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Year Number of Results
2019 13
2020 15
2021 15
2022 12
2023 10
2024 3

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2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
Lavonas EJ, Akpunonu PD, Arens AM, Babu KM, Cao D, Hoffman RS, Hoyte CO, Mazer-Amirshahi ME, Stolbach A, St-Onge M, Thompson TM, Wang GS, Hoover AV, Drennan IR; American Heart Association. Lavonas EJ, et al. Circulation. 2023 Oct 17;148(16):e149-e184. doi: 10.1161/CIR.0000000000001161. Epub 2023 Sep 18. Circulation. 2023. PMID: 37721023 Free article. Review.
Based on structured evidence reviews, guidelines are provided for the treatment of critical poisoning from benzodiazepines, beta-adrenergic receptor antagonists (also known as beta-blockers), L-type calcium channel antagonists (commonly c …
Based on structured evidence reviews, guidelines are provided for the treatment of critical poisoning from benzodiazepines, beta-a
Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial.
Forlenza GP, McVean J, Beck RW, Bauza C, Bailey R, Buckingham B, DiMeglio LA, Sherr JL, Clements M, Neyman A, Evans-Molina C, Sims EK, Messer LH, Ekhlaspour L, McDonough R, Van Name M, Rojas D, Beasley S, DuBose S, Kollman C, Moran A; CLVer Study Group. Forlenza GP, et al. JAMA. 2023 Mar 28;329(12):990-999. doi: 10.1001/jama.2023.2064. JAMA. 2023. PMID: 36826844 Free PMC article.
IMPORTANCE: In preclinical studies, thioredoxin-interacting protein overexpression induces pancreatic beta cell apoptosis and is involved in glucotoxicity-induced beta cell death. Calcium channel blockers reduce these effects and may be benefici …
IMPORTANCE: In preclinical studies, thioredoxin-interacting protein overexpression induces pancreatic beta cell apoptosis and is invo …
Cardiotoxic Medication Poisoning.
Cole JB, Arens AM. Cole JB, et al. Emerg Med Clin North Am. 2022 May;40(2):395-416. doi: 10.1016/j.emc.2022.01.014. Epub 2022 Apr 5. Emerg Med Clin North Am. 2022. PMID: 35461630 Review.
Beta-blockers and calcium channel blockers result in a disproportionate number of fatalities from cardiac medication overdoses, and share similar characteristics. High-dose insulin is a superior therapy for both overdoses, but is likely s
Beta-blockers and calcium channel blockers result in a disproportionate number of fatalities from cardiac
HIGH-DOSE INSULIN EUGLYCEMIC THERAPY.
Hamzić J, Raos D, Radulović B. Hamzić J, et al. Acta Clin Croat. 2022 Jun;61(Suppl 1):73-77. doi: 10.20471/acc.2022.61.s1.12. Acta Clin Croat. 2022. PMID: 36304811 Free PMC article. Review.
Calcium channel blockers and beta-blockers toxicity/poisoning are one of the most common causes of poisoning. ...In this paper, we will review the mechanism for this type of treatment, propose a potential protocol for its application and address
Calcium channel blockers and beta-blockers toxicity/poisoning are one of the most common causes of poison
Diabetogenic effects of cardioprotective drugs.
Bell DSH, Goncalves E. Bell DSH, et al. Diabetes Obes Metab. 2021 Apr;23(4):877-885. doi: 10.1111/dom.14295. Epub 2021 Jan 5. Diabetes Obes Metab. 2021. PMID: 33319474 Review.
Drugs that protect against cardiovascular events in the patient with diabetes may also positively or negatively affect glycaemic control in the patient with established diabetes and may induce the development of diabetes in the predisposed patient. Mainly through increasing in
Drugs that protect against cardiovascular events in the patient with diabetes may also positively or negatively affect glycaemic control in …
Evaluation of high-dose insulin/euglycemia therapy for suspected beta-blocker or calcium channel blocker overdose following guideline implementation.
