PubMed

Overexpression of the wild-type SPT1 subunit lowers Desoxysphingolipid levels and rescues the phenotype of HSAN1.

Eichler FS, Hornemann T, McCampbell A, Kuljis D, Penno A, Vardeh D, Tamrazian E, Garofalo K, Lee HJ, Kini L, Selig M, Frosch M, Gable K, von Eckardstein A, Woolf CJ, Guan G, Harmon JM, Dunn TM, Brown RH Jr.

J Neurosci. 2009 Nov 18;29(46):14646-51.PMID: 19923297 [PubMed - in process]Related articles

The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases.

Hornemann T, Penno A, Rütti MF, Ernst D, Kivrak-Pfiffner F, Rohrer L, von Eckardstein A.

J Biol Chem. 2009 Sep 25;284(39):26322-30. Epub 2009 Aug 1.PMID: 19648650 [PubMed - indexed for MEDLINE]Related articles

Low- and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic beta-cells.

Rütti S, Ehses JA, Sibler RA, Prazak R, Rohrer L, Georgopoulos S, Meier DT, Niclauss N, Berney T, Donath MY, von Eckardstein A.

Endocrinology. 2009 Oct;150(10):4521-30. Epub 2009 Jul 23.PMID: 19628574 [PubMed - indexed for MEDLINE]Related articles

Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.

Tamehiro N, Mujawar Z, Zhou S, Zhuang DZ, Hornemann T, von Eckardstein A, Fitzgerald ML.

J Biol Chem. 2009 Sep 11;284(37):24881-90. Epub 2009 Jul 10.PMID: 19592499 [PubMed - indexed for MEDLINE]Related articles

Transendothelial lipoprotein transport and regulation of endothelial permeability and integrity by lipoproteins.

von Eckardstein A, Rohrer L.

Curr Opin Lipidol. 2009 Jun;20(3):197-205. Review.PMID: 19395962 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein transport through aortic endothelial cells involves scavenger receptor BI and ATP-binding cassette transporter G1.

Rohrer L, Ohnsorg PM, Lehner M, Landolt F, Rinninger F, von Eckardstein A.

Circ Res. 2009 May 22;104(10):1142-50. Epub 2009 Apr 16.PMID: 19372466 [PubMed - indexed for MEDLINE]Related articles

[Risk factors in atherosclerotic coronary heart disease]

Hof D, von Eckardstein A.

Ther Umsch. 2009 Apr;66(4):253-9. Review. German. PMID: 19358136 [PubMed - indexed for MEDLINE]Related articles

An improved method to determine serine palmitoyltransferase activity.

Rütti MF, Richard S, Penno A, von Eckardstein A, Hornemann T.

J Lipid Res. 2009 Jun;50(6):1237-44. Epub 2009 Jan 29.PMID: 19181628 [PubMed - indexed for MEDLINE]Related articles

European Lipoprotein Club: report of the 31st ELC Annual Conference, Tutzing, 8-11 September 2008.

Bernini F, Freeman D, Groen A, Heeren J, Kalopissis A, Kronenberg F, Lindstedt K, Parini P, Schuster G, Tybjaerg Hansen A, van Dij KW, von Eckardstein A.

Atherosclerosis. 2009 Jul;205(1):41-7. Epub 2008 Dec 7. No abstract available. PMID: 19150067 [PubMed - indexed for MEDLINE]Related articles

A systematic comparison of all mutations in hereditary sensory neuropathy type I (HSAN I) reveals that the G387A mutation is not disease associated.

Hornemann T, Penno A, Richard S, Nicholson G, van Dijk FS, Rotthier A, Timmerman V, von Eckardstein A.

Neurogenetics. 2009 Apr;10(2):135-43. Epub 2009 Jan 9.PMID: 19132419 [PubMed - indexed for MEDLINE]Related articles

Dopant assisted-atmospheric pressure photoionization (DA-APPI) liquid chromatography-mass spectrometry for the quantification of 27-hydroxycholesterol in plasma.

Karuna R, von Eckardstein A, Rentsch KM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 15;877(3):261-8. Epub 2008 Dec 24.PMID: 19121981 [PubMed - indexed for MEDLINE]Related articles

Pro-A-type natriuretic peptide and pro-adrenomedullin predict progression of chronic kidney disease: the MMKD Study.

Dieplinger B, Mueller T, Kollerits B, Struck J, Ritz E, von Eckardstein A, Haltmayer M, Kronenberg F; MMKD Study Group.

Kidney Int. 2009 Feb;75(4):408-14. Epub 2008 Dec 3.PMID: 19052536 [PubMed - indexed for MEDLINE]Related articles

[CME - Test 9]

von Eckardstein A.

