PubMed

Role of toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.

Dessing MC, Hirst RA, de Vos AF, van der Poll T.

PLoS One. 2009 Nov 24;4(11):e7993.PMID: 19956717 [PubMed - in process]Free article

Toll-like receptor 9 is not important for host defense against Haemophilus influenzae.

Wieland CW, Florquin S, van der Poll T.

Immunobiology. 2009 Nov 24. [Epub ahead of print]PMID: 19942314 [PubMed - as supplied by publisher]Related articles

CD44 DEFICIENCY IS ASSOCIATED WITH ENHANCED ESCHERICHIA COLI INDUCED PROINFLAMMATORY CYTOKINE AND CHEMOKINE RELEASE BY PERITONEAL MACROPHAGES.

van der Windt GJ, van 't Veer C, Florquin S, van der Poll T.

Infect Immun. 2009 Nov 9. [Epub ahead of print]PMID: 19901064 [PubMed - as supplied by publisher]Related articles

Pathogenesis, treatment, and prevention of pneumococcal pneumonia.

van der Poll T, Opal SM.

Lancet. 2009 Oct 31;374(9700):1543-56. Review.PMID: 19880020 [PubMed - indexed for MEDLINE]Related articles

Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis*

Stegenga ME, Vincent JL, Vail GM, Xie J, Haney DJ, Williams MD, Bernard GR, van der Poll T.

Crit Care Med. 2009 Oct 20. [Epub ahead of print]PMID: 19851093 [PubMed - as supplied by publisher]Related articles

Osteopontin is not crucial to protective immunity during murine tuberculosis.

van der Windt GJ, Wieland CW, Wiersinga WJ, Florquin S, van der Poll T.

Immunology. 2009 Sep;128(1 Suppl):e766-76. Epub 2009 Feb 17.PMID: 19740338 [PubMed - in process]Related articles

Expression and role of myeloid-related protein-14 in clinical and experimental sepsis.

van Zoelen MA, Vogl T, Foell D, Van Veen SQ, van Till JW, Florquin S, Tanck MW, Wittebole X, Laterre PF, Boermeester MA, Roth J, van der Poll T.

Am J Respir Crit Care Med. 2009 Dec 1;180(11):1098-106. Epub 2009 Sep 17.PMID: 19762566 [PubMed - in process]Related articles

Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats.

Hofstra JJ, Cornet AD, de Rooy BF, Vlaar AP, van der Poll T, Levi M, Zaat SA, Schultz MJ.

Crit Care. 2009;13(5):R145. Epub 2009 Sep 9.PMID: 19740417 [PubMed - in process]Related articlesFree article

Intestinal colonization with enterococcus faecium does not influence pulmonary defense against Pseudomonas aeruginosa in mice.

Leendertse M, Willems RJ, Giebelen IA, Roelofs JJ, Top J, Bonten MJ, van der Poll T.

PLoS One. 2009 Aug 27;4(8):e6775.PMID: 19710930 [PubMed - in process]Related articlesFree article

Enterococcal surface protein transiently aggravates Enterococcus faecium-induced urinary tract infection in mice.

Leendertse M, Heikens E, Wijnands LM, van Luit-Asbroek M, Teske GJ, Roelofs JJ, Bonten MJ, van der Poll T, Willems RJ.

J Infect Dis. 2009 Oct 1;200(7):1162-5.PMID: 19702507 [PubMed - indexed for MEDLINE]Related articles

Receptor for advanced glycation end products facilitates host defense during Escherichia coli-induced abdominal sepsis in mice.

van Zoelen MA, Schmidt AM, Florquin S, Meijers JC, de Beer R, de Vos AF, Nawroth PP, Bierhaus A, van der Poll T.

J Infect Dis. 2009 Sep 1;200(5):765-73. Erratum in: J Infect Dis. 2009 Nov 15;200(10):1629. PMID: 19627249 [PubMed - indexed for MEDLINE]Related articles

Intestinal Enterococcus faecium colonization improves host defense during polymicrobial peritonitis.

Leendertse M, Willems RJ, Oei GA, Florquin S, Bonten MJ, van der Poll T.

