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    Results: 1 to 20 of 27

    1.

    BAK and BAX deletion using zinc-finger nucleases yields apoptosis-resistant CHO cells.

    Cost GJ, Freyvert Y, Vafiadis A, Santiago Y, Miller JC, Rebar E, Collingwood TN, Snowden A, Gregory PD.

    Biotechnol Bioeng. 2009 Sep 23. [Epub ahead of print]PMID: 19777580 [PubMed - as supplied by publisher]Related articles

    2.

    Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.

    Hockemeyer D, Soldner F, Beard C, Gao Q, Mitalipova M, DeKelver RC, Katibah GE, Amora R, Boydston EA, Zeitler B, Meng X, Miller JC, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R.

    Nat Biotechnol. 2009 Sep;27(9):851-7. Epub 2009 Aug 13.PMID: 19680244 [PubMed - in process]Related articles

    3.

    Knockout rats via embryo microinjection of zinc-finger nucleases.

    Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, Kalloway S, Weiler H, Ménoret S, Anegon I, Davis GD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jacob HJ, Buelow R.

    Science. 2009 Jul 24;325(5939):433.PMID: 19628861 [PubMed - indexed for MEDLINE]Related articles

    4.

    Precise genome modification in the crop species Zea mays using zinc-finger nucleases.

    Shukla VK, Doyon Y, Miller JC, DeKelver RC, Moehle EA, Worden SE, Mitchell JC, Arnold NL, Gopalan S, Meng X, Choi VM, Rock JM, Wu YY, Katibah GE, Zhifang G, McCaskill D, Simpson MA, Blakeslee B, Greenwalt SA, Butler HJ, Hinkley SJ, Zhang L, Rebar EJ, Gregory PD, Urnov FD.

    Nature. 2009 May 21;459(7245):437-41. Epub 2009 Apr 29.PMID: 19404259 [PubMed - indexed for MEDLINE]Related articles

    5.

    Targeted transgene integration in plant cells using designed zinc finger nucleases.

    Cai CQ, Doyon Y, Ainley WM, Miller JC, Dekelver RC, Moehle EA, Rock JM, Lee YL, Garrison R, Schulenberg L, Blue R, Worden A, Baker L, Faraji F, Zhang L, Holmes MC, Rebar EJ, Collingwood TN, Rubin-Wilson B, Gregory PD, Urnov FD, Petolino JF.

    Plant Mol Biol. 2009 Apr;69(6):699-709. Epub 2008 Dec 27.PMID: 19112554 [PubMed - indexed for MEDLINE]Related articles

    6.

    Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases.

    Perez EE, Wang J, Miller JC, Jouvenot Y, Kim KA, Liu O, Wang N, Lee G, Bartsevich VV, Lee YL, Guschin DY, Rupniewski I, Waite AJ, Carpenito C, Carroll RG, Orange JS, Urnov FD, Rebar EJ, Ando D, Gregory PD, Riley JL, Holmes MC, June CH.

    Nat Biotechnol. 2008 Jul;26(7):808-16. Epub 2008 Jun 29.PMID: 18587387 [PubMed - indexed for MEDLINE]Related articles

    7.

    Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases.

    Doyon Y, McCammon JM, Miller JC, Faraji F, Ngo C, Katibah GE, Amora R, Hocking TD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Amacher SL.

    Nat Biotechnol. 2008 Jun;26(6):702-8. Epub 2008 May 25.PMID: 18500334 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

    Santiago Y, Chan E, Liu PQ, Orlando S, Zhang L, Urnov FD, Holmes MC, Guschin D, Waite A, Miller JC, Rebar EJ, Gregory PD, Klug A, Collingwood TN.

    Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5809-14. Epub 2008 Mar 21.PMID: 18359850 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    An improved zinc-finger nuclease architecture for highly specific genome editing.

    Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA, Gregory PD, Pabo CO, Rebar EJ.

    Nat Biotechnol. 2007 Jul;25(7):778-85. Epub 2007 Jul 1.PMID: 17603475 [PubMed - indexed for MEDLINE]Related articles

    10.

