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Hypercalcemia: A Review.
Walker MD, Shane E. Walker MD, et al. JAMA. 2022 Oct 25;328(16):1624-1636. doi: 10.1001/jama.2022.18331. JAMA. 2022. PMID: 36282253 Review.
OBSERVATIONS: Approximately 90% of people with hypercalcemia have primary hyperparathyroidism (PHPT) or malignancy. ...Asymptomatic hypercalcemia due to primary hyperparathyroidism is managed with parathyroidectomy or observation with monitoring, while …
OBSERVATIONS: Approximately 90% of people with hypercalcemia have primary hyperparathyroidism (PHPT) or malignancy. ...Asympto …
Drug-Related Hypercalcemia.
Lecoq AL, Livrozet M, Blanchard A, Kamenický P. Lecoq AL, et al. Endocrinol Metab Clin North Am. 2021 Dec;50(4):743-752. doi: 10.1016/j.ecl.2021.08.001. Endocrinol Metab Clin North Am. 2021. PMID: 34774245 Review.
Thiazide-induced hypercalcemia is mainly explained by enhanced renal proximal calcium reabsorption, changing preexistent asymptomatic normocalcemic or intermittently hypercalcemic hyperparathyroidism into the classic hypercalcemic hyperparathyroidism. Lithium …
Thiazide-induced hypercalcemia is mainly explained by enhanced renal proximal calcium reabsorption, changing preexistent asymptomatic …
Lithium-associated hyperparathyroidism.
Mifsud S, Cilia K, Mifsud EL, Gruppetta M. Mifsud S, et al. Br J Hosp Med (Lond). 2020 Nov 2;81(11):1-9. doi: 10.12968/hmed.2020.0457. Epub 2020 Nov 17. Br J Hosp Med (Lond). 2020. PMID: 33263481 Review.
Treatment with lithium can give rise to various endocrine and metabolic abnormalities, including thyroid dysfunction, nephrogenic diabetes insipidus and hypercalcaemia. Lithium may induce hypercalcaemia through both acute and chronic effects. ...The latter biochemic …
Treatment with lithium can give rise to various endocrine and metabolic abnormalities, including thyroid dysfunction, nephrogenic diabetes i …
Primary hyperparathyroidism.
Kowalski GJ, Buła G, Żądło D, Gawrychowska A, Gawrychowski J. Kowalski GJ, et al. Endokrynol Pol. 2020;71(3):260-270. doi: 10.5603/EP.a2020.0028. Endokrynol Pol. 2020. PMID: 32797471 Free article. Review.
It results in hypercalcaemia, which has a significant impact mainly on the kidneys and bones and results in a variety of signs and symptoms. Primary hyperparathyroidism should be treated because, if left without any therapy, it can lead even to death. ...
It results in hypercalcaemia, which has a significant impact mainly on the kidneys and bones and results in a variety of signs and sy …
Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism.
Minisola S, Arnold A, Belaya Z, Brandi ML, Clarke BL, Hannan FM, Hofbauer LC, Insogna KL, Lacroix A, Liberman U, Palermo A, Pepe J, Rizzoli R, Wermers R, Thakker RV. Minisola S, et al. J Bone Miner Res. 2022 Nov;37(11):2315-2329. doi: 10.1002/jbmr.4665. Epub 2022 Oct 17. J Bone Miner Res. 2022. PMID: 36245271 Free PMC article. Review.
In this narrative review, we present data gathered over four decades (1980-2020) on the epidemiology, pathophysiology and genetics of primary hyperparathyroidism (PHPT). PHPT is typically a disease of postmenopausal women, but its prevalence and incidence vary globally and …
In this narrative review, we present data gathered over four decades (1980-2020) on the epidemiology, pathophysiology and genetics of primar …
Medical management of primary hyperparathyroidism.
Bandeira F, de Moura Nóbrega J, de Oliveira LB, Bilezikian J. Bandeira F, et al. Arch Endocrinol Metab. 2022 Nov 11;66(5):689-693. doi: 10.20945/2359-3997000000558. Arch Endocrinol Metab. 2022. PMID: 36382758 Free PMC article. Review.
Primary hyperparathyroidism (PHPT) is an endocrine disorder resulting from the hyperfunction of one or more parathyroid glands, with hypersecretion of parathyroid hormone (PTH). ...
Primary hyperparathyroidism (PHPT) is an endocrine disorder resulting from the hyperfunction of one or more parathyroid glands, with …
Rare Causes of Hypercalcemia: 2021 Update.
Motlaghzadeh Y, Bilezikian JP, Sellmeyer DE. Motlaghzadeh Y, et al. J Clin Endocrinol Metab. 2021 Oct 21;106(11):3113-3128. doi: 10.1210/clinem/dgab504. J Clin Endocrinol Metab. 2021. PMID: 34240162 Review.
CONTEXT: Primary hyperparathyroidism and malignancy are the etiologies in 90% of cases of hypercalcemia. When these entities are not the etiology of hypercalcemia, uncommon conditions need to be considered. In 2005, Jacobs and Bilezikian published a clinical …
CONTEXT: Primary hyperparathyroidism and malignancy are the etiologies in 90% of cases of hypercalcemia. When these entities a …
Hypercalcemia in Pregnancy.
Dandurand K, Ali DS, Khan AA. Dandurand K, et al. Endocrinol Metab Clin North Am. 2021 Dec;50(4):753-768. doi: 10.1016/j.ecl.2021.07.009. Endocrinol Metab Clin North Am. 2021. PMID: 34774246 Review.
Hypercalcemic disorders are rare in pregnant women and are usually due to primary hyperparathyroidism. Clinical manifestations of hypercalcemia are nonspecific and can be masked by the physiologic changes of pregnancy. ...Conservative measures are appropriate in the …
Hypercalcemic disorders are rare in pregnant women and are usually due to primary hyperparathyroidism. Clinical manifestations of …
A Review of Current Clinical Concepts in the Pathophysiology, Etiology, Diagnosis, and Management of Hypercalcemia.
Tonon CR, Silva TAAL, Pereira FWL, Queiroz DAR, Junior ELF, Martins D, Azevedo PS, Okoshi MP, Zornoff LAM, de Paiva SAR, Minicucci MF, Polegato BF. Tonon CR, et al. Med Sci Monit. 2022 Feb 26;28:e935821. doi: 10.12659/MSM.935821. Med Sci Monit. 2022. PMID: 35217631 Free PMC article. Review.
Most cases are caused by primary hyperparathyroidism and malignancies. Various mechanisms are involved in the pathophysiology of hypercalcemia, such as excessive PTH production, production of parathyroid hormone-related protein (PTHrp), bone metastasis, extrarenal a …
Most cases are caused by primary hyperparathyroidism and malignancies. Various mechanisms are involved in the pathophysiology of h
1,023 results