PubMed

A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans.

Hammell CM, Karp X, Ambros V.

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18668-73. Epub 2009 Oct 14.PMID: 19828440 [PubMed - in process]Related articles

pRB/CKI pathways at the interface of cell cycle and development.

Ambros V.

Cell Cycle. 2009 Nov 1;8(21):3433-4. Epub 2009 Nov 16. No abstract available. PMID: 19823011 [PubMed - in process]Related articles

Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets.

Hong X, Hammell M, Ambros V, Cohen SM.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):15085-90. Epub 2009 Aug 18.PMID: 19706460 [PubMed - indexed for MEDLINE]Related articlesFree article

Systematic analysis of dynamic miRNA-target interactions during C. elegans development.

Zhang L, Hammell M, Kudlow BA, Ambros V, Han M.

Development. 2009 Sep;136(18):3043-55. Epub 2009 Aug 12.PMID: 19675127 [PubMed - indexed for MEDLINE]Related articles

nhl-2 Modulates microRNA activity in Caenorhabditis elegans.

Hammell CM, Lubin I, Boag PR, Blackwell TK, Ambros V.

Cell. 2009 Mar 6;136(5):926-38.PMID: 19269369 [PubMed - indexed for MEDLINE]Related articles

mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts.

Hammell M, Long D, Zhang L, Lee A, Carmack CS, Han M, Ding Y, Ambros V.

Nat Methods. 2008 Sep;5(9):813-9.PMID: 19160516 [PubMed - indexed for MEDLINE]Related articles

Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity.

Martinez NJ, Ow MC, Reece-Hoyes JS, Barrasa MI, Ambros VR, Walhout AJ.

Genome Res. 2008 Dec;18(12):2005-15. Epub 2008 Nov 3.PMID: 18981266 [PubMed - indexed for MEDLINE]Related articlesFree article

The evolution of our thinking about microRNAs.

Ambros V.

Nat Med. 2008 Oct;14(10):1036-40. No abstract available. PMID: 18841144 [PubMed - indexed for MEDLINE]Related articles

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity.

Martinez NJ, Ow MC, Barrasa MI, Hammell M, Sequerra R, Doucette-Stamm L, Roth FP, Ambros VR, Walhout AJ.

Genes Dev. 2008 Sep 15;22(18):2535-49.PMID: 18794350 [PubMed - indexed for MEDLINE]Related articlesFree article

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans.

Ow MC, Martinez NJ, Olsen PH, Silverman HS, Barrasa MI, Conradt B, Walhout AJ, Ambros V.

Genes Dev. 2008 Sep 15;22(18):2520-34.PMID: 18794349 [PubMed - indexed for MEDLINE]Related articlesFree article

Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis.

Sokol NS, Xu P, Jan YN, Ambros V.

Genes Dev. 2008 Jun 15;22(12):1591-6.PMID: 18559475 [PubMed - indexed for MEDLINE]Related articlesFree article

Most Caenorhabditis elegans microRNAs are individually not essential for development or viability.

Miska EA, Alvarez-Saavedra E, Abbott AL, Lau NC, Hellman AB, McGonagle SM, Bartel DP, Ambros VR, Horvitz HR.

PLoS Genet. 2007 Dec;3(12):e215.PMID: 18085825 [PubMed - indexed for MEDLINE]Related articlesFree article

The small RNA repertoire of Dictyostelium discoideum and its regulation by components of the RNAi pathway.

Hinas A, Reimegård J, Wagner EG, Nellen W, Ambros VR, Söderbom F.

Nucleic Acids Res. 2007;35(20):6714-26. Epub 2007 Oct 4.PMID: 17916577 [PubMed - indexed for MEDLINE]Related articlesFree article

The regulation of genes and genomes by small RNAs.

Ambros V, Chen X.

Development. 2007 May;134(9):1635-41. Epub 2007 Apr 4.PMID: 17409118 [PubMed - indexed for MEDLINE]Related articlesFree article

Potent effect of target structure on microRNA function.

Long D, Lee R, Williams P, Chan CY, Ambros V, Ding Y.

Nat Struct Mol Biol. 2007 Apr;14(4):287-94. Epub 2007 Apr 1.PMID: 17401373 [PubMed - indexed for MEDLINE]Related articles

Characterization of microRNA expression levels and their biological correlates in human cancer cell lines.

Gaur A, Jewell DA, Liang Y, Ridzon D, Moore JH, Chen C, Ambros VR, Israel MA.

Cancer Res. 2007 Mar 15;67(6):2456-68.PMID: 17363563 [PubMed - indexed for MEDLINE]Related articlesFree article

The 2007 George W. Beadle Medal. Robert K. Herman.

Ambros V.

Genetics. 2007 Feb;175(2):465-6. No abstract available. PMID: 17322351 [PubMed - indexed for MEDLINE]Related articlesFree article

Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans.

Lee RC, Hammell CM, Ambros V.

RNA. 2006 Apr;12(4):589-97. Epub 2006 Feb 17.PMID: 16489184 [PubMed - indexed for MEDLINE]Related articlesFree article

The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding.

Hristova M, Birse D, Hong Y, Ambros V.

Mol Cell Biol. 2005 Dec;25(24):11059-72.PMID: 16314527 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental biology. Encountering microRNAs in cell fate signaling.

Karp X, Ambros V.

Science. 2005 Nov 25;310(5752):1288-9. No abstract available. PMID: 16311325 [PubMed - indexed for MEDLINE]Related articles