Praxis (Bern 1994). 2008 Dec 3;97(24):1275-6. German. No abstract available. PMID: 19048504 [PubMed - indexed for MEDLINE]Related articles

Inhibition of protein kinase Cbeta prevents foam cell formation by reducing scavenger receptor A expression in human macrophages.

Osto E, Kouroedov A, Mocharla P, Akhmedov A, Besler C, Rohrer L, von Eckardstein A, Iliceto S, Volpe M, Lüscher TF, Cosentino F.

Circulation. 2008 Nov 18;118(21):2174-82. Epub 2008 Nov 3.PMID: 18981301 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: results from the SAPALDIA study.

Felber Dietrich D, Ackermann-Liebrich U, Schindler C, Barthélémy JC, Brändli O, Gold DR, Knöpfli B, Probst-Hensch NM, Roche F, Tschopp JM, von Eckardstein A, Gaspoz JM; Sapaldia team.

Eur J Appl Physiol. 2008 Oct;104(3):557-65. Epub 2008 Jul 3.PMID: 18597107 [PubMed - indexed for MEDLINE]Related articles

SERPINA1 gene variants in individuals from the general population with reduced alpha1-antitrypsin concentrations.

Zorzetto M, Russi E, Senn O, Imboden M, Ferrarotti I, Tinelli C, Campo I, Ottaviani S, Scabini R, von Eckardstein A, Berger W, Brändli O, Rochat T, Luisetti M, Probst-Hensch N; SAPALDIA Team.

Clin Chem. 2008 Aug;54(8):1331-8. Epub 2008 May 29.PMID: 18515255 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipidation of apolipoprotein A-I by ATP-binding cassette transporter (ABC) A1 generates an interaction partner for ABCG1 but not for scavenger receptor BI.

Lorenzi I, von Eckardstein A, Radosavljevic S, Rohrer L.

Biochim Biophys Acta. 2008 Jun-Jul;1781(6-7):306-13. Epub 2008 Apr 26.PMID: 18485926 [PubMed - indexed for MEDLINE]Related articles

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.

Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML.

Biochemistry. 2008 Jun 10;47(23):6138-47. Epub 2008 May 17.PMID: 18484747 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating alpha1-antitrypsin in the general population: determinants and association with lung function.

Senn O, Russi EW, Schindler C, Imboden M, von Eckardstein A, Brändli O, Zemp E, Ackermann-Liebrich U, Berger W, Rochat T, Luisetti M, Probst-Hensch NM; SAPALDIA Team.

Respir Res. 2008 Apr 25;9:35.PMID: 18439253 [PubMed - indexed for MEDLINE]Related articlesFree article

N-glycoprotein profiling of lung adenocarcinoma pleural effusions by shotgun proteomics.

Soltermann A, Ossola R, Kilgus-Hawelski S, von Eckardstein A, Suter T, Aebersold R, Moch H.

Cancer. 2008 Apr 25;114(2):124-33.PMID: 18327805 [PubMed - indexed for MEDLINE]Related articlesFree article

The neutral protease chymase degrades apolipoprotein E from high-density lipoproteins.

Lee-Rueckert M, von Eckardstein A, Kovanen PT.

Clin Chem Lab Med. 2008;46(3):421-3. No abstract available. PMID: 18254717 [PubMed - indexed for MEDLINE]Related articles

European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3-6 September 2007.

Hofker M, Bernini F, von Eckardstein A, Freeman D, Heeren J, Karpe F, Kalopissis A, Kronenberg F, Kuipers F, Lindstedt K, Parini P, Schuster G, van Dijk KW.

Atherosclerosis. 2008 Mar;197(1):471-9. No abstract available. PMID: 18243210 [PubMed - indexed for MEDLINE]Related articles

[CME--laboratory 4. "Tumor marker"]

von Eckardstein A.

Praxis (Bern 1994). 2007 Nov 7;96(45):1781-2. German. No abstract available. PMID: 18050604 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI.

Lorenzi I, von Eckardstein A, Cavelier C, Radosavljevic S, Rohrer L.

J Mol Med. 2008 Feb;86(2):171-83. Epub 2007 Oct 1.PMID: 17906976 [PubMed - indexed for MEDLINE]Related articles

European Lipoprotein Club: Report of the 29th ELC Annual Conference, Tutzing, 4-7 September 2006.

Hofker M, Calabresi L, von Eckardstein A, Heeren J, Karpe F, Kalopissis A, Kronenberg F, Kuipers F, Lindstedt K, Parini P, Schuster G, van Dijk KW.

