S, Arber C. Gabriele RMC, et al. Front Neurosci. 2022 Mar 14;16:835645. doi: 10.3389/fnins.2022.835645. eCollection 2022. Front Neurosci. 2022. PMID: 35360155 Free PMC article. Review.
People living with one copy of APP are asymptomatic and reducing APP has been shown to lower the relative production of aggregation-prone Abeta species in vitro. ...In this review, we will describe the structure and the known functions of APP and go on to dis …
People living with one copy of APP are asymptomatic and reducing APP has been shown to lower the relative production of aggreg …
APP family member dimeric complexes are formed predominantly in synaptic compartments.
Schilling S, August A, Meleux M, Conradt C, Tremmel LM, Teigler S, Adam V, Müller UC, Koo EH, Kins S, Eggert S. Schilling S, et al. Cell Biosci. 2023 Aug 2;13(1):141. doi: 10.1186/s13578-023-01092-6. Cell Biosci. 2023. PMID: 37533067 Free PMC article.
BACKGROUND: The amyloid precursor protein (APP), a key player in Alzheimer's disease (AD), is part of a larger gene family, including the APP like proteins APLP1 and APLP2. ...Interestingly, only about 20% of APP is dimerized in cultured cells whereas up to 5 …
BACKGROUND: The amyloid precursor protein (APP), a key player in Alzheimer's disease (AD), is part of a larger gene family, including …
Prone positioning of nonintubated patients with acute hypoxemic respiratory failure.
Li J, Roca O, Ehrmann S. Li J, et al. Curr Opin Crit Care. 2023 Feb 1;29(1):1-7. doi: 10.1097/MCC.0000000000001009. Epub 2022 Dec 9. Curr Opin Crit Care. 2023. PMID: 36580368 Review.
RECENT FINDINGS: Numerous clinical studies have been conducted to investigate the effects of APP on oxygenation, intubation, and mortality. However, several questions remain unclear, such as the patient populations who benefit most from APP, the best length of daily …
RECENT FINDINGS: Numerous clinical studies have been conducted to investigate the effects of APP on oxygenation, intubation, and mort …
22,674 results
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