PubMed

Prokineticin-1 evokes secretory and contractile activity in rat small intestine.

Wade PR, Palmer JM, Mabus J, Saunders PR, Prouty S, Chevalier K, Gareau MG, McKenney S, Hornby PJ.

Neurogastroenterol Motil. 2009 Nov 25. [Epub ahead of print]PMID: 19930539 [PubMed - as supplied by publisher]

TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation.

Cooper PR, Lamb R, Day ND, Branigan PJ, Kajekar R, San Mateo L, Hornby PJ, Panettieri RA Jr.

Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L530-7. Epub 2009 Jun 19.PMID: 19542247 [PubMed - indexed for MEDLINE]Related articles

Design and optimization of aniline-substituted tetrahydroquinoline C5a receptor antagonists.

Gong Y, Barbay JK, Buntinx M, Li J, Wauwe JV, Claes C, Lommen GV, Hornby PJ, He W.

Bioorg Med Chem Lett. 2008 Jul 15;18(14):3852-5. Epub 2008 Jun 20.PMID: 18595693 [PubMed - indexed for MEDLINE]Related articles

Synthesis and characterization of 5,6,7,8-tetrahydroquinoline C5a receptor antagonists.

Barbay JK, Gong Y, Buntinx M, Li J, Claes C, Hornby PJ, Van Lommen G, Van Wauwe J, He W.

Bioorg Med Chem Lett. 2008 Apr 15;18(8):2544-8. Epub 2008 Mar 20.PMID: 18378452 [PubMed - indexed for MEDLINE]Related articles

Synthesis and SAR of pyridazinone-substituted phenylalanine amide alpha4 integrin antagonists.

Gong Y, Kent Barbay J, Kimball ES, Santulli RJ, Carolyn Fisher M, Dyatkin AB, Miskowski TA, Hornby PJ, He W.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1331-5. Epub 2008 Jan 11.PMID: 18226905 [PubMed - indexed for MEDLINE]Related articles

Stimulation of neuronal receptors, neuropeptides and cytokines during experimental oil of mustard colitis.

Kimball ES, Prouty SP, Pavlick KP, Wallace NH, Schneider CR, Hornby PJ.

Neurogastroenterol Motil. 2007 May;19(5):390-400.PMID: 17509021 [PubMed - indexed for MEDLINE]Related articles

Functional effects and characteristics of cecum-projecting neurons in the dorsal motor nucleus of the vagus of rats.

Cao X, Ball AJ, Partosoedarso ER, Burmeister MA, Hornby PJ.

Auton Neurosci. 2007 Jan 30;131(1-2):1-8. Epub 2006 Sep 6.PMID: 16950660 [PubMed - indexed for MEDLINE]Related articles

Synthesis and biological evaluation of novel pyridazinone-based alpha4 integrin receptor antagonists.

Gong Y, Barbay JK, Dyatkin AB, Miskowski TA, Kimball ES, Prouty SM, Fisher MC, Santulli RJ, Schneider CR, Wallace NH, Ballentine SA, Hageman WE, Masucci JA, Maryanoff BE, Damiano BP, Andrade-Gordon P, Hlasta DJ, Hornby PJ, He W.

J Med Chem. 2006 Jun 1;49(11):3402-11.PMID: 16722660 [PubMed - indexed for MEDLINE]Related articles

Designing Spiegelmers to antagonise ghrelin.

Hornby PJ.

Gut. 2006 Jun;55(6):754-5. No abstract available. PMID: 16698747 [PubMed - indexed for MEDLINE]Related articlesFree article

Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium.

Kimball ES, Schneider CR, Wallace NH, Hornby PJ.

Am J Physiol Gastrointest Liver Physiol. 2006 Aug;291(2):G364-71. Epub 2006 Mar 30.PMID: 16574988 [PubMed - indexed for MEDLINE]Related articlesFree article

Aza-bicyclic amino acid carboxamides as alpha4beta1/alpha4beta7 integrin receptor antagonists.

