PubMed

Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in beta cells prevent autoimmune diabetes.

Horwitz MS, Efrat S, Christen U, von Herrath MG, Oldstone MB.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19450-4. Epub 2009 Nov 3.PMID: 19887639 [PubMed - in process]Related articles

Histopathology of type 1 diabetes: old paradigms and new insights.

Coppieters KT, von Herrath MG.

Rev Diabet Stud. 2009;6(2):85-96. Epub 2009 Aug 10.PMID: 19806238 [PubMed - in process]Related articles

Viral triggers for autoimmunity: Is the 'glass of molecular mimicry' half full or half empty?

Christen U, Hintermann E, Holdener M, von Herrath MG.

J Autoimmun. 2009 Aug 26. [Epub ahead of print]PMID: 19716269 [PubMed - as supplied by publisher]Related articles

Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice.

Filippi CM, Estes EA, Oldham JE, von Herrath MG.

J Clin Invest. 2009 Jun;119(6):1515-23. doi: 10.1172/JCI38503. Epub 2009 May 26.PMID: 19478458 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of the activating receptor NKG2D in autoimmunity.

Van Belle TL, von Herrath MG.

Mol Immunol. 2009 Nov;47(1):8-11. Epub 2009 Mar 14.PMID: 19286259 [PubMed - in process]Related articles

No significant CTL cross-priming by dendritic cell-derived exosomes during murine lymphocytic choriomeningitis virus infection.

Coppieters K, Barral AM, Juedes A, Wolfe T, Rodrigo E, Théry C, Amigorena S, von Herrath MG.

J Immunol. 2009 Feb 15;182(4):2213-20.PMID: 19201875 [PubMed - indexed for MEDLINE]Related articles

Viral trigger for type 1 diabetes: pros and cons.

Filippi CM, von Herrath MG.

Diabetes. 2008 Nov;57(11):2863-71. No abstract available. PMID: 18971433 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor-beta suppresses the activation of CD8+ T-cells when naive but promotes their survival and function once antigen experienced: a two-faced impact on autoimmunity.

Filippi CM, Juedes AE, Oldham JE, Ling E, Togher L, Peng Y, Flavell RA, von Herrath MG.

Diabetes. 2008 Oct;57(10):2684-92. Epub 2008 Aug 8.PMID: 18689691 [PubMed - indexed for MEDLINE]Related articlesFree article

Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.

Kotturi MF, Scott I, Wolfe T, Peters B, Sidney J, Cheroutre H, von Herrath MG, Buchmeier MJ, Grey H, Sette A.

J Immunol. 2008 Aug 1;181(3):2124-33.PMID: 18641351 [PubMed - indexed for MEDLINE]Related articlesFree article

Real-time imaging of the pancreas during development of diabetes.

Martinic MM, von Herrath MG.

Immunol Rev. 2008 Feb;221:200-13. Review.PMID: 18275484 [PubMed - indexed for MEDLINE]Related articles

Novel strategies to eliminate persistent viral infections.

Martinic MM, von Herrath MG.

Trends Immunol. 2008 Mar;29(3):116-24. Epub 2008 Feb 6. Review.PMID: 18258483 [PubMed - indexed for MEDLINE]Related articles

IL-10 and the resolution of infections.

Filippi CM, von Herrath MG.

J Pathol. 2008 Jan;214(2):224-30. Review.PMID: 18161757 [PubMed - indexed for MEDLINE]Related articles

Islet beta-cell death - fuel to sustain autoimmunity?

Filippi CM, von Herrath MG.

Immunity. 2007 Aug;27(2):183-5.PMID: 17723211 [PubMed - indexed for MEDLINE]Related articles

Cure of chronic viral infection by neutralizing antibody treatment.

Ejrnaes M, von Herrath MG.

Autoimmun Rev. 2007 Apr;6(5):267-71. Epub 2006 Oct 12. Review.PMID: 17412296 [PubMed - indexed for MEDLINE]Related articles

Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice.

Martinic MM, Juedes AE, Bresson D, Homann D, Skak K, Huber C, Ling E, Ejrnaes M, Wolfe T, Togher L, Christen U, von Herrath MG.

Diabetes. 2007 Apr;56(4):1059-68.PMID: 17395746 [PubMed - indexed for MEDLINE]Related articlesFree article

Exacerbated pathology of viral encephalitis in mice with central nervous system-specific autoantibodies.

Burrer R, Buchmeier MJ, Wolfe T, Ting JP, Feuer R, Iglesias A, von Herrath MG.

Am J Pathol. 2007 Feb;170(2):557-66.PMID: 17255324 [PubMed - indexed for MEDLINE]Related articlesFree article

Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies.

Ejrnaes M, von Herrath MG, Christen U.

