PubMed

TRPC1 channels are critical for hypertrophic signaling in the heart.

Seth M, Zhang ZS, Mao L, Graham V, Burch J, Stiber J, Tsiokas L, Winn M, Abramowitz J, Rockman HA, Birnbaumer L, Rosenberg P.

Circ Res. 2009 Nov 6;105(10):1023-30. Epub 2009 Sep 24.PMID: 19797170 [PubMed - in process]Related articles

Function and regulation of TRPP2 at the plasma membrane.

Tsiokas L.

Am J Physiol Renal Physiol. 2009 Jul;297(1):F1-9. Epub 2009 Feb 25. Review.PMID: 19244406 [PubMed - indexed for MEDLINE]Related articles

Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2.

Felekkis KN, Koupepidou P, Kastanos E, Witzgall R, Bai CX, Li L, Tsiokas L, Gretz N, Deltas C.

BMC Nephrol. 2008 Aug 25;9:10.PMID: 18721488 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2.

Feng S, Okenka GM, Bai CX, Streets AJ, Newby LJ, DeChant BT, Tsiokas L, Obara T, Ong AC.

J Biol Chem. 2008 Oct 17;283(42):28471-9. Epub 2008 Aug 13.PMID: 18701462 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of TRPP2 through mDia1-dependent voltage gating.

Bai CX, Kim S, Li WP, Streets AJ, Ong AC, Tsiokas L.

EMBO J. 2008 May 7;27(9):1345-56. Epub 2008 Apr 3.PMID: 18388856 [PubMed - indexed for MEDLINE]Related articlesFree article

Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits.

Bai CX, Giamarchi A, Rodat-Despoix L, Padilla F, Downs T, Tsiokas L, Delmas P.

EMBO Rep. 2008 May;9(5):472-9. Epub 2008 Mar 7.PMID: 18323855 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of TRPC3 leads to disappearance of store-operated channels and formation of a new type of store-independent channels in A431 cells.

Kaznacheyeva E, Glushankova L, Bugaj V, Zimina O, Skopin A, Alexeenko V, Tsiokas L, Bezprozvanny I, Mozhayeva GN.

J Biol Chem. 2007 Aug 10;282(32):23655-62. Epub 2007 Jun 14.PMID: 17569672 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell biology of polycystin-2.

Tsiokas L, Kim S, Ong EC.

Cell Signal. 2007 Mar;19(3):444-53. Epub 2006 Nov 3. Review.PMID: 17084592 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-catenin regulates myogenesis by relieving I-mfa-mediated suppression of myogenic regulatory factors in P19 cells.

Pan W, Jia Y, Wang J, Tao D, Gan X, Tsiokas L, Jing N, Wu D, Li L.

Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17378-83. Epub 2005 Nov 21.PMID: 16301527 [PubMed - indexed for MEDLINE]Related articlesFree article

PKD2 functions as an epidermal growth factor-activated plasma membrane channel.

Ma R, Li WP, Rundle D, Kong J, Akbarali HI, Tsiokas L.

Mol Cell Biol. 2005 Sep;25(18):8285-98.PMID: 16135816 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of the retinal insulin receptor beta-subunit with the p85 subunit of phosphoinositide 3-kinase.

Rajala RV, McClellan ME, Chan MD, Tsiokas L, Anderson RE.

Biochemistry. 2004 May 18;43(19):5637-50.PMID: 15134438 [PubMed - indexed for MEDLINE]Related articles

PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles.

Rundle DR, Gorbsky G, Tsiokas L.

J Biol Chem. 2004 Jul 9;279(28):29728-39. Epub 2004 Apr 28.PMID: 15123714 [PubMed - indexed for MEDLINE]Related articlesFree article

Epidermal growth factor activates store-operated Ca2+ channels through an inositol 1,4,5-trisphosphate-independent pathway in human glomerular mesangial cells.

Li WP, Tsiokas L, Sansom SC, Ma R.

J Biol Chem. 2004 Feb 6;279(6):4570-7. Epub 2003 Nov 11.PMID: 14612458 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1.

Ma R, Rundle D, Jacks J, Koch M, Downs T, Tsiokas L.

J Biol Chem. 2003 Dec 26;278(52):52763-72. Epub 2003 Oct 6.PMID: 14530267 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific detection of the endogenous transient receptor potential (TRP)-1 protein in liver and airway smooth muscle cells using immunoprecipitation and Western-blot analysis.

Ong HL, Chen J, Chataway T, Brereton H, Zhang L, Downs T, Tsiokas L, Barritt G.

Biochem J. 2002 Jun 15;364(Pt 3):641-8.PMID: 12049627 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell surface glypicans are low-affinity endostatin receptors.

Karumanchi SA, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai JI, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen RL, Lander AD, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme VP.

Mol Cell. 2001 Apr;7(4):811-22.PMID: 11336704 [PubMed - indexed for MEDLINE]Related articles

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.

Hanaoka K, Qian F, Boletta A, Bhunia AK, Piontek K, Tsiokas L, Sukhatme VP, Guggino WB, Germino GG.

Nature. 2000 Dec 21-28;408(6815):990-4.PMID: 11140688 [PubMed - indexed for MEDLINE]Related articles

Interaction between RGS7 and polycystin.

Kim E, Arnould T, Sellin L, Benzing T, Comella N, Kocher O, Tsiokas L, Sukhatme VP, Walz G.

Proc Natl Acad Sci U S A. 1999 May 25;96(11):6371-6.PMID: 10339594 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2.

Arnould T, Sellin L, Benzing T, Tsiokas L, Cohen HT, Kim E, Walz G.

Mol Cell Biol. 1999 May;19(5):3423-34.PMID: 10207066 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific association of the gene product of PKD2 with the TRPC1 channel.

Tsiokas L, Arnould T, Zhu C, Kim E, Walz G, Sukhatme VP.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3934-9.PMID: 10097141 [PubMed - indexed for MEDLINE]Related articlesFree article