Dyatkin AB, Gong Y, Miskowski TA, Kimball ES, Prouty SM, Fisher MC, Santulli RJ, Schneider CR, Wallace NH, Hornby PJ, Diamond C, Kinney WA, Maryanoff BE, Damiano BP, He W.

Bioorg Med Chem. 2005 Dec 15;13(24):6693-702. Epub 2005 Aug 19.PMID: 16112583 [PubMed - indexed for MEDLINE]Related articles

Age-related neurodegenerative changes and how they affect the gut.

Wade PR, Hornby PJ.

Sci Aging Knowledge Environ. 2005 Mar 23;2005(12):pe8. Review.PMID: 15788792 [PubMed - indexed for MEDLINE]Related articles

Acute colitis induction by oil of mustard results in later development of an IBS-like accelerated upper GI transit in mice.

Kimball ES, Palmer JM, D'Andrea MR, Hornby PJ, Wade PR.

Am J Physiol Gastrointest Liver Physiol. 2005 Jun;288(6):G1266-73. Epub 2005 Feb 3.PMID: 15691868 [PubMed - indexed for MEDLINE]Related articlesFree article

Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice.

Kimball ES, Wallace NH, Schneider CR, D'Andrea MR, Hornby PJ.

Neurogastroenterol Motil. 2004 Dec;16(6):811-8.PMID: 15601431 [PubMed - indexed for MEDLINE]Related articles

Involvement of cannabinoid receptors in gut motility and visceral perception.

Hornby PJ, Prouty SM.

Br J Pharmacol. 2004 Apr;141(8):1335-45. Review.PMID: 15100166 [PubMed - indexed for MEDLINE]Related articlesFree article

Central vagal stimulation evokes gastric volume changes in mice: a novel technique using a miniaturized barostat.

Monroe MJ, Hornby PJ, Partosoedarso ER.

Neurogastroenterol Motil. 2004 Feb;16(1):5-11.PMID: 14764200 [PubMed - indexed for MEDLINE]Related articles

Aza-bicyclic amino acid sulfonamides as alpha(4)beta(1)/alpha(4)beta(7) integrin antagonists.

Dyatkin AB, Hoekstra WJ, Kinney WA, Kontoyianni M, Santulli RJ, Kimball ES, Fisher MC, Prouty SM, Abraham WM, de Garavilla L, Andrade-Gordon P, Hlasta DJ, He W, Hornby PJ, Damiano BP, Maryanoff BE.

Bioorg Med Chem Lett. 2004 Feb 9;14(3):591-6. Erratum in: Bioorg Med Chem Lett. 2004 May 3;14(9):2371. PMID: 14741249 [PubMed - indexed for MEDLINE]Related articles

Cannabinoid1 receptor in the dorsal vagal complex modulates lower oesophageal sphincter relaxation in ferrets.

Partosoedarso ER, Abrahams TP, Scullion RT, Moerschbaecher JM, Hornby PJ.

J Physiol. 2003 Jul 1;550(Pt 1):149-58.PMID: 12879865 [PubMed - indexed for MEDLINE]Related articlesFree article

Central mechanisms of lower esophageal sphincter control.

Hornby PJ, Abrahams TP, Partosoedarso ER.

Gastroenterol Clin North Am. 2002 Dec;31(4 Suppl):S11-20, v-vi. Review.PMID: 12489467 [PubMed - indexed for MEDLINE]Related articles

Orexins in rat dorsal motor nucleus of the vagus potently stimulate gastric motor function.

Krowicki ZK, Burmeister MA, Berthoud HR, Scullion RT, Fuchs K, Hornby PJ.

Am J Physiol Gastrointest Liver Physiol. 2002 Aug;283(2):G465-72.PMID: 12121895 [PubMed - indexed for MEDLINE]Related articlesFree article