PubMed

Detection of retroviral integration sites by linear amplification-mediated PCR and tracking of individual integration clones in different samples.

Schmidt M, Schwarzwaelder K, Bartholomae CC, Glimm H, von Kalle C.

Methods Mol Biol. 2009;506:363-72.PMID: 19110638 [PubMed - indexed for MEDLINE]Related articles

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients.

Howe SJ, Mansour MR, Schwarzwaelder K, Bartholomae C, Hubank M, Kempski H, Brugman MH, Pike-Overzet K, Chatters SJ, de Ridder D, Gilmour KC, Adams S, Thornhill SI, Parsley KL, Staal FJ, Gale RE, Linch DC, Bayford J, Brown L, Quaye M, Kinnon C, Ancliff P, Webb DK, Schmidt M, von Kalle C, Gaspar HB, Thrasher AJ.

J Clin Invest. 2008 Sep;118(9):3143-50.PMID: 18688286 [PubMed - indexed for MEDLINE]Related articlesFree article

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

Schmidt M, Schwarzwaelder K, Bartholomae C, Zaoui K, Ball C, Pilz I, Braun S, Glimm H, von Kalle C.

Nat Methods. 2007 Dec;4(12):1051-7.PMID: 18049469 [PubMed - indexed for MEDLINE]Related articles

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo.

Schwarzwaelder K, Howe SJ, Schmidt M, Brugman MH, Deichmann A, Glimm H, Schmidt S, Prinz C, Wissler M, King DJ, Zhang F, Parsley KL, Gilmour KC, Sinclair J, Bayford J, Peraj R, Pike-Overzet K, Staal FJ, de Ridder D, Kinnon C, Abel U, Wagemaker G, Gaspar HB, Thrasher AJ, von Kalle C.

J Clin Invest. 2007 Aug;117(8):2241-9.PMID: 17671654 [PubMed - indexed for MEDLINE]Related articlesFree article

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy.

Deichmann A, Hacein-Bey-Abina S, Schmidt M, Garrigue A, Brugman MH, Hu J, Glimm H, Gyapay G, Prum B, Fraser CC, Fischer N, Schwarzwaelder K, Siegler ML, de Ridder D, Pike-Overzet K, Howe SJ, Thrasher AJ, Wagemaker G, Abel U, Staal FJ, Delabesse E, Villeval JL, Aronow B, Hue C, Prinz C, Wissler M, Klanke C, Weissenbach J, Alexander I, Fischer A, von Kalle C, Cavazzana-Calvo M.

J Clin Invest. 2007 Aug;117(8):2225-32.PMID: 17671652 [PubMed - indexed for MEDLINE]Related articlesFree article

Real-time definition of non-randomness in the distribution of genomic events.

Abel U, Deichmann A, Bartholomae C, Schwarzwaelder K, Glimm H, Howe S, Thrasher A, Garrigue A, Hacein-Bey-Abina S, Cavazzana-Calvo M, Fischer A, Jaeger D, von Kalle C, Schmidt M.

PLoS One. 2007 Jun 27;2(6):e570.PMID: 17593969 [PubMed]Related articlesFree article

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

Ott MG, Schmidt M, Schwarzwaelder K, Stein S, Siler U, Koehl U, Glimm H, Kühlcke K, Schilz A, Kunkel H, Naundorf S, Brinkmann A, Deichmann A, Fischer M, Ball C, Pilz I, Dunbar C, Du Y, Jenkins NA, Copeland NG, Lüthi U, Hassan M, Thrasher AJ, Hoelzer D, von Kalle C, Seger R, Grez M.

Nat Med. 2006 Apr;12(4):401-9. Epub 2006 Apr 2.PMID: 16582916 [PubMed - indexed for MEDLINE]Related articles

Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients.

Glimm H, Schmidt M, Fischer M, Schwarzwaelder K, Wissler M, Klingenberg S, Prinz C, Waller CF, Lange W, Eaves CJ, von Kalle C.

Blood. 2005 Aug 1;106(3):893-8. Epub 2005 Apr 21.PMID: 15845903 [PubMed - indexed for MEDLINE]Related articlesFree article