Atherosclerosis. 2007 Aug;193(2):461-8. Epub 2007 Jan 3. No abstract available. PMID: 17640533 [PubMed - indexed for MEDLINE]Related articles

Automated urinalysis: first experiences and a comparison between the Iris iQ200 urine microscopy system, the Sysmex UF-100 flow cytometer and manual microscopic particle counting.

Shayanfar N, Tobler U, von Eckardstein A, Bestmann L.

Clin Chem Lab Med. 2007;45(9):1251-6. Erratum in: Clin Chem Lab Med. 2007;45(11):1570. PMID: 17635081 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein E interrupts interleukin-1beta signaling in vascular smooth muscle cells.

Kawamura A, Baitsch D, Telgmann R, Feuerborn R, Weissen-Plenz G, Hagedorn C, Saku K, Brand-Herrmann SM, von Eckardstein A, Assmann G, Nofer JR.

Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1610-7. Epub 2007 May 17.PMID: 17510469 [PubMed - indexed for MEDLINE]Related articlesFree article

[Hypercholesterolemia and control with therapy]

von Eckardstein A.

Praxis (Bern 1994). 2007 Apr 11;96(15):583. German. No abstract available. PMID: 17506387 [PubMed - indexed for MEDLINE]Related articles

[CME-Lab 2/Solution. Hypercholesteremia and therapy control]

von Eckardstein A.

Praxis (Bern 1994). 2007 Apr 25;96(17):701-2. German. No abstract available. PMID: 17491201 [PubMed - indexed for MEDLINE]Related articles

B-type natriuretic peptide concentrations predict the progression of nondiabetic chronic kidney disease: the Mild-to-Moderate Kidney Disease Study.

Spanaus KS, Kronenberg F, Ritz E, Schlapbach R, Fliser D, Hersberger M, Kollerits B, König P, von Eckardstein A; Mild-to-Moderate Kidney Disease Study Group.

Clin Chem. 2007 Jul;53(7):1264-72. Epub 2007 May 3.PMID: 17478561 [PubMed - indexed for MEDLINE]Related articlesFree article

In critically ill patients, B-type natriuretic peptide (BNP) and N-terminal pro-BNP levels correlate with C-reactive protein values and leukocyte counts.

Rudiger A, Fischler M, Harpes P, Gasser S, Hornemann T, von Eckardstein A, Maggiorini M.

Int J Cardiol. 2008 May 7;126(1):28-31. Epub 2007 May 2.PMID: 17477984 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes mellitus and risk of coronary heart disease: results of the 10-year follow-up of the PROCAM study.

Buyken AE, von Eckardstein A, Schulte H, Cullen P, Assmann G.

Eur J Cardiovasc Prev Rehabil. 2007 Apr;14(2):230-6.PMID: 17446801 [PubMed - indexed for MEDLINE]Related articles

Effects of passive smoking on heart rate variability, heart rate and blood pressure: an observational study.

Felber Dietrich D, Schwartz J, Schindler C, Gaspoz JM, Barthélémy JC, Tschopp JM, Roche F, von Eckardstein A, Brändli O, Leuenberger P, Gold DR, Ackermann-Liebrich U; SAPALDIA-team.

Int J Epidemiol. 2007 Aug;36(4):834-40. Epub 2007 Apr 17.PMID: 17440032 [PubMed - indexed for MEDLINE]Related articlesFree article

Myeloid-related protein 8/14 complex is released by monocytes and granulocytes at the site of coronary occlusion: a novel, early, and sensitive marker of acute coronary syndromes.

Altwegg LA, Neidhart M, Hersberger M, Müller S, Eberli FR, Corti R, Roffi M, Sütsch G, Gay S, von Eckardstein A, Wischnewsky MB, Lüscher TF, Maier W.

Eur Heart J. 2007 Apr;28(8):941-8. Epub 2007 Mar 26.PMID: 17387139 [PubMed - indexed for MEDLINE]Related articlesFree article

Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?

Hornemann T, Wei Y, von Eckardstein A.

Biochem J. 2007 Jul 1;405(1):157-64.PMID: 17331073 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for oxidative stress at elevated plasma thiol levels in chronic exposure to carbon disulfide (CS2) and coronary heart disease.

Wronska-Nofer T, Nofer JR, Stetkiewicz J, Wierzbicka M, Bolinska H, Fobker M, Schulte H, Assmann G, von Eckardstein A.

Nutr Metab Cardiovasc Dis. 2007 Sep;17(7):546-53. Epub 2006 Jul 7.PMID: 17134958 [PubMed - indexed for MEDLINE]Related articles

Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers.

Burkard I, von Eckardstein A, Waeber G, Vollenweider P, Rentsch KM.

