PubMed

Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in {beta} cells prevent autoimmune diabetes.

Horwitz MS, Efrat S, Christen U, von Herrath MG, Oldstone MB.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19450-19454. Epub 2009 Nov 3.PMID: 19887639 [PubMed - as supplied by publisher]Related articles

Histopathology of type 1 diabetes: old paradigms and new insights.

Coppieters KT, von Herrath MG.

Rev Diabet Stud. 2009 Summer;6(2):85-96. Epub 2009 Aug 10.PMID: 19806238 [PubMed - in process]Related articles

Immunotherapy for the prevention and treatment of type 1 diabetes: optimizing the path from bench to bedside.

Bresson D, von Herrath M.

Diabetes Care. 2009 Oct;32(10):1753-68. No abstract available. PMID: 19794001 [PubMed - in process]Related articles

Viral triggers for autoimmunity: Is the 'glass of molecular mimicry' half full or half empty?

Christen U, Hintermann E, Holdener M, von Herrath MG.

J Autoimmun. 2009 Aug 26. [Epub ahead of print]PMID: 19716269 [PubMed - as supplied by publisher]Related articles

Genetic-induced Variations in the GAD65 T-cell Repertoire Governs Efficacy of Anti-CD3/GAD65 Combination Therapy in New-onset Type 1 Diabetes.

Bresson D, Fradkin M, Manenkova Y, Rottembourg D, von Herrath M.

Mol Ther. 2009 Aug 18. [Epub ahead of print]PMID: 19690518 [PubMed - as supplied by publisher]Related articles

Remodeling rodent models to mimic human type 1 diabetes.

von Herrath M, Nepom GT.

Eur J Immunol. 2009 Aug;39(8):2049-54.PMID: 19672901 [PubMed - indexed for MEDLINE]Related articles

Diabetes: A virus-gene collaboration.

von Herrath M.

Nature. 2009 May 28;459(7246):518-9. No abstract available. PMID: 19478773 [PubMed - indexed for MEDLINE]Related articles

Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice.

Filippi CM, Estes EA, Oldham JE, von Herrath MG.

J Clin Invest. 2009 Jun;119(6):1515-23. doi: 10.1172/JCI38503. Epub 2009 May 26.PMID: 19478458 [PubMed - indexed for MEDLINE]Related articlesFree article

How can we improve the translational landscape for a faster cure of type 1 diabetes?

von Herrath M, Chan A.

J Clin Invest. 2009 May;119(5):1061-5.PMID: 19422092 [PubMed - indexed for MEDLINE]Related articles

The role of the activating receptor NKG2D in autoimmunity.

Van Belle TL, von Herrath MG.

Mol Immunol. 2009 Nov;47(1):8-11. Epub 2009 Mar 14.PMID: 19286259 [PubMed - in process]Related articles

NKT cell-plasmacytoid dendritic cell cooperation via OX40 controls viral infection in a tissue-specific manner.

Diana J, Griseri T, Lagaye S, Beaudoin L, Autrusseau E, Gautron AS, Tomkiewicz C, Herbelin A, Barouki R, von Herrath M, Dalod M, Lehuen A.

Immunity. 2009 Feb 20;30(2):289-99. Epub 2009 Feb 12.PMID: 19217323 [PubMed - indexed for MEDLINE]Related articles

Interleukin-21 is required for the development of type 1 diabetes in NOD mice.

Sutherland AP, Van Belle T, Wurster AL, Suto A, Michaud M, Zhang D, Grusby MJ, von Herrath M.

Diabetes. 2009 May;58(5):1144-55. Epub 2009 Feb 10.PMID: 19208913 [PubMed - indexed for MEDLINE]Related articlesFree article

Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of beta cell mass.

Waldron-Lynch F, von Herrath M, Herold KC.

Novartis Found Symp. 2008;292:146-55; discussion 155-8, 202-3.PMID: 19203097 [PubMed - indexed for MEDLINE]Related articles

Resuscitating adaptive Tregs with combination therapies?

Bresson D, von Herrath M.

Novartis Found Symp. 2008;292:50-60; discussion 60-7, 122-9, 202-3.PMID: 19203092 [PubMed - indexed for MEDLINE]Related articles

Defining optimal immunotherapies for type 1 diabetes. Introduction.

von Herrath M.

Novartis Found Symp. 2008;292:1. No abstract available. PMID: 19203088 [PubMed - indexed for MEDLINE]Related articles

No significant CTL cross-priming by dendritic cell-derived exosomes during murine lymphocytic choriomeningitis virus infection.

Coppieters K, Barral AM, Juedes A, Wolfe T, Rodrigo E, Théry C, Amigorena S, von Herrath MG.

J Immunol. 2009 Feb 15;182(4):2213-20.PMID: 19201875 [PubMed - indexed for MEDLINE]Related articles

CD103 is dispensable for anti-viral immunity and autoimmunity in a mouse model of virally-induced autoimmune diabetes.

Fousteri G, Dave A, Juntti T, von Herrath M.