Clin Dev Immunol. 2006 Jun-Dec;13(2-4):337-47. Review.PMID: 17162375 [PubMed - indexed for MEDLINE]Related articlesFree article

SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes.

Barral AM, Thomas HE, Ling EM, Darwiche R, Rodrigo E, Christen U, Ejrnaes M, Wolfe T, Kay TW, von Herrath MG.

J Autoimmun. 2006 Nov;27(3):166-73. Epub 2006 Oct 10.PMID: 17045460 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies exacerbate the severity of MHV-induced encephalitis.

Burrer R, von Herrath MG, Wolfe T, Rempel JD, Iglesias A, Buchmeier MJ.

Adv Exp Med Biol. 2006;581:399-402. Review. No abstract available. PMID: 17037567 [PubMed - indexed for MEDLINE]Related articles

Resolution of a chronic viral infection after interleukin-10 receptor blockade.

Ejrnaes M, Filippi CM, Martinic MM, Ling EM, Togher LM, Crotty S, von Herrath MG.

J Exp Med. 2006 Oct 30;203(11):2461-72. Epub 2006 Oct 9.PMID: 17030951 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of graft-versus-host disease by regulatory T cells: which level of antigen specificity?

Martinic MM, von Herrath MG.

Eur J Immunol. 2006 Sep;36(9):2299-303. Review.PMID: 16952145 [PubMed - indexed for MEDLINE]Related articles

Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies.

Ejrnaes M, von Herrath MG, Christen U.

Clin Dev Immunol. 2006 Mar;13(1):67-77. Review.PMID: 16603445 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease.

Fujinami RS, von Herrath MG, Christen U, Whitton JL.

Clin Microbiol Rev. 2006 Jan;19(1):80-94. Review.PMID: 16418524 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of intrinsic CTLA-4 expression has minimal effect on regulation of antiviral T-cell immunity.

Homann D, Dummer W, Wolfe T, Rodrigo E, Theofilopoulos AN, Oldstone MB, von Herrath MG.

J Virol. 2006 Jan;80(1):270-80.PMID: 16352552 [PubMed - indexed for MEDLINE]Related articlesFree article

Lost in translation: barriers to implementing clinical immunotherapeutics for autoimmunity.

von Herrath MG, Nepom GT.

J Exp Med. 2005 Nov 7;202(9):1159-62.PMID: 16275758 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet-specific expression of CXCL10 causes spontaneous islet infiltration and accelerates diabetes development.

Rhode A, Pauza ME, Barral AM, Rodrigo E, Oldstone MB, von Herrath MG, Christen U.

J Immunol. 2005 Sep 15;175(6):3516-24.PMID: 16148094 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunomodulatory dendritic cells require autologous serum to circumvent nonspecific immunosuppressive activity in vivo.

Haase C, Ejrnaes M, Juedes AE, Wolfe T, Markholst H, von Herrath MG.

Blood. 2005 Dec 15;106(13):4225-33. Epub 2005 Aug 23.PMID: 16118326 [PubMed - indexed for MEDLINE]Related articlesFree article

Infections and autoimmunity--good or bad?

Christen U, von Herrath MG.

J Immunol. 2005 Jun 15;174(12):7481-6. Review.PMID: 15944245 [PubMed - indexed for MEDLINE]Related articlesFree article

IP-10 and type 1 diabetes: a question of time and location.

Christen U, Von Herrath MG.

Autoimmunity. 2004 Aug;37(5):273-82. Review.PMID: 15672495 [PubMed - indexed for MEDLINE]Related articles

Pathogenesis of type 1 diabetes: a viewpoint.

von Herrath MG.

Adv Exp Med Biol. 2004;552:317-21. Review. No abstract available. PMID: 15622972 [PubMed - indexed for MEDLINE]Related articles

The role of innate immunity in autoimmunity.

Bach JF, Bendelac A, Brenner MB, Cantor H, De Libero G, Kronenberg M, Lanier LL, Raulet DH, Shlomchik MJ, von Herrath MG.

J Exp Med. 2004 Dec 20;200(12):1527-31.PMID: 15611284 [PubMed - indexed for MEDLINE]Related articlesFree article

Manipulating the type 1 vs type 2 balance in type 1 diabetes.

Christen U, von Herrath MG.

Immunol Res. 2004;30(3):309-25. Review.PMID: 15531772 [PubMed - indexed for MEDLINE]Related articles

A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes.

Christen U, Edelmann KH, McGavern DB, Wolfe T, Coon B, Teague MK, Miller SD, Oldstone MB, von Herrath MG.

J Clin Invest. 2004 Nov;114(9):1290-8.PMID: 15520861 [PubMed - indexed for MEDLINE]Related articlesFree article

IP-10 and type 1 diabetes: a question of time and location.