Schult RF, Nacca N, Grannell TL, Jorgensen RM, Acquisto NM. Schult RF, et al. Am J Health Syst Pharm. 2022 Mar 21;79(7):547-555. doi: 10.1093/ajhp/zxab439. Am J Health Syst Pharm. 2022. PMID: 34957477
PURPOSE: High-dose insulin/euglycemia (HDIE) is targeted therapy for beta-blocker and calcium channel blocker overdose. ...CONCLUSION: Hypoglycemia was reduced using an HDIE guideline and concentrated insulin....
PURPOSE: High-dose insulin/euglycemia (HDIE) is targeted therapy for beta-blocker and calcium channel blocker ov …
The association of calcium channel blockers with beta-cell function in type 2 diabetic patients: A cross-sectional study.
Zhao D, Cao Y, Yu CG, Yuan SS, Zhang N, Zhang YY, Staessen JA, Feng YM. Zhao D, et al. J Clin Hypertens (Greenwich). 2019 May;21(5):638-647. doi: 10.1111/jch.13517. Epub 2019 Mar 22. J Clin Hypertens (Greenwich). 2019. PMID: 30900372 Free PMC article.
Homa-beta was computed by Homeostasis Model Assessment model to evaluate beta-cell function using fasting C-peptide and glucose levels in the plasma. ...Multivariate-adjusted analysis demonstrated that use of calcium channel blockers (CCBs) was …
Homa-beta was computed by Homeostasis Model Assessment model to evaluate beta-cell function using fasting C-peptide and glucos …
Lowering and Raising Serum Urate Levels: Off-Label Effects of Commonly Used Medications.
Leung N, Yip K, Pillinger MH, Toprover M. Leung N, et al. Mayo Clin Proc. 2022 Jul;97(7):1345-1362. doi: 10.1016/j.mayocp.2022.02.027. Mayo Clin Proc. 2022. PMID: 35787862 Free PMC article. Review.
Potentially urate-lowering drugs include angiotensin II receptor blockers, calcium channel blockers, high-dose aspirin and salicylates, some nonsalicylate nonsteroidal anti-inflammatory drugs, angiotensin-converting enzyme inhibitors, sodium-glucose co …
Potentially urate-lowering drugs include angiotensin II receptor blockers, calcium channel blockers, high-dose a …
TXNIP inhibition in the treatment of diabetes. Verapamil as a novel therapeutic modality in diabetic patients.
Borowiec AM, Właszczuk A, Olakowska E, Lewin-Kowalik J. Borowiec AM, et al. Med Pharm Rep. 2022 Jul;95(3):243-250. doi: 10.15386/mpr-2187. Epub 2022 Jul 26. Med Pharm Rep. 2022. PMID: 36060506 Free PMC article. Review.
It activates NLRP3 inflamasomme and IL-1beta, a cytokine involved in type 2 diabetes and insulin resistance. TXNIP influences peroxisome proliferator-activated receptor alpha transcriptional activity, expression of glucose transporter-1, nitric oxide production in endothel …
It activates NLRP3 inflamasomme and IL-1beta, a cytokine involved in type 2 diabetes and insulin resistance. TXNIP influences peroxis …
Management of Calcium Channel Blocker Toxicity in the Pediatric Patient.
Bartlett JW, Walker PL. Bartlett JW, et al. J Pediatr Pharmacol Ther. 2019 Sep-Oct;24(5):378-389. doi: 10.5863/1551-6776-24.5.378. J Pediatr Pharmacol Ther. 2019. PMID: 31598101 Free PMC article. Review.
Calcium channel blockers (CCBs) are commonly prescribed cardiovascular medications used in several disease states including hypertension, coronary artery disease, and atrial fibrillation. ...Traditional first-line IV therapies include small boluses of fluids,
Calcium channel blockers (CCBs) are commonly prescribed cardiovascular medications used in several disease states inclu
60 results