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    Results: 13

    1.

    The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization.

    Clausen RP, Naur P, Kristensen AS, Greenwood JR, Strange M, Bräuner-Osborne H, Jensen AA, Nielsen AS, Geneser U, Ringgaard LM, Nielsen B, Pickering DS, Brehm L, Gajhede M, Krogsgaard-Larsen P, Kastrup JS.

    J Med Chem. 2009 Aug 13;52(15):4911-22.PMID: 19588945 [PubMed - indexed for MEDLINE]Related articles

    2.

    Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.

    Frydenvang K, Lash LL, Naur P, Postila PA, Pickering DS, Smith CM, Gajhede M, Sasaki M, Sakai R, Pentikaïnen OT, Swanson GT, Kastrup JS.

    J Biol Chem. 2009 May 22;284(21):14219-29. Epub 2009 Mar 18.PMID: 19297335 [PubMed - indexed for MEDLINE]Related articles

    3.

    Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium.

    Hansen KB, Naur P, Kurtkaya NL, Kristensen AS, Gajhede M, Kastrup JS, Traynelis SF.

    J Neurosci. 2009 Jan 28;29(4):907-17.PMID: 19176800 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4.

    Kasper C, Frydenvang K, Naur P, Gajhede M, Pickering DS, Kastrup JS.

    FEBS Lett. 2008 Dec 10;582(29):4089-94. Epub 2008 Nov 18.PMID: 19022251 [PubMed - indexed for MEDLINE]Related articles

    5.

    Ionotropic glutamate-like receptor delta2 binds D-serine and glycine.

    Naur P, Hansen KB, Kristensen AS, Dravid SM, Pickering DS, Olsen L, Vestergaard B, Egebjerg J, Gajhede M, Traynelis SF, Kastrup JS.

    Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14116-21. Epub 2007 Aug 21.PMID: 17715062 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.

    Hald H, Naur P, Pickering DS, Sprogøe D, Madsen U, Timmermann DB, Ahring PK, Liljefors T, Schousboe A, Egebjerg J, Gajhede M, Kastrup JS.

    J Biol Chem. 2007 Aug 31;282(35):25726-36. Epub 2007 Jun 20.PMID: 17581823 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.

    Holm MM, Naur P, Vestergaard B, Geballe MT, Gajhede M, Kastrup JS, Traynelis SF, Egebjerg J.

    J Biol Chem. 2005 Oct 21;280(42):35469-76. Epub 2005 Aug 15.PMID: 16103115 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate.

    Naur P, Vestergaard B, Skov LK, Egebjerg J, Gajhede M, Kastrup JS.

    FEBS Lett. 2005 Feb 14;579(5):1154-60.PMID: 15710405 [PubMed - indexed for MEDLINE]Related articles

    9.

    Arabidopsis mutants in the C-S lyase of glucosinolate biosynthesis establish a critical role for indole-3-acetaldoxime in auxin homeostasis.

    Mikkelsen MD, Naur P, Halkier BA.

    Plant J. 2004 Mar;37(5):770-7.PMID: 14871316 [PubMed - indexed for MEDLINE]Related articles

    10.

    CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis.

    Naur P, Petersen BL, Mikkelsen MD, Bak S, Rasmussen H, Olsen CE, Halkier BA.

    Plant Physiol. 2003 Sep;133(1):63-72.PMID: 12970475 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.

    Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA.

    Plant J. 2003 Mar;33(5):923-37.PMID: 12609033 [PubMed - indexed for MEDLINE]Related articles

    12.

    CYP79B1 from Sinapis alba converts tryptophan to indole-3-acetaldoxime.

    Naur P, Hansen CH, Bak S, Hansen BG, Jensen NB, Nielsen HL, Halkier BA.

    Arch Biochem Biophys. 2003 Jan 1;409(1):235-41.PMID: 12464264 [PubMed - indexed for MEDLINE]Related articles

    13.

    CYP83b1 is the oxime-metabolizing enzyme in the glucosinolate pathway in Arabidopsis.

    Hansen CH, Du L, Naur P, Olsen CE, Axelsen KB, Hick AJ, Pickett JA, Halkier BA.

    J Biol Chem. 2001 Jul 6;276(27):24790-6. Epub 2001 May 1.PMID: 11333274 [PubMed - indexed for MEDLINE]Related articles

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