Christen U, von Herrath MG.

Autoimmunity. 2004 Jun;37(4):273-82. Review. Corrected and republished in: Autoimmunity. 2004 Aug;37(5):273-82. PMID: 15518041 [PubMed - indexed for MEDLINE]Related articles

Initiation of autoimmunity.

Christen U, von Herrath MG.

Curr Opin Immunol. 2004 Dec;16(6):759-67. Review.PMID: 15511670 [PubMed - indexed for MEDLINE]Related articles

Regulatory T-cells in type 1 diabetes.

Juedes AE, von Herrath MG.

Diabetes Metab Res Rev. 2004 Nov-Dec;20(6):446-51. Review.PMID: 15386802 [PubMed - indexed for MEDLINE]Related articles

Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions.

Renard CB, Kramer F, Johansson F, Lamharzi N, Tannock LR, von Herrath MG, Chait A, Bornfeldt KE.

J Clin Invest. 2004 Sep;114(5):659-68.PMID: 15343384 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors.

Madakamutil LT, Christen U, Lena CJ, Wang-Zhu Y, Attinger A, Sundarrajan M, Ellmeier W, von Herrath MG, Jensen P, Littman DR, Cheroutre H.

Science. 2004 Apr 23;304(5670):590-3.PMID: 15105501 [PubMed - indexed for MEDLINE]Related articlesFree article

T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.

Juedes AE, Rodrigo E, Togher L, Glimcher LH, von Herrath MG.

J Exp Med. 2004 Apr 19;199(8):1153-62.PMID: 15096540 [PubMed - indexed for MEDLINE]Related articlesFree article

Virally induced inflammation and therapeutic avenues in type 1 diabetes.

Christen U, Juedes A, Homann D, von Herrath MG.

Endocrinol Metab Clin North Am. 2004 Mar;33(1):45-58, viii. Review. No abstract available. PMID: 15053894 [PubMed - indexed for MEDLINE]Related articles

Induction, acceleration or prevention of autoimmunity by molecular mimicry.

Christen U, von Herrath MG.

Mol Immunol. 2004 Feb;40(14-15):1113-20. Review.PMID: 15036917 [PubMed - indexed for MEDLINE]Related articles

Microorganisms and autoimmunity: making the barren field fertile?

von Herrath MG, Fujinami RS, Whitton JL.

Nat Rev Microbiol. 2003 Nov;1(2):151-7. Review.PMID: 15035044 [PubMed - indexed for MEDLINE]Related articles

Virally induced inflammation triggers fratricide of Fas-ligand-expressing beta-cells.

Christen U, Darwiche R, Thomas HE, Wolfe T, Rodrigo E, Chervonsky A, Flavell RA, von Herrath MG.

Diabetes. 2004 Mar;53(3):591-6.PMID: 14988242 [PubMed - indexed for MEDLINE]Related articlesFree article

Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient.

Christen U, Benke D, Wolfe T, Rodrigo E, Rhode A, Hughes AC, Oldstone MB, von Herrath MG.

J Clin Invest. 2004 Jan;113(1):74-84.PMID: 14702111 [PubMed - indexed for MEDLINE]Related articlesFree article

Interfacing dendritic and natural killer cells: a tool for targeted tolerance induction?

Homann D, von Herrath MG.

Transplantation. 2003 Dec 27;76(12):1657-61. Review. No abstract available. PMID: 14688511 [PubMed - indexed for MEDLINE]Related articles

Using regulatory APCs to induce/maintain tolerance.

Juedes AE, Von Herrath MG.

Ann N Y Acad Sci. 2003 Nov;1005:128-37.PMID: 14679047 [PubMed - indexed for MEDLINE]Related articles

Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease.

Christen U, McGavern DB, Luster AD, von Herrath MG, Oldstone MB.

J Immunol. 2003 Dec 15;171(12):6838-45.PMID: 14662890 [PubMed - indexed for MEDLINE]Related articlesFree article

Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes.

Petersen JS, Bregenholt S, Apostolopolous V, Homann D, Wolfe T, Hughes A, De Jongh K, Wang M, Dyrberg T, Von Herrath MG.

Clin Exp Immunol. 2003 Oct;134(1):38-45.PMID: 12974752 [PubMed - indexed for MEDLINE]Related articlesFree article

Vaccination to prevent type 1 diabetes.

von Herrath MG.

Expert Rev Vaccines. 2002 Jun;1(1):25-8. Review.PMID: 12908509 [PubMed - indexed for MEDLINE]Related articles

Immune responsiveness, tolerance and dsRNA: implications for traditional paradigms.

von Herrath MG, Bot A.

Trends Immunol. 2003 Jun;24(6):289-93. Review.PMID: 12810099 [PubMed - indexed for MEDLINE]Related articles