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    Results: 1 to 20 of 26

    1.

    Evidence that alpha-synuclein does not inhibit phospholipase D.

    Rappley I, Gitler AD, Selvy PE, LaVoie MJ, Levy BD, Brown HA, Lindquist S, Selkoe DJ.

    Biochemistry. 2009 Feb 10;48(5):1077-83.PMID: 19146388 [PubMed - indexed for MEDLINE]Related articles

    2.

    Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

    Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.

    Nat Med. 2008 Aug;14(8):837-42. Epub 2008 Jun 22.PMID: 18568035 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway.

    Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL.

    J Neurosci. 2007 Mar 14;27(11):2866-75.PMID: 17360908 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Depression is associated with low plasma Abeta42 independently of cardiovascular disease in the homebound elderly.

    Qiu WQ, Sun X, Selkoe DJ, Mwamburi DM, Huang T, Bhadela R, Bergethon P, Scott TM, Summergrad P, Wang L, Rosenberg I, Folstein M.

    Int J Geriatr Psychiatry. 2007 Jun;22(6):536-42.PMID: 17096467 [PubMed - indexed for MEDLINE]Related articles

    5.

    Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation.

    Ye C, Walsh DM, Selkoe DJ, Hartley DM.

    Neurosci Lett. 2004 Aug 19;366(3):320-5.PMID: 15288443 [PubMed - indexed for MEDLINE]Related articles

    6.

    Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex.

    Fraering PC, LaVoie MJ, Ye W, Ostaszewski BL, Kimberly WT, Selkoe DJ, Wolfe MS.

    Biochemistry. 2004 Jan 20;43(2):323-33.PMID: 14717586 [PubMed - indexed for MEDLINE]Related articles

    7.

    Protofibrils of amyloid beta-protein inhibit specific K+ currents in neocortical cultures.

    Ye CP, Selkoe DJ, Hartley DM.

    Neurobiol Dis. 2003 Aug;13(3):177-90.PMID: 12901832 [PubMed - indexed for MEDLINE]Related articles

    8.

    Naturally occurring free D-aspartate is a nuclear component of cells in the mammalian hypothalamo-neurohypophyseal system.

    Wang H, Wolosker H, Morris JF, Pevsner J, Snyder SH, Selkoe DJ.

    Neuroscience. 2002;109(1):1-4.PMID: 11784695 [PubMed - indexed for MEDLINE]Related articles

    9.

    alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins.

    Sharon R, Goldberg MS, Bar-Josef I, Betensky RA, Shen J, Selkoe DJ.

    Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9110-5.PMID: 11481478 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Regulation of rat magnocellular neurosecretory system by D-aspartate: evidence for biological role(s) of a naturally occurring free D-amino acid in mammals.

    Wang H, Wolosker H, Pevsner J, Snyder SH, Selkoe DJ.

    J Endocrinol. 2000 Nov;167(2):247-52.PMID: 11054638 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain.

    Walsh DM, Tseng BP, Rydel RE, Podlisny MB, Selkoe DJ.

    Biochemistry. 2000 Sep 5;39(35):10831-9.PMID: 10978169 [PubMed - indexed for MEDLINE]Related articles

    12.

    L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity.

    Shearman MS, Beher D, Clarke EE, Lewis HD, Harrison T, Hunt P, Nadin A, Smith AL, Stevenson G, Castro JL.

    Biochemistry. 2000 Aug 1;39(30):8698-704.PMID: 10913280 [PubMed - indexed for MEDLINE]Related articles

    13.

    Phosphorylation of the beta-amyloid precursor protein at the cell surface by ectocasein kinases 1 and 2.

    Walter J, Schindzielorz A, Hartung B, Haass C.

    J Biol Chem. 2000 Aug 4;275(31):23523-9.PMID: 10806211 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates.

    Walsh DM, Hartley DM, Kusumoto Y, Fezoui Y, Condron MM, Lomakin A, Benedek GB, Selkoe DJ, Teplow DB.

    J Biol Chem. 1999 Sep 3;274(36):25945-52.PMID: 10464339 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier.

    Poduslo JF, Curran GL, Sanyal B, Selkoe DJ.

    Neurobiol Dis. 1999 Jun;6(3):190-9.PMID: 10408808 [PubMed - indexed for MEDLINE]Related articles

    16.

    Effects of the amyloid precursor protein Glu693-->Gln 'Dutch' mutation on the production and stability of amyloid beta-protein.

    Watson DJ, Selkoe DJ, Teplow DB.

    Biochem J. 1999 Jun 15;340 ( Pt 3):703-9.PMID: 10359654 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease.

    Wolfe MS, Xia W, Moore CL, Leatherwood DD, Ostaszewski B, Rahmati T, Donkor IO, Selkoe DJ.

    Biochemistry. 1999 Apr 13;38(15):4720-7.PMID: 10200159 [PubMed - indexed for MEDLINE]Related articles

    18.

    Amyloid beta peptide is not a candidate for the neurotrophic activities released from chromaffin cells.

    Legutko B, Staufenbiel M, Krieglstein K.

    Int J Dev Neurosci. 1998 Aug;16(5):347-52.PMID: 9829171 [PubMed - indexed for MEDLINE]Related articles

    19.

    The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex.

    Capell A, Grünberg J, Pesold B, Diehlmann A, Citron M, Nixon R, Beyreuther K, Selkoe DJ, Haass C.

    J Biol Chem. 1998 Feb 6;273(6):3205-11.PMID: 9452432 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Ectodomain phosphorylation of beta-amyloid precursor protein at two distinct cellular locations.

    Walter J, Capell A, Hung AY, Langen H, Schnölzer M, Thinakaran G, Sisodia SS, Selkoe DJ, Haass C.

    J Biol Chem. 1997 Jan 17;272(3):1896-903.PMID: 8999878 [PubMed - indexed for MEDLINE]Related articlesFree article

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