J Infect Dis. 2009 Sep 1;200(5):735-44.PMID: 19604046 [PubMed - indexed for MEDLINE]Related articles

Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia.

van Zoelen MA, van der Sluijs KF, Achouiti A, Florquin S, Braun-Pater JM, Yang H, Nawroth PP, Tracey KJ, Bierhaus A, van der Poll T.

Virology. 2009 Sep 1;391(2):265-73. Epub 2009 Jul 9.PMID: 19592063 [PubMed - indexed for MEDLINE]Related articles

Early activation of coagulation after allergen challenge in patients with allergic asthma.

Schouten M, VAN DE Pol MA, Levi M, VAN DER Poll T, VAN DER Zee JS.

J Thromb Haemost. 2009 Sep;7(9):1592-4. Epub 2009 Jun 22. No abstract available. PMID: 19552679 [PubMed - in process]Related articles

In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands.

de Vos AF, Pater JM, van den Pangaart PS, de Kruif MD, van 't Veer C, van der Poll T.

J Immunol. 2009 Jul 1;183(1):533-42.PMID: 19542464 [PubMed - indexed for MEDLINE]Related articles

Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis.

Wagenaar JF, Gasem MH, Goris MG, Leeflang M, Hartskeerl RA, van der Poll T, van 't Veer C, van Gorp EC.

PLoS Negl Trop Dis. 2009 Jun 2;3(6):e453.PMID: 19488407 [PubMed - in process]Related articlesFree article

The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury.

Leemans JC, Butter LM, Pulskens WP, Teske GJ, Claessen N, van der Poll T, Florquin S.

PLoS One. 2009 May 27;4(5):e5704.PMID: 19479087 [PubMed - indexed for MEDLINE]Related articlesFree article

The urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferi.

Hovius JW, Bijlsma MF, van der Windt GJ, Wiersinga WJ, Boukens BJ, Coumou J, Oei A, de Beer R, de Vos AF, van 't Veer C, van Dam AP, Wang P, Fikrig E, Levi MM, Roelofs JJ, van der Poll T.

PLoS Pathog. 2009 May;5(5):e1000447. Epub 2009 May 22.PMID: 19461880 [PubMed - indexed for MEDLINE]Related articlesFree article

Biologic effects of simvastatin in patients with aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled randomized trial.

Vergouwen MD, Meijers JC, Geskus RB, Coert BA, Horn J, Stroes ES, van der Poll T, Vermeulen M, Roos YB.

J Cereb Blood Flow Metab. 2009 Aug;29(8):1444-53. Epub 2009 May 20.PMID: 19458605 [PubMed - indexed for MEDLINE]Related articles

Burkholderia pseudomallei tropism and the melioidosis road map.

Wiersinga WJ, van der Poll T.

J Infect Dis. 2009 Jun 15;199(12):1720-2. No abstract available. PMID: 19456227 [PubMed - indexed for MEDLINE]Related articles

Priming of Alveolar Macrophages upon Instillation of Lipopolysaccharide in the Human Lung.

Hoogerwerf JJ, de Vos AF, Van't Veer C, Bresser P, de Boer A, Tanck MW, Draing C, van der Zee JS, van der Poll T.

Am J Respir Cell Mol Biol. 2009 May 15. [Epub ahead of print]PMID: 19448156 [PubMed - as supplied by publisher]Related articles

Procalcitonin kinetics in Legionella pneumophila pneumonia.

de Jager CP, de Wit NC, Weers-Pothoff G, van der Poll T, Wever PC.

Clin Microbiol Infect. 2009 Nov;15(11):1020-5. Epub 2009 Apr 24.PMID: 19438643 [PubMed - in process]Related articles

Urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury.

van Zoelen MA, Florquin S, de Beer R, Pater JM, Verstege MI, Meijers JC, van der Poll T.

Am J Pathol. 2009 Jun;174(6):2182-9. Epub 2009 May 12.PMID: 19435793 [PubMed - indexed for MEDLINE]Related articlesFree article

A new twist on the legend of granulocyte colony-stimulating factor in acute lung injury?