J Autoimmun. 2009 Feb;32(1):70-7. Epub 2009 Jan 21.PMID: 19162441 [PubMed - indexed for MEDLINE]Related articles

Animal models of human type 1 diabetes.

von Herrath M, Nepom GT.

Nat Immunol. 2009 Feb;10(2):129-32. Review.PMID: 19148193 [PubMed - indexed for MEDLINE]Related articles

Can we learn from viruses how to prevent type 1 diabetes?: the role of viral infections in the pathogenesis of type 1 diabetes and the development of novel combination therapies.

von Herrath M.

Diabetes. 2009 Jan;58(1):2-11. Review.PMID: 19114721 [PubMed - indexed for MEDLINE]Related articlesFree article

Viral trigger for type 1 diabetes: pros and cons.

Filippi CM, von Herrath MG.

Diabetes. 2008 Nov;57(11):2863-71. No abstract available. PMID: 18971433 [PubMed - indexed for MEDLINE]Related articlesFree article

Taking a closer look at the pancreas.

Coppieters K, von Herrath M.

Diabetologia. 2008 Dec;51(12):2145-7. No abstract available. PMID: 18949452 [PubMed - indexed for MEDLINE]Related articles

Transforming growth factor-beta suppresses the activation of CD8+ T-cells when naive but promotes their survival and function once antigen experienced: a two-faced impact on autoimmunity.

Filippi CM, Juedes AE, Oldham JE, Ling E, Togher L, Peng Y, Flavell RA, von Herrath MG.

Diabetes. 2008 Oct;57(10):2684-92. Epub 2008 Aug 8.PMID: 18689691 [PubMed - indexed for MEDLINE]Related articlesFree article

Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.

Kotturi MF, Scott I, Wolfe T, Peters B, Sidney J, Cheroutre H, von Herrath MG, Buchmeier MJ, Grey H, Sette A.

J Immunol. 2008 Aug 1;181(3):2124-33.PMID: 18641351 [PubMed - indexed for MEDLINE]Related articlesFree article

Animal models using lymphocytic choriomeningitis virus.

von Herrath M, Whitton JL.

Curr Protoc Immunol. 2001 May;Chapter 19:Unit 19.10.PMID: 18432751 [PubMed - indexed for MEDLINE]Related articles

Immunosuppression in islet transplantation.

Van Belle T, von Herrath M.

J Clin Invest. 2008 May;118(5):1625-8.PMID: 18431511 [PubMed - indexed for MEDLINE]Related articlesFree article

First-trimester human fetal pancreas transplantation for type 1 diabetes treatment: an alternative approach for achieving long-term graft survival?

Fousteri G, von Herrath M.

Diabetes. 2008 Mar;57(3):525-6. No abstract available. PMID: 18305145 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet antigen specific IL-10+ immune responses but not CD4+CD25+FoxP3+ cells at diagnosis predict glycemic control in type 1 diabetes.

Sanda S, Roep BO, von Herrath M.

Clin Immunol. 2008 May;127(2):138-43. Epub 2008 Mar 4.PMID: 18304876 [PubMed - indexed for MEDLINE]Related articles

Real-time imaging of the pancreas during development of diabetes.

Martinic MM, von Herrath MG.

Immunol Rev. 2008 Feb;221:200-13. Review.PMID: 18275484 [PubMed - indexed for MEDLINE]Related articles

Novel strategies to eliminate persistent viral infections.

Martinic MM, von Herrath MG.

Trends Immunol. 2008 Mar;29(3):116-24. Epub 2008 Feb 6. Review.PMID: 18258483 [PubMed - indexed for MEDLINE]Related articles

IL-10 and the resolution of infections.

Filippi CM, von Herrath MG.

J Pathol. 2008 Jan;214(2):224-30. Review.PMID: 18161757 [PubMed - indexed for MEDLINE]Related articles

Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation.

Simon G, Parker M, Ramiya V, Wasserfall C, Huang Y, Bresson D, Schwartz RF, Campbell-Thompson M, Tenace L, Brusko T, Xue S, Scaria A, Lukason M, Eisenbeis S, Williams J, Clare-Salzler M, Schatz D, Kaplan B, Von Herrath M, Womer K, Atkinson MA.

Diabetes. 2008 Feb;57(2):405-14. Epub 2007 Nov 26.PMID: 18039815 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes as a relapsing-remitting disease?

von Herrath M, Sanda S, Herold K.

Nat Rev Immunol. 2007 Dec;7(12):988-94. Review.PMID: 17982429 [PubMed - indexed for MEDLINE]Related articles

Stopping diabetes in its tracks: autologous non-myeloablative stem cell transplantation.

Fousteri G, Hayek A, von Herrath M.

Regen Med. 2007 Sep;2(5):845-51.PMID: 17907936 [PubMed - indexed for MEDLINE]Related articles

Islet beta-cell death - fuel to sustain autoimmunity?

Filippi CM, von Herrath MG.

