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    Results: 1 to 20 of 72

    1.

    Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animals.

    Meinke PT, Colletti SL, Fisher MH, Wyvratt MJ, Shih TL, Ayer MB, Li C, Lim J, Ok D, Salva S, Warmke LM, Zakson M, Michael BF, Demontigny P, Ostlind DA, Fink D, Drag M, Schmatz DM, Shoop WL.

    J Med Chem. 2009 Jun 11;52(11):3505-15.PMID: 19445514 [PubMed - indexed for MEDLINE]Related articles

    2.

    Comparative disposition and metabolism of paraherquamide in sheep, gerbils, and dogs.

    Aloysius HA, Elipe MV, Arison BH, Faidley TD, Michael BF, Blizzard TA, Thompson DR, Shoop WL, Tschirret-Guth RA.

    Drug Metab Dispos. 2008 Aug;36(8):1659-69. Epub 2008 May 27.PMID: 18505789 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Isolation and insecticidal/anthelmintic activity of xanthonol, a novel bis-xanthone, from a non-sporulating fungal species.

    Ondeyka JG, Dombrowski AW, Polishook JP, Felcetto T, Shoop WL, Guan Z, Singh SB.

    J Antibiot (Tokyo). 2006 May;59(5):288-92.PMID: 16883778 [PubMed - indexed for MEDLINE]Related articles

    4.

    Platensimycin is a selective FabF inhibitor with potent antibiotic properties.

    Wang J, Soisson SM, Young K, Shoop W, Kodali S, Galgoci A, Painter R, Parthasarathy G, Tang YS, Cummings R, Ha S, Dorso K, Motyl M, Jayasuriya H, Ondeyka J, Herath K, Zhang C, Hernandez L, Allocco J, Basilio A, Tormo JR, Genilloud O, Vicente F, Pelaez F, Colwell L, Lee SH, Michael B, Felcetto T, Gill C, Silver LL, Hermes JD, Bartizal K, Barrett J, Schmatz D, Becker JW, Cully D, Singh SB.

    Nature. 2006 May 18;441(7091):358-61.PMID: 16710421 [PubMed - indexed for MEDLINE]Related articles

    5.

    Immunogenicity and protective efficacy of Bacillus anthracis poly-gamma-D-glutamic acid capsule covalently coupled to a protein carrier using a novel triazine-based conjugation strategy.

    Joyce J, Cook J, Chabot D, Hepler R, Shoop W, Xu Q, Stambaugh T, Aste-Amezaga M, Wang S, Indrawati L, Bruner M, Friedlander A, Keller P, Caulfield M.

    J Biol Chem. 2006 Feb 24;281(8):4831-43. Epub 2005 Nov 17.PMID: 16293624 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    p38 MAP kinase inhibitors: metabolically stabilized piperidine-substituted quinolinones and naphthyridinones.

    Bao J, Hunt JA, Miao S, Rupprecht KM, Stelmach JE, Liu L, Ruzek RD, Sinclair PJ, Pivnichny JV, Hop CE, Kumar S, Zaller DM, Shoop WL, O'neill EA, O'keefe SJ, Thompson CM, Cubbon RM, Wang R, Zhang WX, Thompson JE, Doherty JB.

    Bioorg Med Chem Lett. 2006 Jan 1;16(1):64-8. Epub 2005 Oct 18.PMID: 16242322 [PubMed - indexed for MEDLINE]Related articles

    7.

    Anthrax lethal factor inhibition.

    Shoop WL, Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny JV, Felcetto T, Michael BF, Bansal A, Cummings RT, Cunningham BR, Friedlander AM, Douglas CM, Patel SB, Wisniewski D, Scapin G, Salowe SP, Zaller DM, Chapman KT, Scolnick EM, Schmatz DM, Bartizal K, MacCoss M, Hermes JD.

    Proc Natl Acad Sci U S A. 2005 May 31;102(22):7958-63. Epub 2005 May 23.PMID: 15911756 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Nodulisporic acids D-F: structure, biological activities, and biogenetic relationships.

    Singh SB, Ondeyka JG, Jayasuriya H, Zink DL, Ha SN, Dahl-Roshak A, Greene J, Kim JA, Smith MM, Shoop W, Tkacz JS.

    J Nat Prod. 2004 Sep;67(9):1496-506.PMID: 15387649 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Rediocides B-E, potent insecticides from Trigonostemon reidioides.

    Jayasuriya H, Zink DL, Borris RP, Nanakorn W, Beck HT, Balick MJ, Goetz MA, Gregory L, Shoop WL, Singh SB.