    Enhanced protein production by engineered zinc finger proteins.

    Reik A, Zhou Y, Collingwood TN, Warfe L, Bartsevich V, Kong Y, Henning KA, Fallentine BK, Zhang L, Zhong X, Jouvenot Y, Jamieson AC, Rebar EJ, Case CC, Korman A, Li XY, Black A, King DJ, Gregory PD.

    Biotechnol Bioeng. 2007 Aug 1;97(5):1180-9.PMID: 17171718 [PubMed - indexed for MEDLINE]Related articles

    11.

    Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy.

    Price SA, Dent C, Duran-Jimenez B, Liang Y, Zhang L, Rebar EJ, Case CC, Gregory PD, Martin TJ, Spratt SK, Tomlinson DR.

    Diabetes. 2006 Jun;55(6):1847-54.PMID: 16731852 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice.

    Yu J, Lei L, Liang Y, Hinh L, Hickey RP, Huang Y, Liu D, Yeh JL, Rebar E, Case C, Spratt K, Sessa WC, Giordano FJ.

    FASEB J. 2006 Mar;20(3):479-81. Epub 2006 Jan 19.PMID: 16423874 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Gene regulation in planta by plant-derived engineered zinc finger protein transcription factors.

    Holmes-Davis R, Li G, Jamieson AC, Rebar EJ, Liu Q, Kong Y, Case CC, Gregory PD.

    Plant Mol Biol. 2005 Feb;57(3):411-23.PMID: 15830130 [PubMed - indexed for MEDLINE]Related articles

    14.

    Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia.

    Dai Q, Huang J, Klitzman B, Dong C, Goldschmidt-Clermont PJ, March KL, Rokovich J, Johnstone B, Rebar EJ, Spratt SK, Case CC, Kontos CD, Annex BH.

    Circulation. 2004 Oct 19;110(16):2467-75. Epub 2004 Oct 11.PMID: 15477407 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Development of pro-angiogenic engineered transcription factors for the treatment of cardiovascular disease.

    Rebar EJ.

    Expert Opin Investig Drugs. 2004 Jul;13(7):829-39. Review.PMID: 15212621 [PubMed - indexed for MEDLINE]Related articles

    16.

    Elevation of seed alpha-tocopherol levels using plant-based transcription factors targeted to an endogenous locus.

    Van Eenennaam AL, Li G, Venkatramesh M, Levering C, Gong X, Jamieson AC, Rebar EJ, Shewmaker CK, Case CC.

    Metab Eng. 2004 Apr;6(2):101-8.PMID: 15113563 [PubMed - indexed for MEDLINE]Related articles

    17.

    Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors.

    Snowden AW, Zhang L, Urnov F, Dent C, Jouvenot Y, Zhong X, Rebar EJ, Jamieson AC, Zhang HS, Tan S, Case CC, Pabo CO, Wolffe AP, Gregory PD.

    Cancer Res. 2003 Dec 15;63(24):8968-76.PMID: 14695215 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Novel approaches to controlling transcription.

    Schaal TD, Holmes MC, Rebar EJ, Case CC.

    Genet Eng (N Y). 2002;24:137-78. Review. No abstract available. PMID: 12416304 [PubMed - indexed for MEDLINE]Related articles

    19.

    Induction of angiogenesis in a mouse model using engineered transcription factors.

    Rebar EJ, Huang Y, Hickey R, Nath AK, Meoli D, Nath S, Chen B, Xu L, Liang Y, Jamieson AC, Zhang L, Spratt SK, Case CC, Wolffe A, Giordano FJ.

    Nat Med. 2002 Dec;8(12):1427-32. Epub 2002 Nov 4.PMID: 12415262 [PubMed - indexed for MEDLINE]Related articles

    20.

    Designed transcription factors as tools for therapeutics and functional genomics.

    Urnov FD, Rebar EJ.

    Biochem Pharmacol. 2002 Sep;64(5-6):919-23. Review.PMID: 12213587 [PubMed - indexed for MEDLINE]Related articles

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