Schultz MJ, Juffermans NP, van der Poll T.

Crit Care Med. 2009 Apr;37(4):1506-7. No abstract available. PMID: 19318841 [PubMed - indexed for MEDLINE]Related articles

The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia.

van Zoelen MA, Schouten M, de Vos AF, Florquin S, Meijers JC, Nawroth PP, Bierhaus A, van der Poll T.

J Immunol. 2009 Apr 1;182(7):4349-56.PMID: 19299735 [PubMed - indexed for MEDLINE]Related articles

Diabetes and sepsis outcomes--it is not all bad news.

Yende S, van der Poll T.

Crit Care. 2009;13(1):117. Epub 2009 Feb 18.PMID: 19291261 [PubMed - in process]Related articles

ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.

Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T.

Microbes Infect. 2009 Apr;11(4):524-30. Epub 2009 Mar 13.PMID: 19286469 [PubMed - indexed for MEDLINE]Related articles

Immunity to Burkholderia pseudomallei.

Wiersinga WJ, van der Poll T.

Curr Opin Infect Dis. 2009 Apr;22(2):102-8. Review.PMID: 19276877 [PubMed - indexed for MEDLINE]Related articles

Cecal ligation and puncture induced sepsis impairs host defense against Enterococcus faecium peritonitis.

Leendertse M, Willems RJ, Giebelen IA, Florquin S, van den Pangaart PS, Bonten MJ, van der Poll T.

Intensive Care Med. 2009 May;35(5):924-32. Epub 2009 Feb 17.PMID: 19221713 [PubMed - indexed for MEDLINE]Related articles

Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo.

van Zoelen MA, Yang H, Florquin S, Meijers JC, Akira S, Arnold B, Nawroth PP, Bierhaus A, Tracey KJ, van der Poll T.

Shock. 2009 Mar;31(3):280-4.PMID: 19218854 [PubMed - indexed for MEDLINE]Related articles

Sepsis, coagulation, and antithrombin: old lessons and new insights.

Levi M, Schouten M, van der Poll T.

Semin Thromb Hemost. 2008 Nov;34(8):742-6. Epub 2009 Feb 12. Review.PMID: 19214912 [PubMed - indexed for MEDLINE]Related articles

Peritoneal macrophages are important for the early containment of Enterococcus faecium peritonitis in mice.

Leendertse M, Willems RJ, Giebelen IA, Roelofs JJ, van Rooijen N, Bonten MJ, van der Poll T.

Innate Immun. 2009 Feb;15(1):3-12.PMID: 19201820 [PubMed - indexed for MEDLINE]Related articles

Enterococcal surface protein Esp is not essential for cell adhesion and intestinal colonization of Enterococcus faecium in mice.

Heikens E, Leendertse M, Wijnands LM, van Luit-Asbroek M, Bonten MJ, van der Poll T, Willems RJ.

BMC Microbiol. 2009 Jan 29;9:19.PMID: 19178704 [PubMed - indexed for MEDLINE]Related articlesFree article

The acute-phase response impairs host defence against Enterococcus faecium peritonitis.

Leendertse M, Willems RJ, Giebelen IA, van den Pangaart PS, Bonten MJ, van der Poll T.

Immunology. 2009 Sep;128(1 Suppl):e335-42. Epub 2008 Oct 30.PMID: 19175794 [PubMed - in process]Related articles

Tissue factor as an initiator of coagulation and inflammation in the lung.

van der Poll T.

Crit Care. 2008;12 Suppl 6:S3. Epub 2008 Nov 26. Review.PMID: 19105796 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice.

van Maanen MA, Lebre MC, van der Poll T, LaRosa GJ, Elbaum D, Vervoordeldonk MJ, Tak PP.

Arthritis Rheum. 2009 Jan;60(1):114-22.PMID: 19116908 [PubMed - indexed for MEDLINE]Related articles

Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis).

Wiersinga WJ, van't Veer C, van den Pangaart PS, Dondorp AM, Day NP, Peacock SJ, van der Poll T.

Crit Care Med. 2009 Feb;37(2):569-76.PMID: 19114913 [PubMed - indexed for MEDLINE]Related articles

The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice.