Immunity. 2007 Aug;27(2):183-5.PMID: 17723211 [PubMed - indexed for MEDLINE]Related articles

Rational development of antigen-specific therapies for type 1 diabetes.

Fousteri G, Bresson D, von Herrath M.

Adv Exp Med Biol. 2007;601:313-9. Review.PMID: 17713020 [PubMed - indexed for MEDLINE]Related articles

Limitations in immunotherapy with CD3 antibodies: comment on the article by Drs. Chatenoud and Bach.

Bresson D, von Herrath M.

Rev Diabet Stud. 2005 Winter;2(4):187-9; discussion 190-1. Epub 2006 Feb 10. No abstract available. PMID: 17491693 [PubMed]Related articlesFree article

Immunotherapy after recent-onset type 1 diabetes: combinatorial treatment for achieving long-term remission in humans?

Bresson D, von Herrath M.

Rev Diabet Stud. 2004 Fall;1(3):108-12. Epub 2004 Nov 10. No abstract available. PMID: 17491672 [PubMed]Related articlesFree article

Mucosal exposure to antigen: cause or cure of type 1 diabetes?

Fousteri G, von Herrath M, Bresson D.

Curr Diab Rep. 2007 Apr;7(2):91-8. Review.PMID: 17425912 [PubMed - indexed for MEDLINE]Related articles

Moving towards efficient therapies in type 1 diabetes: to combine or not to combine?

Bresson D, von Herrath M.

Autoimmun Rev. 2007 Apr;6(5):315-22. Epub 2006 Oct 18. Review.PMID: 17412305 [PubMed - indexed for MEDLINE]Related articlesFree article

Cure of chronic viral infection by neutralizing antibody treatment.

Ejrnaes M, von Herrath MG.

Autoimmun Rev. 2007 Apr;6(5):267-71. Epub 2006 Oct 12. Review.PMID: 17412296 [PubMed - indexed for MEDLINE]Related articles

Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice.

Martinic MM, Juedes AE, Bresson D, Homann D, Skak K, Huber C, Ling E, Ejrnaes M, Wolfe T, Togher L, Christen U, von Herrath MG.

Diabetes. 2007 Apr;56(4):1059-68.PMID: 17395746 [PubMed - indexed for MEDLINE]Related articlesFree article

Translational mini-review series on type 1 diabetes: Immune-based therapeutic approaches for type 1 diabetes.

Staeva-Vieira T, Peakman M, von Herrath M.

Clin Exp Immunol. 2007 Apr;148(1):17-31. Review. Erratum in: Clin Exp Immunol. 2007 Jul;149(1):203. PMID: 17349010 [PubMed - indexed for MEDLINE]Related articlesFree article

Exacerbated pathology of viral encephalitis in mice with central nervous system-specific autoantibodies.

Burrer R, Buchmeier MJ, Wolfe T, Ting JP, Feuer R, Iglesias A, von Herrath MG.

Am J Pathol. 2007 Feb;170(2):557-66.PMID: 17255324 [PubMed - indexed for MEDLINE]Related articlesFree article

Progress in the development of immune-based therapies for type 1 diabetes mellitus.

von Herrath M, Rottembourg D, Bresson D.

BioDrugs. 2006;20(6):341-50. Review.PMID: 17176121 [PubMed - indexed for MEDLINE]Related articles

Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies.

Ejrnaes M, von Herrath MG, Christen U.

Clin Dev Immunol. 2006 Jun-Dec;13(2-4):337-47. Review.PMID: 17162375 [PubMed - indexed for MEDLINE]Related articlesFree article

SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes.

Barral AM, Thomas HE, Ling EM, Darwiche R, Rodrigo E, Christen U, Ejrnaes M, Wolfe T, Kay TW, von Herrath MG.

J Autoimmun. 2006 Nov;27(3):166-73. Epub 2006 Oct 10.PMID: 17045460 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies exacerbate the severity of MHV-induced encephalitis.

Burrer R, von Herrath MG, Wolfe T, Rempel JD, Iglesias A, Buchmeier MJ.

Adv Exp Med Biol. 2006;581:399-402. Review. No abstract available. PMID: 17037567 [PubMed - indexed for MEDLINE]Related articles

Resolution of a chronic viral infection after interleukin-10 receptor blockade.

Ejrnaes M, Filippi CM, Martinic MM, Ling EM, Togher LM, Crotty S, von Herrath MG.

J Exp Med. 2006 Oct 30;203(11):2461-72. Epub 2006 Oct 9.PMID: 17030951 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of graft-versus-host disease by regulatory T cells: which level of antigen specificity?

Martinic MM, von Herrath MG.

Eur J Immunol. 2006 Sep;36(9):2299-303. Review.PMID: 16952145 [PubMed - indexed for MEDLINE]Related articles

Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs.

Bresson D, Togher L, Rodrigo E, Chen Y, Bluestone JA, Herold KC, von Herrath M.

J Clin Invest. 2006 May;116(5):1371-81. Epub 2006 Apr 20.PMID: 16628253 [PubMed - indexed for MEDLINE]Related articlesFree article