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    Results: 1 to 20 of 56

    1.

    Positive selection of gene-modified cells increases the efficacy of pancreatic cancer suicide gene therapy.

    Martinez-Quintanilla J, Cascallo M, Gros A, Fillat C, Alemany R.

    Mol Cancer Ther. 2009 Nov;8(11):3098-107. Epub 2009 Nov 3.PMID: 19887556 [PubMed - in process]Related articles

    2.

    Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2.

    Azkona G, Amador-Arjona A, Obradors-Tarragó C, Varea E, Arqué G, Pinacho R, Fillat C, de la Luna S, Estivill X, Dierssen M.

    Genes Brain Behav. 2009 Sep 22. [Epub ahead of print]PMID: 19840121 [PubMed - as supplied by publisher]Related articles

    3.

    Urokinase-type plasminogen activator receptor transcriptionally controlled adenoviruses eradicate pancreatic tumors and liver metastasis in mouse models.

    Huch M, Gros A, José A, González JR, Alemany R, Fillat C.

    Neoplasia. 2009 Jun;11(6):518-28, 4 p following 528.PMID: 19484141 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Antitumor therapy based on cellular competition.

    Martinez-Quintanilla J, Cascallo M, Fillat C, Alemany R.

    Hum Gene Ther. 2009 Jul;20(7):728-38.PMID: 19281300 [PubMed - in process]Related articles

    5.

    Keratin 7 promoter selectively targets transgene expression to normal and neoplastic pancreatic ductal cells in vitro and in vivo.

    Pujal J, Huch M, José A, Abasolo I, Rodolosse A, Duch A, Sánchez-Palazón L, Smith FJ, McLean WH, Fillat C, Real FX.

    FASEB J. 2009 May;23(5):1366-75. Epub 2009 Jan 5.PMID: 19124560 [PubMed - indexed for MEDLINE]Related articles

    6.

    Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

    Ortiz-Abalia J, Sahún I, Altafaj X, Andreu N, Estivill X, Dierssen M, Fillat C.

    Am J Hum Genet. 2008 Oct;83(4):479-88.PMID: 18940310 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.

    Altafaj X, Ortiz-Abalia J, Fernández M, Potier MC, Laffaire J, Andreu N, Dierssen M, González-García C, Ceña V, Martí E, Fillat C.

    Neurobiol Dis. 2008 Dec;32(3):377-84. Epub 2008 Aug 16.PMID: 18773961 [PubMed - indexed for MEDLINE]Related articles

    8.

    DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome.

    Canzonetta C, Mulligan C, Deutsch S, Ruf S, O'Doherty A, Lyle R, Borel C, Lin-Marq N, Delom F, Groet J, Schnappauf F, De Vita S, Averill S, Priestley JV, Martin JE, Shipley J, Denyer G, Epstein CJ, Fillat C, Estivill X, Tybulewicz VL, Fisher EM, Antonarakis SE, Nizetic D.

    Am J Hum Genet. 2008 Sep;83(3):388-400. Epub 2008 Sep 4.PMID: 18771760 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Monitoring gene therapy by external imaging of mRNA: pilot study on murine erythropoietin.

    Segura J, Fillat C, Andreu D, Llop J, Millan O, de la Torre BG, Nikolovski Z, Gomez V, Andreu N, Pinyot A, Castelo R, Gispert JD, Pascual JA.

    Ther Drug Monit. 2007 Oct;29(5):612-8.PMID: 17898652 [PubMed - indexed for MEDLINE]Related articles

    10.

    Novel membrane cell projection defects in Wiskott-Aldrich syndrome B cells.

    Andreu N, Aran JM, Fillat C.

    Int J Mol Med. 2007 Oct;20(4):445-50.PMID: 17786274 [PubMed - indexed for MEDLINE]Related articles

    11.

    GCV modulates the antitumoural efficacy of a replicative adenovirus expressing the Tat8-TK as a late gene in a pancreatic tumour model.

    Cascante A, Abate-Daga D, Garcia-Rodríguez L, González JR, Alemany R, Fillat C.