Stegenga ME, Florquin S, de Vos AF, van der Poll T.

Crit Care Med. 2009 Feb;37(2):614-8.PMID: 19114898 [PubMed - indexed for MEDLINE]Related articles

Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide.

Hoogerwerf JJ, de Vos AF, Levi M, Bresser P, van der Zee JS, Draing C, von Aulock S, van der Poll T.

Crit Care Med. 2009 Feb;37(2):619-25.PMID: 19114879 [PubMed - indexed for MEDLINE]Related articles

Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and meta-analysis.

Brouwer MC, de Gans J, Heckenberg SG, Zwinderman AH, van der Poll T, van de Beek D.

Lancet Infect Dis. 2009 Jan;9(1):31-44. Epub 2008 Nov 25. Review.PMID: 19036641 [PubMed - indexed for MEDLINE]Related articles

Neutrophils are essential for rapid clearance of Enterococcus faecium in mice.

Leendertse M, Willems RJ, Giebelen IA, Roelofs JJ, Bonten MJ, van der Poll T.

Infect Immun. 2009 Jan;77(1):485-91. Epub 2008 Nov 10.PMID: 19001080 [PubMed - indexed for MEDLINE]Related articlesFree article

Early endotoxemia increases peripheral and hepatic insulin sensitivity in healthy humans.

van der Crabben SN, Blümer RM, Stegenga ME, Ackermans MT, Endert E, Tanck MW, Serlie MJ, van der Poll T, Sauerwein HP.

J Clin Endocrinol Metab. 2009 Feb;94(2):463-8. Epub 2008 Nov 4.PMID: 18984669 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury.

Pulskens WP, Teske GJ, Butter LM, Roelofs JJ, van der Poll T, Florquin S, Leemans JC.

PLoS One. 2008;3(10):e3596. Epub 2008 Oct 31.PMID: 18974879 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of natural anticoagulants in the pathogenesis and management of systemic activation of coagulation and inflammation in critically ill patients.

Levi M, van der Poll T.

Semin Thromb Hemost. 2008 Jul;34(5):459-68. Epub 2008 Oct 27. Review.PMID: 18956286 [PubMed - indexed for MEDLINE]Related articles

MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei.

Wiersinga WJ, Wieland CW, Roelofs JJ, van der Poll T.

PLoS One. 2008;3(10):e3494. Epub 2008 Oct 23.PMID: 18946505 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration.

Veninga H, Becker S, Hoek RM, Wobus M, Wandel E, van der Kaa J, van der Valk M, de Vos AF, Haase H, Owens B, van der Poll T, van Lier RA, Verbeek JS, Aust G, Hamann J.

J Immunol. 2008 Nov 1;181(9):6574-83.PMID: 18941248 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential dose-dependent effects of prednisolone on shedding of endothelial adhesion molecules during human endotoxemia.

Lemaire LC, de Kruif MD, Giebelen IA, van Zoelen MA, van't Veer C, van der Poll T.

Immunol Lett. 2008 Dec 22;121(2):93-6. Epub 2008 Oct 18.PMID: 18930765 [PubMed - indexed for MEDLINE]Related articles

CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice.

Wiersinga WJ, de Vos AF, Wieland CW, Leendertse M, Roelofs JJ, van der Poll T.

J Infect Dis. 2008 Nov 1;198(9):1388-97.PMID: 18855560 [PubMed - indexed for MEDLINE]Related articles

Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection.

Roelofs JJ, Rouschop KM, Teske GJ, Wagenaar GT, Claessen N, Weening JJ, van der Poll T, Florquin S.

Nephrol Dial Transplant. 2009 Mar;24(3):801-8. Epub 2008 Oct 8.PMID: 18842674 [PubMed - indexed for MEDLINE]Related articles

Stimulation of acetylcholine receptors impairs host defence during pneumococcal pneumonia.

Giebelen IA, Leendertse M, Florquin S, van der Poll T.

Eur Respir J. 2009 Feb;33(2):375-81. Epub 2008 Oct 1.PMID: 18829677 [PubMed - indexed for MEDLINE]Related articles