    J Nat Prod. 2004 Feb;67(2):228-31.PMID: 14987064 [PubMed - indexed for MEDLINE]Related articles

    10.

    Isolation and insecticidal activity of mellamide from Aspergillus melleus.

    Ondeyka JG, Dombrowski AW, Polishook JP, Felcetto T, Shoop WL, Guan Z, Singh SB.

    J Ind Microbiol Biotechnol. 2003 Apr;30(4):220-4. Epub 2003 Apr 8.PMID: 12687496 [PubMed - indexed for MEDLINE]Related articles

    11.

    Nodulisporic acids C, C1, and C2: a series of D-ring-opened nodulisporic acids from the fungus Nodulisporium sp.

    Ondeyka JG, Byrne K, Vesey D, Zink DL, Shoop WL, Goetz MA, Singh SB.

    J Nat Prod. 2003 Jan;66(1):121-4.PMID: 12542359 [PubMed - indexed for MEDLINE]Related articles

    12.

    Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones.

    Colletti SL, Frie JL, Dixon EC, Singh SB, Choi BK, Scapin G, Fitzgerald CE, Kumar S, Nichols EA, O'Keefe SJ, O'Neill EA, Porter G, Samuel K, Schmatz DM, Schwartz CD, Shoop WL, Thompson CM, Thompson JE, Wang R, Woods A, Zaller DM, Doherty JB.

    J Med Chem. 2003 Jan 30;46(3):349-52.PMID: 12540232 [PubMed - indexed for MEDLINE]Related articles

    13.

    Amphidial structure of ivermectin-resistant and susceptible laboratory and field strains of Haemonchus contortus.

    Freeman AS, Nghiem C, Li J, Ashton FT, Guerrero J, Shoop WL, Schad GA.

    Vet Parasitol. 2003 Jan 2;110(3-4):217-26.PMID: 12482650 [PubMed - indexed for MEDLINE]Related articles

    14.

    Nodulisporic acid side-chain modifications: access to the 2", 3", 4", and 6" registers.

    Chakravarty PK, Shih TL, Colletti SL, Ayer MB, Snedden C, Kuo H, Tyagarajan S, Gregory L, Zakson-Aiken M, Shoop WL, Schmatz DM, Wyvratt M, Fisher MH, Meinke PT.

    Bioorg Med Chem Lett. 2003 Jan 6;13(1):147-50.PMID: 12467636 [PubMed - indexed for MEDLINE]Related articles

    15.

    Nodulisporic acid B, B1, and B2: a series of 1'-deoxy-nodulisporic acids from Nodulisporium sp.

    Ondeyka JG, Dahl-Roshak AM, Tkacz JS, Zink DL, Zakson-Aiken M, Shoop WL, Goetz MA, Singh SB.

    Bioorg Med Chem Lett. 2002 Oct 21;12(20):2941-4.PMID: 12270179 [PubMed - indexed for MEDLINE]Related articles

    16.

    Transmammary transmission of Strongyloides stercoralis in dogs.

    Shoop WL, Michael BF, Eary CH, Haines HW.

    J Parasitol. 2002 Jun;88(3):536-9.PMID: 12099422 [PubMed - indexed for MEDLINE]Related articles

    17.

    Side-chain homologation of nodulisporic acid: synthesis of potent new dienyl derivatives.

    Ok D, Li C, Shih TL, Salva S, Ayer MB, Colletti SL, Chakravarty PK, Wyvratt MJ, Fisher MH, Gregory L, Zakson-Aiken M, Shoop WL, Schmatz DM, Meinke PT.

    Bioorg Med Chem Lett. 2002 Jul 8;12(13):1751-4.PMID: 12067553 [PubMed - indexed for MEDLINE]Related articles

    18.

    Comparison of nodulisporic acid analogs in a Lucilia sericata in vitro assay and a Ctenocephalides felis membrane feeding system.

    Felcetto T, Ondeyka J, Colletti SL, Meinke PT, Shoop WL.

    J Parasitol. 2002 Apr;88(2):223-6.PMID: 12053989 [PubMed - indexed for MEDLINE]Related articles

    19.

    Nodulisporic acid: its chemistry and biology.

    Meinke PT, Smith MM, Shoop WL.

    Curr Top Med Chem. 2002 Jul;2(7):655-74. Review.PMID: 12052184 [PubMed - indexed for MEDLINE]Related articles

    20.

    Development of a mouse model to determine the systemic activity of potential flea-control compounds.

    Santora KA, Zakson-Aiken M, Rasa C, Shoop W.

    Vet Parasitol. 2002 Mar 20;104(3):257-64.PMID: 11812623 [PubMed - indexed for MEDLINE]Related articles

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