    Gene Ther. 2007 Oct;14(20):1471-80. Epub 2007 Aug 23.PMID: 17713568 [PubMed - indexed for MEDLINE]Related articles

    12.

    Two novel mutations identified in the Wiskott-Aldrich syndrome protein gene cause Wiskott-Aldrich syndrome and thrombocytopenia.

    Andreu N, Matamoros N, Escudero A, Fillat C.

    Int J Mol Med. 2007 May;19(5):777-82.PMID: 17390083 [PubMed - indexed for MEDLINE]Related articles

    13.

    Targeting the CYP2B 1/cyclophosphamide suicide system to fibroblast growth factor receptors results in a potent antitumoral response in pancreatic cancer models.

    Huch M, Abate-Daga D, Roig JM, González JR, Fabregat J, Sosnowski B, Mazo A, Fillat C.

    Hum Gene Ther. 2006 Dec;17(12):1187-200.PMID: 17069538 [PubMed - indexed for MEDLINE]Related articles

    14.

    Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction.

    Dierssen M, Gratacòs M, Sahún I, Martín M, Gallego X, Amador-Arjona A, Martínez de Lagrán M, Murtra P, Martí E, Pujana MA, Ferrer I, Dalfó E, Martínez-Cué C, Flórez J, Torres-Peraza JF, Alberch J, Maldonado R, Fillat C, Estivill X.

    Neurobiol Dis. 2006 Nov;24(2):403-18. Epub 2006 Sep 11.PMID: 16963267 [PubMed - indexed for MEDLINE]Related articles

    15.

    Role of the putative heparan sulfate glycosaminoglycan-binding site of the adenovirus type 5 fiber shaft on liver detargeting and knob-mediated retargeting.

    Bayo-Puxan N, Cascallo M, Gros A, Huch M, Fillat C, Alemany R.

    J Gen Virol. 2006 Sep;87(Pt 9):2487-95.PMID: 16894186 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    HGF gene therapy attenuates renal allograft scarring by preventing the profibrotic inflammatory-induced mechanisms.

    Herrero-Fresneda I, Torras J, Franquesa M, Vidal A, Cruzado JM, Lloberas N, Fillat C, Grinyó JM.

    Kidney Int. 2006 Jul;70(2):265-74. Epub 2006 May 17.PMID: 16710352 [PubMed - indexed for MEDLINE]Related articles

    17.

    Non-invasive bioluminescence imaging for monitoring herpes simplex virus type 1 hematogenous infection.

    Burgos JS, Guzman-Sanchez F, Sastre I, Fillat C, Valdivieso F.

    Microbes Infect. 2006 Apr;8(5):1330-8. Epub 2006 Mar 24.PMID: 16682243 [PubMed - indexed for MEDLINE]Related articles

    18.

    Pitfalls and hopes in Down syndrome therapeutic approaches: in the search for evidence-based treatments.

    Dierssen M, Ortiz-Abalia J, Arqué G, de Lagrán MM, Fillat C.

    Behav Genet. 2006 May;36(3):454-68. Epub 2006 Mar 7. Review.PMID: 16520905 [PubMed - indexed for MEDLINE]Related articles

    19.

    Tat8-TK/GCV suicide gene therapy induces pancreatic tumor regression in vivo.

    Cascante A, Huch M, Rodríguez LG, González JR, Costantini L, Fillat C.

    Hum Gene Ther. 2005 Dec;16(12):1377-88.PMID: 16390269 [PubMed - indexed for MEDLINE]Related articles

    20.

    A novel Wiskott-Aldrich syndrome protein (WASP) complex mutation identified in a WAS patient results in an aberrant product at the C-terminus from two transcripts with unusual polyA signals.

    Andreu N, García-Rodríguez M, Volpini V, Frecha C, Molina IJ, Fontan G, Fillat C.

    J Hum Genet. 2006;51(2):92-7. Epub 2005 Dec 22.PMID: 16372137 [PubMed - indexed for MEDLINE]Related articles

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