Atherosclerosis. 2007 Sep;194(1):71-8. Epub 2006 Nov 14.PMID: 17107679 [PubMed - indexed for MEDLINE]Related articles

ATP-Binding cassette transporter A1 modulates apolipoprotein A-I transcytosis through aortic endothelial cells.

Cavelier C, Rohrer L, von Eckardstein A.

Circ Res. 2006 Nov 10;99(10):1060-6. Epub 2006 Oct 19.PMID: 17053191 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning and initial characterization of a new subunit for mammalian serine-palmitoyltransferase.

Hornemann T, Richard S, Rütti MF, Wei Y, von Eckardstein A.

J Biol Chem. 2006 Dec 8;281(49):37275-81. Epub 2006 Oct 4.PMID: 17023427 [PubMed - indexed for MEDLINE]Related articlesFree article

Relation of plasma thyroid-stimulating hormone levels to vascular lesions and atrophy of the brain in the elderly.

Reitz C, Kretzschmar K, Roesler A, von Eckardstein A, Berger K.

Neuroepidemiology. 2006;27(2):89-95. Epub 2006 Aug 22.PMID: 16926553 [PubMed - indexed for MEDLINE]Related articles

Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study.

Felber Dietrich D, Schindler C, Schwartz J, Barthélémy JC, Tschopp JM, Roche F, von Eckardstein A, Brändli O, Leuenberger P, Gold DR, Gaspoz JM, Ackermann-Liebrich U; SAPALDIA Team.

Europace. 2006 Jul;8(7):521-9.PMID: 16798766 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid efflux by the ATP-binding cassette transporters ABCA1 and ABCG1.

Cavelier C, Lorenzi I, Rohrer L, von Eckardstein A.

Biochim Biophys Acta. 2006 Jul;1761(7):655-66. Epub 2006 May 4. Review.PMID: 16798073 [PubMed - indexed for MEDLINE]Related articles

Role of the kidney in the metabolism of apolipoprotein A-IV: influence of the type of proteinuria.

Lingenhel A, Lhotta K, Neyer U, Heid IM, Rantner B, Kronenberg MF, König P, von Eckardstein A, Schober M, Dieplinger H, Kronenberg F.

J Lipid Res. 2006 Sep;47(9):2071-9. Epub 2006 Jun 20.PMID: 16788210 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparable increase of B-type natriuretic peptide and amino-terminal pro-B-type natriuretic peptide levels in patients with severe sepsis, septic shock, and acute heart failure.

Rudiger A, Gasser S, Fischler M, Hornemann T, von Eckardstein A, Maggiorini M.

Crit Care Med. 2006 Aug;34(8):2140-4.PMID: 16763507 [PubMed - indexed for MEDLINE]Related articles

Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimer's disease.

Wollmer MA, Kapaki E, Hersberger M, Muntwyler J, Brunner F, Tsolaki M, Akatsu H, Kosaka K, Michikawa M, Molyva D, Paraskevas GP, Lütjohann D, von Eckardstein A, Hock C, Nitsch RM, Papassotiropoulos A.

Am J Med Genet B Neuropsychiatr Genet. 2006 Jul 5;141B(5):534-6.PMID: 16752360 [PubMed - indexed for MEDLINE]Related articles

Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element.

Uehara Y, Miura S, von Eckardstein A, Abe S, Fujii A, Matsuo Y, Rust S, Lorkowski S, Assmann G, Yamada T, Saku K.

Atherosclerosis. 2007 Mar;191(1):11-21. Epub 2006 May 30.PMID: 16730733 [PubMed - indexed for MEDLINE]Related articles

Prognostic value of plasma N-terminal pro-brain natriuretic peptide in children with congenital heart defects and open-heart surgery.

Gessler P, Knirsch W, Schmitt B, Rousson V, von Eckardstein A.

J Pediatr. 2006 Mar;148(3):372-6.PMID: 16615970 [PubMed - indexed for MEDLINE]Related articles

Modulation of high-density lipoprotein cholesterol metabolism and reverse cholesterol transport.

Hersberger M, von Eckardstein A.

Handb Exp Pharmacol. 2005;(170):537-61. Review.PMID: 16596814 [PubMed - indexed for MEDLINE]Related articles

Risk factors for atherosclerotic vascular disease.

von Eckardstein A.

Handb Exp Pharmacol. 2005;(170):71-105. Review.PMID: 16596796 [PubMed - indexed for MEDLINE]Related articles

Binding, internalization and transport of apolipoprotein A-I by vascular endothelial cells.

Rohrer L, Cavelier C, Fuchs S, Schlüter MA, Völker W, von Eckardstein A.

Biochim Biophys Acta. 2006 Feb;1761(2):186-94. Epub 2006 Feb 20.PMID: 16546443 [PubMed - indexed for MEDLINE]Related articles