PubMed

Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.

Shtiegman K, Kochupurakkal BS, Zwang Y, Pines G, Starr A, Vexler A, Citri A, Katz M, Lavi S, Ben-Basat Y, Benjamin S, Corso S, Gan J, Yosef RB, Giordano S, Yarden Y.

Oncogene. 2007 Oct 25;26(49):6968-78. Epub 2007 May 7.PMID: 17486068 [PubMed - indexed for MEDLINE]Related articles

Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases.

Oved S, Mosesson Y, Zwang Y, Santonico E, Shtiegman K, Marmor MD, Kochupurakkal BS, Katz M, Lavi S, Cesareni G, Yarden Y.

J Biol Chem. 2006 Aug 4;281(31):21640-51. Epub 2006 May 30.PMID: 16735510 [PubMed - indexed for MEDLINE]Related articlesFree article

Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.

Amit I, Yakir L, Katz M, Zwang Y, Marmor MD, Citri A, Shtiegman K, Alroy I, Tuvia S, Reiss Y, Roubini E, Cohen M, Wides R, Bacharach E, Schubert U, Yarden Y.

Genes Dev. 2004 Jul 15;18(14):1737-52.PMID: 15256501 [PubMed - indexed for MEDLINE]Related articlesFree article

Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation.

Mosesson Y, Shtiegman K, Katz M, Zwang Y, Vereb G, Szollosi J, Yarden Y.

J Biol Chem. 2003 Jun 13;278(24):21323-6. Epub 2003 Apr 28.PMID: 12719435 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of ubiquitylation in signaling by growth factors: implications to cancer.

Shtiegman K, Yarden Y.

Semin Cancer Biol. 2003 Feb;13(1):29-40. Review.PMID: 12507554 [PubMed - indexed for MEDLINE]Related articles

Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.

Katz M, Shtiegman K, Tal-Or P, Yakir L, Mosesson Y, Harari D, Machluf Y, Asao H, Jovin T, Sugamura K, Yarden Y.

Traffic. 2002 Oct;3(10):740-51.PMID: 12230472 [PubMed - indexed for MEDLINE]Related articles

A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling.

Waterman H, Katz M, Rubin C, Shtiegman K, Lavi S, Elson A, Jovin T, Yarden Y.

EMBO J. 2002 Feb 1;21(3):303-13. Erratum in: EMBO J 2002 Jul 15;21(14):3917. PMID: 11823423 [PubMed - indexed for MEDLINE]Related articlesFree article

Voluntary ethanol consumption in male adolescent hamsters increases testosterone and aggression.

Ferris CF, Shtiegman K, King JA.

Physiol Behav. 1998 Mar;63(5):739-44.PMID: 9617993 [PubMed - indexed for MEDLINE]Related articles